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Cited by 5,102

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana

Alonso, José M., Stepanova, Anna N., Leisse, Thomas J., Kim, Christopher J., Chen, Huaming, Shinn, Paul, Stevenson, Denise K., Zimmerman, Justin, Barajas, Pascual, Cheuk, Rosa, Gadrinab, Carmelita, Heller, Collen, Jeske, Albert, Koesema, Eric, Meyers, Cristina C., Parker, Holly, Prednis, Lance, Ansari, Yasser, Choy, Nathan, Deen, Hashim, Geralt, Michael, Hazari, Nisha, Hom, Emily, Karnes, Meagan, Mulholland, Celene, Ndubaku, Ral, Schmidt, Ian, Guzman, Plinio, Aguilar-Henonin, Laura, Schmid, Markus, Weigel, Detlef, Carter, David E., Marchand, Trudy, Risseeuw, Eddy, Brogden, Debra, Zeko, Albana, Crosby, William L., Berry, Charles C., Ecker, Joseph R.·2003·Science

Abstract

Over 225,000 independent Agrobacterium transferred DNA (T-DNA) insertion events in the genome of the reference plant Arabidopsis thaliana have been created that represent near saturation of the gene space. The precise locations were determined for more than 88,000 T-DNA insertions, which resulted in the identification of mutations in more than 21,700 of the ∼29,454 predicted Arabidopsis genes. Genome-wide analysis of the distribution of integration events revealed the existence of a large integration site bias at both the chromosome and gene levels. Insertion mutations were identified in genes that are regulated in response to the plant hormone ethylene.

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Metadata

Authors
Alonso, J. M., Stepanova, A. N., Leisse, T. J., Kim, C. J., Chen, H., Shinn, P., Stevenson, D. K., Zimmerman, J., Barajas, P., Cheuk, R., Gadrinab, C., Heller, C., Jeske, A., Koesema, E., Meyers, C. C., Parker, H., Prednis, L., Ansari, Y., Choy, N., Deen, H., Geralt, M., Hazari, N., Hom, E., Karnes, M., Mulholland, C., Ndubaku, R., Schmidt, I., Guzman, P., Aguilar-Henonin, L., Schmid, M., Weigel, D., Carter, D. E., Marchand, T., Risseeuw, E., Brogden, D., Zeko, A., Crosby, W. L., Berry, C. C., & Ecker, J. R.
Venue
Science
Published
2003-08
Volume
301
Issue
5633
Pages
653-657
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2098115340
Cited by
5,102
References
3
FWCI
299.40
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana. https://app.cochat.ai/papers/10.1126/science.1086391
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Alonso, J. M., Stepanova, A. N., Leisse, T. J., Kim, C. J., Chen, H., Shinn, P., Stevenson, D. K., Zimmerman, J., Barajas, P., Cheuk, R., Gadrinab, C., Heller, C., Jeske, A., Koesema, E., Meyers, C. C., Parker, H., Prednis, L., Ansari, Y., Choy, N., . . . Ecker, J. R. (2003). Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana. Science. https://doi.org/10.1126/science.1086391

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.