The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Toxins-Antitoxins: Plasmid Maintenance, Programmed Cell Death, and Cell Cycle Arrest
Abstract
Antibiotic resistance, virulence, and other plasmids in bacteria use toxin-antitoxin gene pairs to ensure their persistence during host replication. The toxin-antitoxin system eliminates plasmid-free cells that emerge as a result of segregation or replication defects and contributes to intra- and interspecies plasmid dissemination. Chromosomal homologs of toxin-antitoxin genes are widely distributed in pathogenic and other bacteria and induce reversible cell cycle arrest or programmed cell death in response to starvation or other adverse conditions. The dissection of the interaction of the toxins with intracellular targets and the elucidation of the tertiary structures of toxin-antitoxin complexes have provided exciting insights into toxin-antitoxin behavior.
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Kobayashi, I. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.18.3742 · Cited by 513
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Persister cells, dormancy and infectious disease
Lewis, K. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1557 · Cited by 2,052
Environmental pollution by antibiotics and by antibiotic resistance determinants
Martinez, J. L. (2009) · Environmental Pollution · doi:10.1016/j.envpol.2009.05.051 · Cited by 1,912
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Metadata
- Authors
- Hayes, F.
- Venue
- Science
- Published
- 2003-09-12
- Volume
- 301
- Issue
- 5639
- Pages
- 1496-1499
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2081541337
- Cited by
- 583
- References
- 1
- FWCI
- 11.55
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
