Chimeric Nucleases Stimulate Gene Targeting in Human Cells

Cited by (740)

Items 601–700 of 740

  1. Molecular Aspects of Zinc Finger Nucleases (ZFNs)-Mediated Gene Editing in Rat Embryos
    Xiaoxia Cui · 2018 · Methods in molecular biology
  2. Characterization and design of C2H2 zinc finger proteins as custom DNA binding domains
    Jeffry D. Sander · 2008 · Iowa State University Digital Repository (Iowa State University)
  3. Human Stem‐Cell‐Derived Cardiomyocytes in Drug Discovery and Toxicity Testing
    Kornélia Szebényi, Adrienn Péntek, Nóra Varga, Zsuzsa Erdei, Gergő Vőfély, Tamás István Orbán, Balázs Sarkadi, Ágota Apáti · 2014 · Wiley eBooks
  4. RNA-guided Transcriptional Regulation in Plants via dCas9 Chimeric Proteins
    Hatoon Baazim · 2014 · King Abdullah University of Science and Technology Repository (King Abdullah University of Science and Technology)
  5. Combining Crowdsourcing and Deep Learning to Assess Public Opinion on CRISPR-Cas9
    Martin Müller, Manuel Schneider, Marcel Salathé, Effy Vayena · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  6. TRACE-Seq Reveals Clonal Reconstitution Dynamics of Gene Targeted Human Hematopoietic Stem Cells
    Rajiv Sharma, Daniel P. Dever, Ciaran M. Lee, Armon Azizi, Yidan Pan, Joab Camarena, Thomas Köhnke, Gang Bao, Matthew Hebden Porteus, Ravindra Majeti · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  7. Efficient genome editing using CRISPR/Cas9 technology and its application for identifying Sesquiterpene synthases involved in the biosynthesis of Steperoxides in Steccherinum ochraceum
    Jia-Yu Shen, Fei-Hong Mao, Qiwen Wang, Pei-Pei Ou, Ji‐Kai Liu, Qunfei Zhao, Qingli He · 2024 · Fungal Genetics and Biology
  8. CRISPR-based genome editing in human embryos: a review of efficiency, safety, and ethical implications
    Jinwen Yin, Haiping Wen, Jiajun Zeng, Yan Sun, Xiao Chen, Long Guo Jin, Yali Song, Siyu Xia · 2026 · Biology of Reproduction
  9. Stem Cell Gene Therapy
    Brian R. Davis, Nicole L. Prokopishyn · 2004 · Elsevier eBooks
  10. Genome engineering: unconventional biochemistry and food security
    Vedpal Singh Malik · 2012 · Journal of Plant Biochemistry and Biotechnology
  11. Establishment of a cell line carrying single copy of an exogenous mutant reporter gene for assaying the biological activity of ZFNs
    Weifeng Zhang, Xiaojing Zheng, Yueying Wang, Qinwen Mao, Haibin Xia · 2012 · Journal of Biotechnology
  12. Nuclease Mediated Targeted Genome Modification in Mammalian Cells
    Jenny C. Barker, Richard A. Voit, Matthew Hebden Porteus · 2012 · Topics in current genetics
  13. Stimulation of AAV Gene Editing via DSB Repair
    Angela M. Mitchell, Rachel J. Moser, Richard Jude Samulski, Matthew Louis Hirsch · 2016 · Advances in experimental medicine and biology
  14. Cellular Therapies: Gene Editing and Next-Gen CAR T Cells
    Thomas James Cradick · 2016 · Springer eBooks
  15. Genome Editing in Human Pluripotent Stem Cells
    Liuhong Cai, Yoon-Young Jang, Zhaohui Ye · 2016 · Stem cell biology and regenerative medicine
  16. Genome Editing: A Review of the Challenges and Approaches
    Dimple Sharma, Harmanpreet Kaur, Harsimran Kaur Kapoor, Rajat Sharma, Harpreet Kaur, Mohd Kyum · 2022 · Springer eBooks
  17. Therapeutic targeting non-coding RNAs
    Roslyn Michelle Ray, Andreea Daniela Lazăr, Liliana-Roxana Balahura, Alexandra Dobranici, Marieta Costache, Sorina Dinescu · 2023 · Elsevier eBooks
  18. New tools for genome editing
    Kui Li, Yong Zhang, Bingyuan Wang, Yulian Mu, Rong Zhou, Yunping Dai, Liangxue Lai, Jinxue Ruan, Zhiguo Liu, Tianwen Wu et al. · 2024 · Elsevier eBooks
  19. Targeted Mutagenesis
    Kwang‐Wook Choi · 2024 · KAIST research series
  20. A Story of Perseverance: An Interview with Matthew Porteus
    Matthew Hebden Porteus, Kevin Davies · 2024 · The CRISPR Journal
  21. CRISPR-based genome editing of a diurnal rodent, Nile grass rat (Arvicanthis niloticus)
    Huirong Xie, Katrina Linning‐Duffy, Elena Y. Demireva, Huishi Toh, Bana Abolibdeh, Jiaming Shi, Bo Zhou, Shigeki Iwase, Lili Yan · 2024 · BMC Biology
  22. Human genomic repair at your fingertips
    Michael S. Eisenstein · 2005 · Nature Methods
  23. Gene Editing in Adult Hematopoietic Stem Cells
    Sergio López-Manzaneda, Sara Fañanas-Baquero, Virginia Nieto-Romero, Francisco J Roman‐Rodriguez, María Fernández-García, María José Pino-Barrio, Fátima Rodríguez-Fornés, Begoña Díez, María García-Bravo, Susana Navarro et al. · 2016 · InTech eBooks
  24. Engineered Proteins for Controlling Gene Expression
    Charles A. Gersbach · 2010 · Elsevier eBooks
  25. Engineered Proteins for Controlling Gene Expression
    Charles A. Gersbach · 2012 · Elsevier eBooks
  26. Applications of CRISPR-Cas System in Tumor Biology
    Mengdan Ma, Yuchen Liu, Weiren Huang · 2021 · ONCOLOGIE
  27. Epigenetic Regulation in Autism
    Cyril Jayakumar Peter, Abraham Reichenberg, Schahram Akbarian · 2015 · Contemporary clinical neuroscience
  28. Gene Therapy for Cardiovascular Disease: Inserting New Genes, Regulating the Expression of Native Genes, and Correcting Genetic Defects
    Ion S. Jovin, Frank J. Giordano · 2007
  29. Precision Genome Surgery with Meganucleases: A Promising Biopharmaceutical for Gene Therapy
    Alfred M. Pingoud, George H. Silva, Wolfgang Wende · 2013 · Wiley eBooks
  30. MAKING CHLAMYDOMONAS REINHARDTII A BETTER MODEL ORGANISM: TACKLING THE INEFFICIENCY OF NUCLEAR TRANSGENE EXPRESSION AND IMPROVING METHODS FOR THE GENERATION AND CHARACTERIZATION OF INSERTIONAL MUTANT LIBRARIES
    Thomas M. Plucinak · 2013 · Lincoln (University of Nebraska)
  31. Precision Genetic Engineering
    Thiago Jonas Nakayama, Aluízio Borém, Lucimara Chiari, Hugo Bruno Correa Molinari, Alexandre Lima Nepomuceno · 2014
  32. Report on the Workshop “New Technologies in Stem Cell Research,” Society for Pediatric Research, San Francisco, California, April 29, 2006
    Jerry C. Cheng, Edwin M. Horwitz, Stanislav L. Karsten, Lorelei D. Shoemaker, Harley I. Kornblumc, Punam Malik, Kathleen M. Sakamoto · 2007 · Stem Cells
  33. Two Hands Make Light Work of Gene Modification
    Andrew C.G. Porter · 2005 · Rejuvenation Research
  34. Anemia and Gene Therapy — A Matter of Control
    Katherine A. High · 2005 · New England Journal of Medicine
  35. Characterization and Optimization of the CRISPR/Cas System for Applications in Genome Engineering
    ChieYu Lin · 2014 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  36. Genome Editing Goes Global
    Sarah Webb · 2011 · BioTechniques
  37. Further study of the rôle played by fluorine in the causation of disease.
    Leo Spira · 1952 · PubMed
  38. Biological role of conceptus derived factors during early pregnancy in ruminants
    Kelsey E. Brooks · 2016 · MOspace Institutional Repository (University of Missouri)
  39. A CyclinB2-Cas9 fusion promotes the homology-directed repair of double-strand breaks
    Manuel M. Vicente, Afonso Mendes, M. Jason de la Cruz, José R. Vicente, Vasco M. Barreto · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  40. Restriction Enzymes
    Mala Mani, Karthikeyan Kandavelou, Srinivasan Chandrasegaran · 2005 · Encyclopedia of Life Sciences
  41. Inhibiting POLQ-mediated alternative NHEJ enhances CRISPR/Cas9 mediated precise genome editing in CHO cells
    Chuanjie Wang, Ming Wang, Mengmeng Zhang, Yao Wang, Xinying Li, Chenghua Liu, Rongrong Fan, Yuanqiang Zheng, Beifen Shen, Zhaolin Sun et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  42. Advances in Lentiviral Vector-based Cell Therapy with Mesenchymal Stem Cells
    Lajos Baranyi, Boro Dropulić · 2012 · Humana Press eBooks
  43. Otimização e utilização de macroendonucleases quiméricas para tentativa de correção da distrofia muscular em modelo canino (GRMD)
    José Luiz Nogueira · 2011 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  44. Designing methods for error correction in gene fabrication
    Jason Y. Park · 2005 · DSpace@MIT (Massachusetts Institute of Technology)
  45. Mechanisms involved in target sequence recognition and integration of human LINE-1 retrotransposons
    Nora Zingler · 2005
  46. Computational approaches to understand interactions between zinc finger proteins and DNA
    Fengli Fu · 2010 · Iowa State University Digital Repository (Iowa State University)
  47. Function and application of TAL effectors
    Ting Li · 2014
  48. Exogenous and endogenous gene regulation for specific and efficient cancer gene therapy
    Willemijn M. Gommans · 2006 · University of Groningen research database (University of Groningen / Centre for Information Technology)
  49. Genome Engineering Technology and Its Application in Mammalian Cells
    Le Cong · 2014 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  50. Multiplexed CRISPR/Cas9 genome editing increases the efficacy of homologous-dependent repair of donor sequences in mammalian cells
    Ezio T. Fok, Clement Brian Penny, Musa M. Mhlanga, Marc S. Weinberg · 2015 · South African Journal of Science
  51. Improving Zinc Finger Nucleases - Strategies for Increasing Gene Editing Activities and Evaluating Off-Target Effects
    Cherie L. Ramirez · 2012 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  52. Application and Potential of Genome Engineering by Artificial Enzymes
    Wataru Nomura · 2015 · YAKUGAKU ZASSHI
  53. Current approaches for efficient genetic editing in human pluripotent stem cells
    Bipasha Mukherjee-Clavin, Mark J. Tomishima, Gabsang Lee · 2013 · Frontiers in Biology
  54. Current approaches to cutaneous gene therapy
    Martin Laimer, Christoph M. Lanschuetzer, Helmut Hintner, Johann Wolfgang Bauer · 2006 · Expert Review of Dermatology
  55. Zinc finger nucleases correct genes
    Graciela Flores · 2005 · Genome biology
  56. Cut-and-paste therapy fixes mouse haemophilia
    Janelle Weaver · 2011 · Nature
  57. Chromatin targets: reading and writing the cancer cell epigenome
    Fyodor D. Urnov · 2004 · Drug Discovery Today Disease Models
  58. Plant gene targeting and gene replacement: application to crop genetic improvement
    Xiaohui Zhang, Ye Zhibiao, Zhang Yu-yang, Zheng Hou, LI Han-xia · 2008 · Chinese Journal of Agricultural Biotechnology
  59. Targeted transposition of the Sleeping Beauty transposon using zinc finger proteins
    Katrin Voigt · 2011 · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver
  60. Less is More: Enzymes Inspiring the Breakthroughs alongside Shining on Engineered Genes, Genome Editing, and/or Transgenics
    Yue Zhang · 2012 · Enzyme Engineering
  61. Design and engineering of human TRAIL variants
    Albert Martinus Van der Sloot · 2006 · University of Groningen research database (University of Groningen / Centre for Information Technology)
  62. Gene therapy II : viral vectors and treatment modalities
    J. Wes Ulm · 2005 · Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
  63. Sequence-Specific DNA Detection Utilizing Custom-Designed Zinc Finger Proteins
    Aik Teong Ooi · 2007 · UA Campus Repository (The University of Arizona)
  64. Angefertigt mit Genehmigung der Mathematisch-Naturwissenschaftlichen Fakultät der
    Rheinischen Friedrich-Wilhelms-Universität Bonn · 2012
  65. Targeted Plasmid Integration into the Human Genome by Engineered Recombinases
    Charles A. Gersbach, Carlos F. Barbas · 2012 · Topics in current genetics
  66. The Mechanism of Precise Genome Engineering in Human Cells
    Yinan Kan · 2015 · University of Minnesota Digital Conservancy (University of Minnesota)
  67. Zinc finger nucleases: Custom enzymes for DNA engineering
    Andriy Tovkach · 2009 · ProQuest Demo Repository
  68. Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation
    San Francisco, Howard Hughes Medical · 2015
  69. Preface
    Theodore Friedmann · 2012 · Methods in enzymology on CD-ROM/Methods in enzymology
  70. Designer Zinc Finger Nuclease: A Versatile Tool for Genome Editing in Animals
    Kiran Lakkireddy, Sudhakar Podha, Krishna Satya A, Kuppuswamy N. Kasturi, K. R. S. Sambasiva Rao · 2014 · Research & Reviews: A Journal of Biotechnology
  71. Stem Cell Gene Therapy
    Brian R. Davis, Nicole L. Prokopishyn · 2009 · Elsevier eBooks
  72. NUCLEASE-MEDIATED TARGETED GENETIC CORRECTION
    Dieter C. Gruenert, Hamid Emamekhoo, R. Geoffrey Sargent · 2019 · WORLD SCIENTIFIC (EUROPE) eBooks
  73. rAAV vectors for gene targeting
    Toni Cathomen · 2005 · CRC Press eBooks
  74. Exogenously-introduced Homing Endonucleases Catalyze Double-stranded DNA Breaks in Aedes aegypti
    Brenna E. Traver · 2009 · VTechWorks (Virginia Tech)
  75. Designer Effectors for Editing and Regulating Complex Genomes
    Maximilian Müller, Tafadzwa Mlambo, Claudio Mussolino · 2017 · Springer eBooks
  76. Edição do gene TFAM pela engenharia CRISPR Cas9 em modelo bovino
    Vanessa Cristina de Oliveira Souza · 2017
  77. Elucidation of Mechanisms of Fetal Hemoglobin Regulation by CRISPR/Cas9 Mediated Genome Editing
    Matthew C. Canver · 2016 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  78. Edição de genes associados à produção de ácidos graxos em soja
    Débora Torres Alves Figueirêdo · 2017
  79. Site‐Directed Genome Modification with Engineered Zinc Finger Proteins
    Lauren Elizabeth Woodard, Daniel L. Galvan, Matthew H. Wilson · 2018 · Wiley eBooks
  80. CHD6 and the oxidative stress-induced DNA damage response
    Shaun Moore · 2018 · Libraries and Cultural Resources (University of Calgary)
  81. Genome Editing of MSCs as a Platform for Cell Therapy
    Krissanapong Manotham, Supreecha Chattong · 2018 · Methods in molecular biology
  82. Genome Editing and Differentiation of Embryonic Stem Cells
    Brian Rudolph Shy · 2017 · Figshare
  83. Studies in Trypsin as an Alarm Substance in Zebrafish
    Abdullah Alsrhani · 2018
  84. Cholesterol metabolism and statin effects on an FH class II LDL-receptor mutation.
    Linda Omer · 2018
  85. Immunization With Recombinant Myelin Oligodendrocyte Glycoprotein Identifies Autoreactive T Cells As A Limiting Factor In Autoreactive Germinal Center Maintenance
    Rajiv W. Jain · 2018 · Scholarship@Western (Western University)
  86. Inference of Networks from Large Datasets
    Qi Zhang, Congmin Xu, Peng Qiu · 2019 · Elsevier eBooks
  87. Introducing Point Mutations into Human Pluripotent Stem Cells Using Seamless Genome Editing
    Yu Wang, Andrew J. H. Smith, David C. Hay · 2020 · Journal of Visualized Experiments
  88. Genetic Manipulation of Human Embryonic Stem Cells
    Yoav Mayshar, Nissim Benvenisty · 2012 · Elsevier eBooks
  89. Stem Cell Gene Therapy
    Brian R. Davis, Nicole L. Prokopishyn · 2012 · Elsevier eBooks
  90. Optimized guide RNA selection recommendations for using sp Cas9 gene editing in human hematopoietic stem and progenitor cells
    Han J. M. P. Verhagen, Carlijn Kuijk, Anne M. Kokke, Laurens Rutgers, Santhe A. van der Meulen, Gerard J. van Mierlo, Carlijn Voermans, Emile van den Akker · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  91. A brief history and primer on genome editing
    Kiran Musunuru · 2021 · Elsevier eBooks
  92. Current Ex-Vivo Gene Therapy Technologies and Future Developments
    Chen-Hsien Su, Deniz Erol · 2012 · Springer eBooks
  93. Oligonucleotide-mediated gene editing of Apolipoprotein A-I
    Petra Disterer · 2008 · OpenGrey (Institut de l'Information Scientifique et Technique)
  94. Restriction Enzymes
    Mala Mani, Karthikeyan Kandavelou, Srinivasan Chandrasegaran · 2007 · Encyclopedia of Life Sciences
  95. Faculty Opinions recommendation of Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.
    Andy Groves · 2013 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  96. Faculty Opinions recommendation of Computational redesign of endonuclease DNA binding and cleavage specificity.
    Alfred M. Pingoud · 2006 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  97. Genetic analysis of synaptogenesis
    Cecilia S. Lu, David Van Vactor · 2020 · Elsevier eBooks
  98. Gene Targeting
    Michael M. Seidman, John H. Wilson · 2006 · Wiley-VCH eBooks
  99. Faculty Opinions recommendation of High-frequency modification of plant genes using engineered zinc-finger nucleases.
    Stacey L. Harmer · 2009 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  100. Historical Overview of Genome Editing from Bacteria to Higher Eukaryotes
    Marcello Maresca · 2022 · Wiley eBooks