Finding genes that underlie complex traits.

Cited by (853)

Items 501–600 of 853

  1. From protein-disease associations to disease informatics
    Mehmet M Dalkilic · 2008 · Frontiers in bioscience
  2. A Systematic Strategy for the Discovery of Candidate Genes Responsible for Phenotypic Variation
    Paul Fisher, Harry A. Noyes, Stephen J. Kemp, Robert Stevens, Andy Brass · 2009 · Methods in molecular biology
  3. From Genetics to Mechanism of Disease Liability
    Andreas Rohrwasser, Paul C. Lott, Robert B. Weiss, Jean-Marc Lalouel · 2008 · Advances in genetics
  4. Fine mapping of the hyperglycemic and obesity QTL by congenic strains suggests multiple loci on rat chromosome 14
    Masuda Akhi, Hiroyuki Kose, Kozo Matsumoto · 2005 · The Journal of Medical Investigation
  5. Effects of Population Structure and Sex on Association Between Serotonin Receptors and Drosophila Heart Rate
    Naruo Nikoh, April Duty, Greg C. Gibson · 2004 · Genetics
  6. Approach to Infants and Children with Asthma
    Theresa W. Guilbert, Mark H. Mossand, Robert F. Lemanske · 2009 · Elsevier eBooks
  7. Whole-Genome Sequencing of 117 Chromosome Segment Substitution Lines for Genetic Analyses of Complex Traits in Rice
    Jiongjiong Fan, Hua Hua, Zhaowei Luo, Qi Zhang, Mengjiao Chen, Junyi Gong, Xin Wei, Zonghua Huang, Xuehui Huang, Qin Wang · 2022 · Rice
  8. Dopamine Receptor D1R and D3R and GRK4 Interaction in Hypertension
    Chunyu Zeng, Inés Armando, Jian Yang, Pedro A. José · 2023 · The Yale Journal of Biology and Medicine
  9. A MEMS-based approach to single nucleotide polymorphism genotyping
    Jing Zhu, Mirkó Palla, Stefano Ronca, Ronald J. Wapner, Jingyue Ju, Qiao Lin · 2012 · Sensors and Actuators A Physical
  10. Expression of Positional Candidates for Shell Thickness in the Chicken
    Alexei A. Sazanov, V A Stekol’nikova, Małgorzata Korczak−Abshire, Anna L. Sazanova, Kazimierz Jaszczak, G. Zięba, Tadeusz Malewski · 2007 · Poultry Science
  11. An efficient method for identifying statistical interactors in gene association networks
    Adin‐Cristian Andrei, Christina M. Kendziorski · 2009 · Biostatistics
  12. Use of Rat Genomics for Investigating the Metabolic Syndrome
    Michal Pravenec · 2009 · Methods in molecular biology
  13. The Mouse Atherosclerosis Locus at Chromosome 10 ( Ath11 ) Acts Early in Lesion Formation With Subcongenic Strains Delineating 2 Narrowed Regions
    Susanne Wolfrum, José M. Rodríguez, Marietta Tan, Kwan Y. Chen, Daniel Teupser, Jan L. Breslow · 2010 · Arteriosclerosis Thrombosis and Vascular Biology
  14. Research Actuality in the Genetics of Stroke
    Antonio Orlacchio, Giorgio Bernardi · 2006 · Clinical and Experimental Hypertension
  15. Prioritisation of associations between protein domains and complex diseases using domain–domain interaction networks
    Wenhui Wang, Wenyi Zhang, Rui Jiang, Yijun Luan · 2010 · IET Systems Biology
  16. Gene–environment studies: any advantage over environmental studies?
    Justo Lorenzo Bermejo, Kari Hemminki · 2007 · Carcinogenesis
  17. An optimal DNA pooling strategy for progressive fine mapping
    Xiao-Fei Chi, Xiang-Yang Lou, Mark C. K. Yang, Qingyao Shu · 2008 · Genetica
  18. Modifying the Message
    Joseph H. Nadeau · 2003 · Science
  19. Interdisciplinary sciences in the 21st century
    E.‐L. Winnacker · 2003 · Current Opinion in Biotechnology
  20. DRUGS AND THE FUTURE 1
    Luigi Rossini · 2005 · Università Politecnica delle Marche (Università Politecnica delle Marche)
  21. Jesting Pilate, genetic case–control association studies, and Heart
    DC Crossman, Hugh C Watkins · 2004 · Heart
  22. The Neurodevelopmental Model of Schizophrenia: Updated
    Carrie E. Bearden, STEPHANIE E. MEYER, Rachel L. Loewy, Tara A. Niendam, Tyrone D. Cannon · 2015 · Wiley eBooks
  23. Integrative genomics in cardiovascular medicine
    James S. Ware, Enrico G. Petretto, Stuart A. Cook · 2012 · Cardiovascular Research
  24. Mutations in the bovineABCG2 and the ovineMSTN gene added to the few quantitative trait nucleotides identified in farm animals: a mini-review
    M. H. Braunschweig · 2010 · Journal of Applied Genetics
  25. A Bacterial Artificial Chromosome Transgene with Polymorphic Cd72 Inhibits the Development of Glomerulonephritis and Vasculitis in MRL-Faslpr Lupus Mice
    Hisashi Oishi, Takahito Tsubaki, Tatsuhiko Miyazaki, Masao Ono, Masato Nose, Satoru Takahashi · 2013 · The Journal of Immunology
  26. Association mapping of cadmium, copper and hydrogen peroxide tolerance of roots and translocation capacities of cadmium and copper in Arabidopsis thaliana
    Tanveer Tazib, Yuriko Kobayashi, Takashi Ikka, Cheng‐Ri Zhao, Satoshi Iuchi, Masatomo Kobayashi, Kazuhiko Kimura, Hiroyuki Koyama · 2009 · Physiologia Plantarum
  27. Colorectal cancer as a complex disease: defining at-risk subjects in the general population – a preventive strategy
    Annika Lindblom, Xiaolei Zhou, Tao Liu, Annelie Liljegren, Johanna Skoglund, Tatjana Djureinovic · 2004 · Expert Review of Anticancer Therapy
  28. Genetic analysis of psychiatric disorders in humans
    Martine J. van Belzen, Peter Heutink · 2006 · Genes Brain & Behavior
  29. Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritis
    Xinhua Yu, Kristin Bauer, Dirk Koczan, Hans‐Jürgen Thiesen, Saleh Mohamed Ibrahim · 2007 · Arthritis Research & Therapy
  30. SNP Marker Discovery in Pima Cotton (Gossypium barbadense L.) Leaf Transcriptomes
    Pratibha Kottapalli, Mauricio Ulloa, Kameswara Rao Kottapalli, Paxton Payton, JOHN J. BURKE · 2016 · Genomics Insights
  31. Genetic testing for atherosclerosis risk: Inevitability or pipe dream?
    Matthew Bruce Lanktree, Jisun, Robert Alexander Hegele · 2008 · Canadian Journal of Cardiology
  32. Identifying Susceptibility Variants for Type 2 Diabetes
    Eleftheria Zeggini, Mark I. McCarthy · 2007 · Methods in molecular biology
  33. The Genetics of Common Diseases: 10 Million Times as Hard
    David B. Goldstein, Gianpiero L. Cavalleri, Kourosh R. Ahmadi · 2003 · Cold Spring Harbor Symposia on Quantitative Biology
  34. Predictive modeling of antibiotic eradication therapy success for new-onset Pseudomonas aeruginosa pulmonary infections in children with cystic fibrosis
    Lucía Graña-Miraglia, Nadia P. Morales-Lizcano, Pauline W. Wang, David M. Hwang, Yvonne C. W. Yau, Valerie J. Waters, David S. Guttman · 2023 · PLoS Computational Biology
  35. Yeast selection for wine flavor modulation
    Philippe Marullo, Denis Dubourdieu · 2021 · Elsevier eBooks
  36. Short communication: Variable number of tandem repeat polymorphisms in DGAT1 gene of buffaloes (Bubalus bubalis) is associated with milk constituents
    Diercles Francisco Cardoso, Gabriela Fernanda Peixoto de Souza, Rusbel Raúl Aspilcueta Borquis, Francisco Ribeiro de Araújo Neto, Gregório Miguel Ferreira de Camargo, Naudín Hurtado-Lugo, Daiane Cristina Becker Scalez, Ana Clara Lacerda Freitas, Lúcia Galvão de Albuquerque, Humberto Tonhati · 2015 · Journal of Dairy Science
  37. Genome-Wide Association Studies and Heritability Estimation in the Functional Genomics Era
    Dunia Pino Del Carpio, Roberto Daniel Lozano, Marnin D. Wolfe, Jean‐Luc Jannink · 2018 · Population genomics
  38. Transhumanist Genetic Enhancement: Creation of a ‘New Man’ Through Technological Innovation
    George Louis Mendz, Michael Cook · 2021 · The New Bioethics
  39. Morphometric and Genetic Description of Trophic Adaptations in Cichlid Fishes
    Leah DeLorenzo, Victoria DeBrock, Aldo Carmona Baez, Patrick J. Ciccotto, Erin N. Peterson, Clare Stull, Natalie B. Roberts, Reade B. Roberts, Kara E. Powder · 2022 · Biology
  40. Concordance of Aqueous Humor Flow in the Morning and at Night in Normal Humans
    Pauline A. Radenbaugh, Anju Goyal, Ning C. McLaren, David M. Reed, David C. Musch, Julia E. Richards, Sayoko Eileen Moroi · 2006 · Investigative Ophthalmology & Visual Science
  41. Ensuring the Safe Use of Genomic Medicine in Children
    Susanne B. Haga, Sharon F. Terry · 2009 · Clinical Pediatrics
  42. Semiparametric covariate-modulated local false discovery rate for genome-wide association studies
    Rong Zablocki, Richard A. Levine, Andrew Joseph Schork, Shujing Xu, Yunpeng Wang, Chun Chieh Fan, Wesley Kurt Thompson · 2017 · The Annals of Applied Statistics
  43. Intraspecific phenotypic variation in deer: the role of genetic and epigenetic processes
    Werner T. Flueck, Jo Anne M. Smith-Flueck · 2011 · Animal Production Science
  44. Bivariate genome-wide scan for metabolic phenotypes in non-diabetic Chinese individuals from the Stanford, Asia and Pacific Program of Hypertension and Insulin Resistance Family Study
    Y.-F. Chiu, Lee‐Ming Chuang, Hui‐Yi Kao, L.‐T. Ho, C.-T. Ting, Yi‐Jen Hung, Yii‐Der Ida Chen, Timothy A. Donlon, J. David Curb, Thomas Quertermous et al. · 2007 · Diabetologia
  45. Joint linkage and segregation analysis under multiallelic trait inheritance: simplifying interpretations for complex traits
    Elisabeth A. Rosenthal, Ellen M. Wijsman · 2010 · Genetic Epidemiology
  46. Genetic Mapping and Positional Cloning
    Timothy J. Aitman, Enrico G. Petretto, Jacques V. Behmoaras · 2009 · Methods in molecular biology
  47. Comparative Gene Map of Hypertriglyceridaemia
    O. äEDA · 2004
  48. IQ and the Wealth of Nations
    Ken Richardson · 2004 · Heredity
  49. Genome-wide association study of traits in sacred lotus uncovers MITE-associated variants underlying stamen petaloid and petal number variations
    Zhiyan Gao, Yuting Liang, Yuhan Wang, Yingjie Xiao, Jinming Chen, Xingyu Yang, Tao Shi · 2022 · Frontiers in Plant Science
  50. Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning
    Nancy B. Y. Tsui, Gregory Yin-Ming Cheng, Teresa Chung, Christopher Wai Kei Lam, Anita Yee, Peter K. C. Chung, Tsz-Ki Kwan, Elaine Yee-Ling Ko, Daihai He, Wing‐Tak Wong et al. · 2018 · Scientific Reports
  51. QTL in chicken: a look back and forward - a review.
    Alexei A. Sazanov, Anna L. Sazanova, O. Yu. Barkova, Kazimierz Jaszczak · 2010 · Animal Science Papers and Reports
  52. Number of Immunoreactive GnRH‐Containing Neurons Is Heritable in a Wild‐Derived Population of White‐Footed Mice (Peromyscus leucopus)
    Paul D. Heideman, David Broussard, Jessica A. Tate, Mauricio Avigdor · 2007 · Physiological and Biochemical Zoology
  53. Prediction of cis-QTLs in a pair of inbred mouse strains with the use of expression and haplotype data from public databases
    Richard A. Radcliffe, Michael J. Lee, Robert W. Williams · 2006 · Mammalian Genome
  54. Accelerating Genome-Wide Association Studies Using CUDA Compatible Graphics Processing Units
    Rui Jiang, Feng Zeng, Wangshu Zhang, Xuebing Wu, Zhihong Yu · 2009 · International Joint Conferences on Bioinformatics, Systems Biology and Intelligent Computing
  55. Genetics of Graves' disease: the lost concept.
    Roy Panusunan Sibarani · 2009 · PubMed
  56. Genetic Regulation of the Variation in Pubertal Timing
    Craig A. Hodges, Mark R. Palmert · 2007 · Humana Press eBooks
  57. Absence of an Interaction between the Rf-1 and Rf-5 QTLs Influencing Susceptibility to Renal Damage in Rats
    Sabine J. van Dijk, Patricia A. C. Specht, Jozef Lazar, Howard J. Jacob, Abraham P. Provoost · 2006 · Nephron Experimental Nephrology
  58. Formaldehyde–protein Conjugate-specific Antibodies in Rats Exposed to Formaldehyde
    Hui Li, Jianling Wang, Rolf König, G.A.S. Ansari, M. Firoze Khan · 2007 · Journal of Toxicology and Environmental Health
  59. Cross model validated feature selection based on gene clusters
    Lars Gidskehaug, Endre Anderssen, Bjørn Kåre Alsberg · 2006 · Chemometrics and Intelligent Laboratory Systems
  60. Genomics and Biology Come Together to Fight HIV
    D. Goldstein · 2008 · PLoS Biology
  61. Replication of Small Effect Quantitative Trait Loci for Behavioral Traits Facilitated by Estimation of Effect Size from Independent Cohorts
    B. Bennett, P. Carosone-Link · 2006 · Genes, Brain and Behavior
  62. Linkage of Graves’ disease to the human leucocyte antigen region in the Chinese‐Han population in Taiwan
    Pei‐Lung Chen, Cathy S.J. Fann, C.-S. Chang, I‐Lin Wu, Wei‐Yih Chiu, Chin‐Yu Lin, Wei‐Shiung Yang, Tien‐Chun Chang · 2007 · Clinical Endocrinology
  63. Comparative Gene Map of Hypertriglyceridaemia
    Ond⊘řej Šeda · 2004 · Folia Biologica
  64. Positional Identification of Structural and Regulatory Quantitative Trait Nucleotides in Domestic Animal Species
    Michel Georges, Leif Andersson · 2003 · Cold Spring Harbor Symposia on Quantitative Biology
  65. Human genetics of diabetic nephropathy
    Zihui Tang, Fengfang Zeng, Xiuzhen Zhang · 2015 · Renal Failure
  66. Jaw size variation is associated with a novel craniofacial function for galanin receptor 2 in an adaptive radiation of pupfishes
    M. Fernanda Palominos, Vanessa Muhl, Emilie J. Richards, Craig T. Miller, Christopher H. Martin · 2023 · Proceedings of the Royal Society B Biological Sciences
  67. Identifying and prioritizing disease-related genes based on the network topological features
    Zhanchao Li, Yan-Hua Lai, Li-Li Chen, Yun Xia Xie, Zong Dai, Xiaoyong Zou · 2014 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  68. Life or Death? A Physiogenomic Approach to Understand Individual Variation in Responses to Hemorrhagic Shock
    Harold G. Klemcke, Bina Joe, Rajiv Rose, Kathy L. Ryan · 2011 · Current Genomics
  69. Complex Quantitative Traits Cracked by the Mouse Inter-Subspecific Consomic Strains
    Toyoyuki Takada, Toshihiko Shiroishi · 2012 · EXPERIMENTAL ANIMALS
  70. Genetic Dissociation of Dacryoadenitis and Sialadenitis in a Sjogren’s Syndrome Mouse Model with Common and Different Susceptibility Gene Loci
    Tomoyuki Kamao, Tatsuhiko Miyazaki, Yoshiko Soga, Hiroaki Komori, Miho Terada, Yuichi Ohashi, Masato Nose · 2009 · Investigative Ophthalmology & Visual Science
  71. Prediction of cancer prognosis with the genetic basis of transcriptional variations
    Harikrishna Paik, Eunjung Lee, In Ho Park, Junho Kim, Doheon Lee · 2011 · Genomics
  72. Novel Strategy Using F1-Congenic Mice for Validation of QTLs
    Daniel Teupser, Susanne Wolfrum, Marietta Tan, Adam D. Persky, Hayes M. Dansky, Jan L. Breslow · 2009 · Arteriosclerosis Thrombosis and Vascular Biology
  73. Polimorfismos reguladores y su participación en la patogenia de enfermedades complejas en la era posgenómica
    Jesús Hernández‐Romano, Jesús Martínez-Barnetche, Verónica Valverde-Garduño · 2009 · Salud Pública de México
  74. Association of Amine-Receptor DNA Sequence Variants with Associative Learning in the Honeybee
    Malgorzata Lagisz, Alison R. Mercer, Charlotte de Mouzon, Luana L. S. Santos, Shinichi Nakagawa · 2015 · Behavior Genetics
  75. Shared genomic segments in high‐risk multigenerational pedigrees with gastroschisis
    Marcia L. Feldkamp, Sergey V. Krikov, John Gardner, Myke Madsen, Todd M. Darlington, Rob Sargent, Nicola J. Camp · 2019 · Birth Defects Research
  76. Genome-Wide Linkage Analysis of Hemodynamic Parameters Under Mental and Physical Stress in Extended Omani Arab Pedigrees: The Oman Family Study
    Mohammed O. Hassan, Deepali Jaju, Venkata Saroja Voruganti, Riad Bayoumi, Sulayma Albarwani, Saeed Al‐Yahyaee, Afshin Aslani, Harold Snieder, Juan Carlos López-Alvarenga, Zahir M. Al-Anqoudi et al. · 2011 · Twin Research and Human Genetics
  77. Population Genomics of Drug Response
    Eva Charlotte Halapi, Kāri Stefánsson, Hakon H. Hakonarson · 2004 · American Journal of PharmacoGenomics
  78. Curve-based multivariate distance matrix regression analysis: application to genetic association analyses involving repeated measures
    Rany M. Salem, Daniel T. O’Connor, Nicholas J. Schork · 2010 · Physiological Genomics
  79. Complex disorders reloaded: causality, action, reaction, cause and effect
    Kristopher J. L. Irizarry, Simon J. Galbraith · 2004 · Molecular Psychiatry
  80. Mapping genes and pathways in autoimmune disease
    Anne Spurkland, Ludvig Magne Sollid · 2006 · Trends in Immunology
  81. Type-2 diabetes related intermediate phenotypic traits in north Indian diabetics
    Sandeep Kumar Mathur, Piyush Chandra, Sandhya Mishra, Peeyush Ajmera, Praveen Sharma · 2007 · Indian Journal of Clinical Biochemistry
  82. TraitMap: an XML-based genetic-map database combining multigenic loci and biomolecular networks
    Naohiko Heida, Yoshikazu Hasegawa, Yoshiki Mochizuki, Katsura Hirosawa, Akihiko Konagaya, Tetsuro Toyoda · 2004 · Bioinformatics
  83. Human personality traits are associated with individual environmental traits in male adolescents—a pilot study
    Toshiaki Nakamura-Tani · 2004 · Comprehensive Psychiatry
  84. A forest-based feature screening approach for large-scale genome data with complex structures
    Gang Wang, Guifang Fu, Christopher D. Corcoran · 2015 · BMC Genetics
  85. Genetic determinants of swallowing impairment, recovery and responsiveness to treatment
    Alicja Raginis‐Zborowska, Neil Pendleton, Shaheen Hamdy · 2016 · Current Physical Medicine and Rehabilitation Reports
  86. Mixture cure model with an application to interval mapping of quantitative trait loci
    Mengling Liu, Wenbin Lu, Yongzhao Shao · 2006 · Lifetime Data Analysis
  87. Role of pharmacogenomics in drug development
    Hakon H. Hakonarson, Kāri Stefánsson · 2004 · Drug Development Research
  88. Genesis of phenotypic and genotypic diversity in land plants: The present as the key to the past
    Richard M. Bateman, William A. DiMichele · 2003 · Systematics and Biodiversity
  89. Tlr5 is not primarily associated with susceptibility to Salmonella Typhimurium infection in MOLF/Ei mice
    Isabelle Angers, Vanessa Sancho‐Shimizu, Albert Descoteaux, Andrew T. Gewirtz, Danielle Malo · 2006 · Mammalian Genome
  90. Nine steps to proteomic wisdom: A practical guide to using protein‐protein interaction networks and molecular pathways as a framework for interpreting disease proteomic profiles
    Ruth Isserlin, Andrew Emili · 2007 · PROTEOMICS - CLINICAL APPLICATIONS
  91. Bayesian semiparametric copula estimation with application to psychiatric genetics
    Ori Rosen, Wesley K. Thompson · 2015 · Biometrical Journal
  92. Reporting 678 putative cSNPs from full‐length enriched cDNA sequences of the Korean native pig
    K. Park, Vijaya ramu Dirisala, Y. Oh, Hojun Choi, K.T. Lee, Jin‐Hoi Kim, H.T. Lee, Kun‐Ho Seo, Chankyu Park · 2009 · Journal of Animal Breeding and Genetics
  93. Translating knowledge into practice in the "post-genome" era
    Charles R. Scriver · 2004 · Acta Paediatrica
  94. Chromosomal Substitution Strategies to Localize Genomic Regions Related to Complex Traits
    Allen W. Cowley, Melinda R. Dwinell · 2020 · Comprehensive physiology
  95. Function-Genes and Disease-Genes Prediction Based on Network Embedding and One-Class Classification
    Weiyu Shi, Yan Zhang, Yeqing Sun, Zhengkui Lin · 2024 · Interdisciplinary Sciences Computational Life Sciences
  96. Fine-Mapping and Genetic Analysis of the Loci Affecting Hepatic Iron Overload in Mice
    Xin Guo, Zhuzhen Zhang, Fan Zhang, Yunlong Tao, Peng An, Qian Wu, Chia-Yu Wang, Mitchell D. Knutson, Fudi Wang · 2013 · PLoS ONE
  97. Cancer core modules identification through genomic and transcriptomic changes correlation detection at network level
    Wenting Li, Rui Wang, Linfu Bai, Zhangming Yan, Zhirong Sun · 2012 · BMC Systems Biology
  98. Exploiting the potential of next-generation sequencing in genomic medicine
    Anna Maria Pinto, Francesca Ariani, Laura Bianciardi, Sergio Daga, Alessandra Renieri · 2016 · Expert Review of Molecular Diagnostics
  99. Genetic dissection of QTLs and differentiation analysis of alleles for heading date genes in rice
    Hua Zhang, Shuyi Liu, Chen Gao, Xu Liu, Xuan Ning, Yongyi Yang, Wei Liu, Hanfeng Ding, Fangyin Yao · 2018 · PLoS ONE
  100. Generative prediction of causal gene sets responsible for complex traits
    Benjamin Kuznets-Speck, Buduka K. Ogonor, Thomas P. Wytock, Adilson E. Motter · 2025 · Proceedings of the National Academy of Sciences