The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Gene Expression Profiles in the Brain Predict Behavior in Individual Honey Bees
Abstract
We show that the age-related transition by adult honey bees from hive work to foraging is associated with changes in messenger RNA abundance in the brain for 39% of ∼5500 genes tested.This result, discovered using a highly replicated experimental design involving 72 microarrays, demonstrates more extensive genomic plasticity in the adult brain than has yet been shown.Experimental manipulations that uncouple behavior and age revealed that messenger RNA changes were primarily associated with behavior.Individual brain messenger RNA profiles correctly predicted the behavior of 57 out of 60 bees, indicating a robust association between brain gene expression in the individual and naturally occurring behavioral plasticity.
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“Many studies have found significant, predictable, and specific changes in brain gene expression profiles associated with behavioral responses to particular environmental stimuli (7–14).”
From Behavior-related gene regulatory networks: A new level of organization in the brain (2020) · cites this paper as [7]
In the citing paper
“Gene expression profiles in specific brain regions or even whole brains have proven useful as surrogates for behavioral states (Fig. 1A); in some cases, the correspondence between brain gene expression profile and behavior is strong enough to use the former to predict the latter (7, 27).”
From Behavior-related gene regulatory networks: A new level of organization in the brain (2020) · cites this paper as [7]
In the citing paper
“Organisms also show transitions from one distinct behavior to another. In some cases, each behavior is performed briefly, while in other cases each behavior is performed for a relatively long time period, giving rise to “behavioral states” (7).”
From Behavior-related gene regulatory networks: A new level of organization in the brain (2020) · cites this paper as [7]
Citations
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Cited by
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Social environment is associated with gene regulatory variation in the rhesus macaque immune system
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An evolutionary framework for studying mechanisms of social behavior
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Metadata
- Authors
- Whitfield, C. W., Cziko, A.-M., & Robinson, G. E.
- Affiliations
- Department of Entomology, University of Illinois at Urbana-Champaign, 320 Morrill Hall, 505 South Goodwin Avenue, Urbana, IL 61801, USA.
- Venue
- Science
- Published
- 2003-10-10
- Volume
- 302
- Issue
- 5643
- Pages
- 296-299
- ISSN
- 0036-8075
- 1095-9203
- Cited by
- 527
- References
- 23
- Language
- en
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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