Baltimore, David

NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

Taganov, K. D., Boldin, M. P., Chang, K.-J., & Baltimore, D. (2006) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationImmune Response and Inflammation

Cited by 4,317

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

Beg, A. A., & Baltimore, D. (1996) · Science

NF-κB Signaling PathwaysCell death mechanisms and regulation

Cited by 3,047

Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses

BALTIMORE, D. (1970) · Nature

T-cell and Retrovirus StudiesViral-associated cancers and disorders

Cited by 2,068

MicroRNA-155 is induced during the macrophage inflammatory response

O'Connell, R. M., Taganov, K. D., Boldin, M. P., Cheng, G., & Baltimore, D. (2007) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationImmune Response and Inflammation

Cited by 1,866

ATR disruption leads to chromosomal fragmentation and early embryonic lethality

Brown, E. J., & Baltimore, D. (2000) · Genes & Development

DNA Repair MechanismsDevelopmental Biology and Gene Regulation

Cited by 951

Modular binding domains in signal transduction proteins

Cohen, G. B., Ren, R., & Baltimore, D. (1995) · Cell

Protein Kinase Regulation and GTPase SignalingReceptor Mechanisms and Signaling

Cited by 951

Circuitry of nuclear factor κB signaling

Hoffmann, A., & Baltimore, D. (2006) · Immunological Reviews

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 907

MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development

O'Connell, R. M., Kahn, D., Gibson, W. S. J., Round, J. L., Scholz, R. L., Chaudhuri, A. A., Kahn, M. E., Rao, D. S., & Baltimore, D. (2010) · Immunity

MicroRNA in disease regulationT-cell and B-cell Immunology

Cited by 889

miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice

Boldin, M. P., Taganov, K. D., Rao, D. S., Yang, L., Zhao, J. L., Kalwani, M., Garcia-Flores, Y., Luong, M., Devrekanli, A., Xu, J., et al. (2011) · Journal of Experimental Medicine

MicroRNA in disease regulationImmune Response and Inflammation

Cited by 861

Inositol phosphatase SHIP1 is a primary target of miR-155

O'Connell, R. M., Chaudhuri, A. A., Rao, D. S., & Baltimore, D. (2009) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationT-cell and B-cell Immunology

Cited by 826

Chimeric nucleases stimulate gene targeting in human cells

Porteus, M. H., & Baltimore, D. (2003) · Science

CRISPR and Genetic EngineeringDNA Repair Mechanisms

Cited by 741

Ordered rearrangement of immunoglobulin heavy chain variable region segments

Alt, F. W., Yancopoulos, G. D., Blackwell, T. K., Wood, C., Thomas, E., Boss, M., Coffman, R., Rosenberg, N., Tonegawa, S., & Baltimore, D. (1984) · The EMBO Journal

T-cell and B-cell ImmunologyDNA Repair Mechanisms

Cited by 733

A prudent path forward for genomic engineering and germline gene modification

Baltimore, D., Berg, P., Botchan, M., Carroll, D., Charo, R. A., Church, G., Corn, J. E., Daley, G. Q., Doudna, J. A., Fenner, M., et al. (2015) · Science

CRISPR and Genetic EngineeringBiomedical Ethics and Regulation

Cited by 733

MicroRNAs as regulatory elements in immune system logic

Mehta, A., & Baltimore, D. (2016) · Nature Reviews Immunology

MicroRNA in disease regulationT-cell and B-cell Immunology

Cited by 704

Cloned Poliovirus Complementary DNA Is Infectious in Mammalian Cells

Racaniello, V. R., & Baltimore, D. (1981) · Science

Viral Infections and Immunology ResearchVirology and Viral Diseases

Cited by 696

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

O'Connell, R. M., Rao, D. S., Chaudhuri, A. A., Boldin, M. P., Taganov, K. D., Nicoll, J., Paquette, R. L., & Baltimore, D. (2008) · The Journal of Experimental Medicine

MicroRNA in disease regulationAcute Myeloid Leukemia Research

Cited by 681

A detailed model of reverse transcription and tests of crucial aspects

Gilboa, E., Mitra, S. W., Goff, S., & Baltimore, D. (1979) · Cell

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 612

Antibody-based protection against HIV infection by vectored immunoprophylaxis

Balazs, A. B., Chen, J., Hong, C. M., Rao, D. S., Yang, L., & Baltimore, D. (2012) · Nature

HIV Research and TreatmentVirus-based gene therapy research

Cited by 545

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

Brown, E. J., & Baltimore, D. (2003) · Genes & Development

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 511

Gene conversion: some implications for immunoglobulin genes

Baltimore, D. (1981) · Cell

DNA Repair MechanismsT-cell and B-cell Immunology

Cited by 486

The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules

Hao, S., & Baltimore, D. (2009) · Nature Immunology

RNA Research and SplicingImmune Response and Inflammation

Cited by 480

Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages

Haldar, M., Kohyama, M., So, A. Y.-L., KC, W., Wu, X., Briseño, C. G., Satpathy, A. T., Kretzer, N. M., Arase, H., Rajasekaran, N. S., et al. (2014) · Cell

Iron Metabolism and DisordersPhagocytosis and Immune Regulation

Cited by 431

The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers.

Fujita, T., Nolan, G. P., Liou, H. C., Scott, M. L., & Baltimore, D. (1993) · Genes & Development

NF-κB Signaling PathwaysGenomics and Chromatin Dynamics

Cited by 409

NF-κB dysregulation in microRNA-146a–deficient mice drives the development of myeloid malignancies

Zhao, J. L., Rao, D. S., Boldin, M. P., Taganov, K. D., O'Connell, R. M., & Baltimore, D. (2011) · Proceedings of the National Academy of Sciences

NF-κB Signaling PathwaysMicroRNA in disease regulation

Cited by 386