The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Microbial Factor-Mediated Development in a Host-Bacterial Mutualism
Abstract
Tracheal cytotoxin (TCT), a fragment of the bacterial surface molecule peptidoglycan (PGN), is the factor responsible for the extensive tissue damage characteristic of whooping cough and gonorrhea infections. Here, we report that Vibrio fischeri also releases TCT, which acts in synergy with lipopolysaccharide (LPS) to trigger tissue development in its mutualistic symbiosis with the squid Euprymna scolopes . As components of PGN and LPS have commonly been linked with pathogenesis in animals, these findings demonstrate that host interpretation of these bacterial signal molecules is context dependent. Therefore, such differences in interpretation can lead to either inflammation and disease or to the establishment of a mutually beneficial animal-microbe association.
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Cites
Decoding the Patterns of Self and Nonself by the Innate Immune System
Medzhitov, R., & Janeway, C. A. (2002) · Science · doi:10.1126/science.1068883 · Cited by 2,154
The winnowing: establishing the squid–vibrio symbiosis.
Nyholm, S. V., & McFall-Ngai, M. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro957 · Cited by 803
Self-citationBacterial contributions to mammalian gut development
Hooper, L. (2004) · Trends in Microbiology · doi:10.1016/j.tim.2004.01.001 · Cited by 541
Cited by
The gut microbiota--masters of host development and physiology
Sommer, F., & Bäckhed, F. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro2974 · Cited by 3,681
The Sleep-Immune Crosstalk in Health and Disease
Besedovsky, L., Lange, T., & Haack, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00010.2018 · Cited by 1,479
“, free fatty acids, oxidized lipoproteins) and commensal bacteria representing a source of PAMPs [sometimes also described with the more global term microbe-associated molecular patterns (MAMPs), as they are not necessarily pathogenic] (189, 240, 244, 295, 329, 347).”
BackgroundGut immune maturation depends on colonization with a host-specific microbiota
Chung, H., Pamp, S. J., Hill, J. A., Surana, N. K., Edelman, S. M., Troy, E. B., Reading, N. C., Villablanca, E. J., Wang, S., Mora, J. R., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.037 · Cited by 1,241
Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
Bouskra, D., Brézillon, C., Bérard, M., Werts, C., Varona, R., Boneca, I. G., & Eberl, G. (2008) · Nature · doi:10.1038/nature07450 · Cited by 1,107
Targeting Toll-like receptors: emerging therapeutics?
Hennessy, E. J., Parker, A. E., & O'Neill, L. A. J. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd3203 · Cited by 886
Metadata
- Authors
- Koropatnick, T. A., Engle, J. T., Apicella, M. A., Stabb, E. V., Goldman, W. E., & McFall-Ngai, M. J.
- Venue
- Science
- Published
- 2004-11-12
- Volume
- 306
- Issue
- 5699
- Pages
- 1186-1188
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2002088088
- Cited by
- 378
- References
- 3
- FWCI
- 3.78
- Type
- journal article
- Language
- en
- Open access
- closed
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