The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Illuminating the Evolutionary History of Chlamydiae
Abstract
Chlamydiae are the major cause of preventable blindness and sexually transmitted disease. Genome analysis of a chlamydia-related symbiont of free-living amoebae revealed that it is twice as large as any of the pathogenic chlamydiae and had few signs of recent lateral gene acquisition. We showed that about 700 million years ago the last common ancestor of pathogenic and symbiotic chlamydiae was already adapted to intracellular survival in early eukaryotes and contained many virulence factors found in modern pathogenic chlamydiae, including a type III secretion system. Ancient chlamydiae appear to be the originators of mechanisms for the exploitation of eukaryotic cells.
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Cites
Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants
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Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis
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rRNA Operon Copy Number Reflects Ecological Strategies of Bacteria
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Amelioration of Bacterial Genomes: Rates of Change and Exchange
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Comparative genomes of Chlamydia pneumoniae and C. trachomatis
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Genes Lost and Genes Found: Evolution of Bacterial Pathogenesis and Symbiosis
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Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells
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Cited by
Sequence and structural analysis of BTB domain proteins
Stogios, P. J., Downs, G. S., Jauhal, J. J., Nandra, S. K., & Privé, G. G. (2005) · Genome Biology · doi:10.1186/gb-2005-6-10-r82 · Cited by 694
Amoebae as Training Grounds for Intracellular Bacterial Pathogens
Molmeret, M., Horn, M., Wagner, M., Santic, M., & Abu Kwaik, Y. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.1.20-28.2005 · Cited by 555
Self-citationBiased gene transfer in microbial evolution
Andam, C. P., & Gogarten, J. P. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2593 · Cited by 172
Assessing the bacterial contribution to the plastid proteome
Qiu, H., Price, D. C., Weber, A. P. M., Facchinelli, F., Yoon, H. S., & Bhattacharya, D. (2013) · Trends in Plant Science · doi:10.1016/j.tplants.2013.09.007 · Cited by 62
Metadata
- Authors
- Horn, M., Collingro, A., Schmitz-Esser, S., Beier, C. L., Purkhold, U., Fartmann, B., Brandt, P., Nyakatura, G. J., Droege, M., Frishman, D., Rattei, T., Mewes, H.-W., & Wagner, M.
- Venue
- Science
- Published
- 2004-04-30
- Volume
- 304
- Issue
- 5671
- Pages
- 728-730
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2100249322
- Cited by
- 420
- References
- 20
- FWCI
- 30.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- Horn, M., Collingro, A., Schmitz-Esser, S., Beier, C. L., Purkhold, U., Fartmann, B., Brandt, P., Nyakatura, G. J., Droege, M., Frishman, D., Rattei, T., Mewes, H.-W., & Wagner, M. (2004). Illuminating the Evolutionary History of Chlamydiae. Science. https://doi.org/10.1126/science.1096330
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
