The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Aging in Rhesus Monkeys: Relevance to Human Health Interventions
Abstract
Progress in gerontological research has been promoted through the use of numerous animal models, which have helped identify possible mechanisms of aging and age-related chronic diseases and evaluate possible interventions with potential relevance to human aging and disease. Further development of nonhuman primate models, particularly rhesus monkeys, could accelerate this progress, because their closer genetic relationship to humans produces a highly similar aging phenotype. Because the relatively long lives of primates increase the administrative and economic demands on research involving them, new emphasis has emerged on increasing the efficient use of these valuable resources through cooperative, interdisciplinary research.
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Cites
The retardation of aging and disease by dietary restriction
(1989) · Choice Reviews Online · doi:10.5860/choice.26-5101 · Cited by 1,476
Oliver, W. R., Shenk, J. L., Snaith, M. R., Russell, C. S., Plunket, K. D., Bodkin, N. L., Lewis, M. C., Winegar, D. A., Sznaidman, M. L., Lambert, M. H., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.091021198 · Cited by 1,046
Biomarkers of Caloric Restriction May Predict Longevity in Humans
Roth, G. S., Lane, M. A., Ingram, D. K., Mattison, J. A., Elahi, D., Tobin, J. D., Muller, D., & Metter, E. J. (2002) · Science · doi:10.1126/science.1071851 · Cited by 447
Self-citationAltered cytokine production in the elderly
Rink, L., Cakman, I., & Kirchner, H. (1998) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(97)00153-x · Cited by 378
Cyclic Estrogen Replacement Improves Cognitive Function in Aged Ovariectomized Rhesus Monkeys
Rapp, P. R., Morrison, J. H., & Roberts, J. A. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-13-05708.2003 · Cited by 351
Age-related Dendritic and Spine Changes in Corticocortically Projecting Neurons in Macaque Monkeys
Duan, H. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.9.950 · Cited by 316
Lane, M. A., Baer, D. J., Rumpler, W. V., Weindruch, R., Ingram, D. K., Tilmont, E. M., Cutler, R. G., & Roth, G. S. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.9.4159 · Cited by 313
Self-citationGrondin, R., Zhang, Z., Yi, A., Cass, W. A., Maswood, N., Andersen, A. H., Elsberry, D. D., Klein, M. C., Gerhardt, G. A., & Gash, D. M. (2002) · Brain · doi:10.1093/brain/awf234 · Cited by 283
Small, S. A., Chawla, M. K., Buonocore, M., Rapp, P. R., & Barnes, C. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400285101 · Cited by 280
Calorie restriction in rhesus monkeys
Mattison, J. (2003) · Experimental Gerontology · doi:10.1016/s0531-5565(02)00146-8 · Cited by 255
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Cited by
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
Mattison, J. A., Roth, G. S., Beasley, T. M., Tilmont, E. M., Handy, A. M., Herbert, R. L., Longo, D. L., Allison, D. B., Young, J. E., Bryant, M., et al. (2012) · Nature · doi:10.1038/nature11432 · Cited by 1,145
Self-citationCalorie restriction, SIRT1 and metabolism: understanding longevity
Bordone, L., & Guarente, L. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1616 · Cited by 1,020
Heilbronn, L. K., de Jonge, L., Frisard, M. I., DeLany, J. P., Larson-Meyer, D. E., Rood, J., Nguyen, T., Martin, C. K., Volaufova, J., Most, M. M., et al. (2006) · JAMA · doi:10.1001/jama.295.13.1539 · Cited by 969
Kregel, K. C., & Zhang, H. J. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00327.2006 · Cited by 883
Metabolism and Circadian Rhythms—Implications for Obesity
Froy, O. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0014 · Cited by 505
Metadata
- Authors
- Roth, G. S., Mattison, J. A., Ottinger, M. A., Chachich, M. E., Lane, M. A., & Ingram, D. K.
- Venue
- Science
- Published
- 2004-09-03
- Volume
- 305
- Issue
- 5689
- Pages
- 1423-1426
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2131913960
- Cited by
- 353
- References
- 41
- FWCI
- 8.59
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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