Metabolism and Circadian Rhythms—Implications for Obesity

Positional cloning of the mouse obese gene and its human homologue

Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419 · see citing works

Central nervous system control of food intake

Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451 · see citing works

Leptin and the regulation of body weight in mammals

Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405 · see citing works

Coordination of circadian timing in mammals

Reppert, S. M., & Weaver, D. R. (2002) · Nature · doi:10.1038/nature00965 · Cited by 4,379 · see citing works

Impact of sleep debt on metabolic and endocrine function

Spiegel, K., Leproult, R., & Van Cauter, E. (1999) · The Lancet · doi:10.1016/s0140-6736(99)01376-8 · Cited by 3,672 · see citing works

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Cantó, C., Gerhart-Hines, Z., Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P., & Auwerx, J. (2009) · Nature · doi:10.1038/nature07813 · Cited by 3,300 · see citing works

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

Huszar, D., Lynch, C. A., Fairchild-Huntress, V., Dunmore, J. H., Fang, Q., Berkemeier, L. R., Gu, W., Kesterson, R. A., Boston, B. A., Cone, R. D., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)81865-6 · Cited by 3,030 · see citing works

Congenital leptin deficiency is associated with severe early-onset obesity in humans

Montague, C. T., Farooqi, I. S., Whitehead, J. P., Soos, M. A., Rau, H., Wareham, N. J., Sewter, C. P., Digby, J. E., Mohammed, S. N., Hurst, J. A., et al. (1997) · Nature · doi:10.1038/43185 · Cited by 2,936 · see citing works

Molecular Bases for Circadian Clocks

Dunlap, J. C. (1999) · Cell · doi:10.1016/s0092-8674(00)80566-8 · Cited by 2,900 · see citing works

Hypothalamic regulation of sleep and circadian rhythms

Saper, C. B., Scammell, T. E., & Lu, J. (2005) · Nature · doi:10.1038/nature04284 · Cited by 2,804 · see citing works

The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

Lin, L., Faraco, J., Li, R., Kadotani, H., Rogers, W., Lin, X., Qiu, X., de Jong, P. J., Nishino, S., & Mignot, E. (1999) · Cell · doi:10.1016/s0092-8674(00)81965-0 · Cited by 2,613 · see citing works

Obesity and Metabolic Syndrome in Circadian <i>Clock</i> Mutant Mice

Turek, F. W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D. R., et al. (2005) · Science · doi:10.1126/science.1108750 · Cited by 2,485 · see citing works

Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index

Taheri, S., Lin, L., Austin, D., Young, T., & Mignot, E. (2004) · PLoS Medicine · doi:10.1371/journal.pmed.0010062 · Cited by 2,477 · see citing works

Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite

Spiegel, K., Tasali, E., Penev, P., & Cauter, E. V. (2004) · Annals of Internal Medicine · doi:10.7326/0003-4819-141-11-200412070-00008 · Cited by 2,459 · see citing works

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., & Schibler, U. (2000) · Genes &amp; Development · doi:10.1101/gad.183500 · Cited by 2,394 · see citing works

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

Cowley, M. A., Smart, J. L., Rubinstein, M., Cerdán, M. G., Diano, S., Horvath, T. L., Cone, R. D., & Low, M. J. (2001) · Nature · doi:10.1038/35078085 · Cited by 2,356 · see citing works

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

Clément, K., Vaisse, C., Lahlou, N., Cabrol, S., Pelloux, V., Cassuto, D., Gourmelen, M., Dina, C., Chambaz, J., Lacorte, J.-M., et al. (1998) · Nature · doi:10.1038/32911 · Cited by 2,346 · see citing works

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Yoo, S.-H., Yamazaki, S., Lowrey, P. L., Shimomura, K., Ko, C. H., Buhr, E. D., Siepka, S. M., Hong, H.-K., Oh, W. J., Yoo, O. J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308709101 · Cited by 2,329 · see citing works

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

Preitner, N., Damiola, F., Luis-Lopez-Molina, Zakany, J., Duboule, D., Albrecht, U., & Schibler, U. (2002) · Cell · doi:10.1016/s0092-8674(02)00825-5 · Cited by 2,198 · see citing works

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

Fan, W., Boston, B. A., Kesterson, R. A., Hruby, V. J., & Cone, R. D. (1997) · Nature · doi:10.1038/385165a0 · Cited by 1,902 · see citing works

Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

Ollmann, M. M., Wilson, B. D., Yang, Y.-K., Kerns, J. A., Chen, Y., Gantz, I., & Barsh, G. S. (1997) · Science · doi:10.1126/science.278.5335.135 · Cited by 1,881 · see citing works

Resetting of circadian time in peripheral tissues by glucocorticoid signaling

Balsalobre, A., Brown, S. A., Marcacci, L., Tronche, F., Kellendonk, C., Reichardt, H. M., Schütz, G., & Schibler, U. (2000) · Science · doi:10.1126/science.289.5488.2344 · Cited by 1,859 · see citing works

Entrainment of the circadian clock in the liver by feeding

Stokkan, K.-A., Yamazaki, S., Tei, H., Sakaki, Y., & Menaker, M. (2001) · Science · doi:10.1126/science.291.5503.490 · Cited by 1,800 · see citing works

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

Krude, H., Biebermann, H., Luck, W., Horn, R., Brabant, G. E., & Grüters, A. (1998) · Nature Genetics · doi:10.1038/509 · Cited by 1,719 · see citing works

Mutagenesis and Mapping of a Mouse Gene, <i>Clock</i> , Essential for Circadian Behavior

Vitaterna, M. H., King, D. P., Chang, A.-M., Kornhauser, J. M., Lowrey, P. L., McDonald, J. D., Dove, W. F., Pinto, L. H., Turek, F. W., & Takahashi, J. S. (1994) · Science · doi:10.1126/science.8171325 · Cited by 1,632 · see citing works

Anatomy and regulation of the central melanocortin system

Cone, R. D. (2005) · Nature Neuroscience · doi:10.1038/nn1455 · Cited by 1,583 · see citing works

Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight

Kalra, S. P., Dube, M. G., Pu, S., Xu, B., Horváth, T. L., & Kalra, P. S. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.1.0357 · Cited by 1,556 · see citing works

Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight

Kalra, S. P. (1999) · Endocrine Reviews · doi:10.1210/er.20.1.68 · Cited by 1,554 · see citing works

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms.

Welsh, D. K., Logothetis, D., Meister, M., & Reppert, S. (1995) · Neuron · doi:10.1016/0896-6273(95)90214-7 · Cited by 1,535 · see citing works

High-Fat Diet Disrupts Behavioral and Molecular Circadian Rhythms in Mice

Kohsaka, A., Laposky, A. D., Ramsey, K. M., Estrada, C., Joshu, C., Kobayashi, Y., Turek, F. W., & Bass, J. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.09.006 · Cited by 1,528 · see citing works

Extensive and divergent circadian gene expression in liver and heart

Storch, K.-F., Lipan, O., Leykin, I., Viswanathan, N., Davis, F. C., Wong, W. H., & Weitz, C. J. (2002) · Nature · doi:10.1038/nature744 · Cited by 1,509 · see citing works

The role of neuropeptide Y in the antiobesity action of the obese gene product

Stephens, T. W., Basinski, M., Bristow, P. K., Bue-Valleskey, J. M., Burgett, S. G., Craft, L., Hale, J., Hoffmann, J., Hsiung, H. M., Kriauciunas, A., et al. (1995) · Nature · doi:10.1038/377530a0 · Cited by 1,498 · see citing works

The Sir2 Family of Protein Deacetylases

Blander, G., & Guarente, L. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073651 · Cited by 1,496 · see citing works

Molecular analysis of mammalian circadian rhythms

Reppert, S. M., & Weaver, D. R. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.647 · Cited by 1,444 · see citing works

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

Nakahata, Y., Kaluzova, M., Grimaldi, B., Sahar, S., Hirayama, J., Chen, D., Guarente, L. P., & Sassone-Corsi, P. (2008) · Cell · doi:10.1016/j.cell.2008.07.002 · Cited by 1,427 · see citing works

Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity

Hara, J., Beuckmann, C. T., Nambu, T., Willie, J. T., Chemelli, R. M., Sinton, C. M., Sugiyama, F., Yagami, K.-I., Goto, K., Yanagisawa, M., et al. (2001) · Neuron · doi:10.1016/s0896-6273(01)00293-8 · Cited by 1,401 · see citing works

SIRT1 regulates circadian clock gene expression through PER2 deacetylation

Asher, G., Gatfield, D., Stratmann, M., Reinke, H., Dibner, C., Kreppel, F., Mostoslavsky, R., Alt, F. W., & Schibler, U. (2008) · Cell · doi:10.1016/j.cell.2008.06.050 · Cited by 1,376 · see citing works

The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA Damage Response In Vivo

Fu, L., Pelicano, H., Liu, J., Huang, P., & Lee, C. C. (2002) · Cell · doi:10.1016/s0092-8674(02)00961-3 · Cited by 1,256 · see citing works

Circadian Control of the NAD ⁺ Salvage Pathway by CLOCK-SIRT1

Nakahata, Y., Sahar, S., Astarita, G., Kaluzova, M., & Sassone-Corsi, P. (2009) · Science · doi:10.1126/science.1170803 · Cited by 1,198 · see citing works

Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock

Kondratov, R. V., Kondratova, A. A., Gorbacheva, V. Y., Vykhovanets, O. V., & Antoch, M. P. (2006) · Genes &amp; Development · doi:10.1101/gad.1432206 · Cited by 1,188 · see citing works

From Lesions to Leptin

Elmquist, J. K., Elias, C. F., & Saper, C. B. (1999) · Neuron · doi:10.1016/s0896-6273(00)81084-3 · Cited by 1,160 · see citing works

A frameshift mutation in MC4R associated with dominantly inherited human obesity

Yeo, G. S. H., Farooqi, I. S., Aminian, S., Halsall, D. J., Stanhope, R. G., & O'Rahilly, S. (1998) · Nature Genetics · doi:10.1038/2404 · Cited by 1,159 · see citing works

Posttranslational Mechanisms Regulate the Mammalian Circadian Clock

Lee, C., Etchegaray, J., Cagampang, F. R. A., Loudon, A. S. I., & Reppert, S. M. (2001) · Cell · doi:10.1016/s0092-8674(01)00610-9 · Cited by 1,158 · see citing works

A leptin missense mutation associated with hypogonadism and morbid obesity

Strobel, A., Issad, T., Camoin, L., Ozata, M., & Strosberg, A. D. (1998) · Nature Genetics · doi:10.1038/ng0398-213 · Cited by 1,158 · see citing works

Mice lacking melanin-concentrating hormone are hypophagic and lean

Shimada, M., Tritos, N. A., Lowell, B. B., Flier, J. S., & Maratos–Flier, E. (1998) · Nature · doi:10.1038/25341 · Cited by 1,152 · see citing works

A Functional Genomics Strategy Reveals Rora as a Component of the Mammalian Circadian Clock

Sato, T. K., Panda, S., Miraglia, L. J., Reyes, T. M., Rudic, R. D., McNamara, P., Naik, K. A., FitzGerald, G. A., Kay, S. A., & Hogenesch, J. B. (2004) · Neuron · doi:10.1016/j.neuron.2004.07.018 · Cited by 1,115 · see citing works

A frameshift mutation in human MC4R is associated with a dominant form of obesity

Vaisse, C., Clément, K., Guy-grand, B., & Froguel, P. (1998) · Nature Genetics · doi:10.1038/2407 · Cited by 1,091 · see citing works

Expression of ghrelin receptor mRNA in the rat and the mouse brain

Zigman, J. M., Jones, J. E., Lee, C. E., Saper, C. B., & Elmquist, J. K. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.20823 · Cited by 1,074 · see citing works

BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis

Rudic, R. D., McNamara, P., Curtis, A.-M., Boston, R. C., Panda, S., Hogenesch, J. B., & FitzGerald, G. A. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020377 · Cited by 1,059 · see citing works

Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors

Rutter, J., Reick, M., Wu, L. C., & McKnight, S. L. (2001) · Science · doi:10.1126/science.1060698 · Cited by 1,059 · see citing works

Overview of caloric restriction and ageing

Masoro, E. J. (2005) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2005.03.012 · Cited by 1,054 · see citing works

Physiological significance of a peripheral tissue circadian clock

Lamia, K. A., Storch, K.-F., & Weitz, C. J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806717105 · Cited by 1,048 · see citing works

Circadian rhythms from flies to human

Panda, S., Hogenesch, J. B., & Kay, S. A. (2002) · Nature · doi:10.1038/417329a · Cited by 1,044 · see citing works

Elevation of Plasma Cytokines in Disorders of Excessive Daytime Sleepiness: Role of Sleep Disturbance and Obesity

Vgontzas, A. N., Papanicolaou, D. A., Bixler, E. O., Kales, A., Tyson, K., & Chrousos, G. P. (1997) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jcem.82.5.3950 · Cited by 974 · see citing works

Nuclear Receptor Expression Links the Circadian Clock to Metabolism

Yang, X., Downes, M., Yu, R. T., Bookout, A. L., He, W., Straume, M., Mangelsdorf, D. J., & Evans, R. M. (2006) · Cell · doi:10.1016/j.cell.2006.06.050 · Cited by 934 · see citing works

Association of sleep time with diabetes mellitus and impaired glucose tolerance

Gottlieb, D. J., Punjabi, N. M., Newman, A. B., Resnick, H. E., Redline, S., Baldwin, C. M., & Nieto, F. J. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.8.863 · Cited by 927 · see citing works

Leptin Differentially Regulates NPY and POMC Neurons Projecting to the Lateral Hypothalamic Area

Elias, C. F., Aschkenasi, C., Lee, C., Kelly, J., Ahima, R. S., Bjorbæk, C., Flier, J. S., Saper, C. B., & Elmquist, J. K. (1999) · Neuron · doi:10.1016/s0896-6273(01)80035-0 · Cited by 924 · see citing works

Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27 485 people

Karlsson, B., Knutsson, A., & Lindahl, B. (2001) · Occupational and Environmental Medicine · doi:10.1136/oem.58.11.747 · Cited by 924 · see citing works

The Meter of Metabolism

Green, C. B., Takahashi, J. S., & Bass, J. (2008) · Cell · doi:10.1016/j.cell.2008.08.022 · Cited by 902 · see citing works

Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity

Vaisse, C., Clement, K., Durand, E., Hercberg, S., Guy-Grand, B., & Froguel, P. (2000) · Journal of Clinical Investigation · doi:10.1172/jci9238 · Cited by 897 · see citing works

Circadian Regulator CLOCK Is a Histone Acetyltransferase

Doi, M., Hirayama, J., & Sassone‐Corsi, P. (2006) · Cell · doi:10.1016/j.cell.2006.03.033 · Cited by 890 · see citing works

Three period Homologs in Mammals: Differential Light Responses in the Suprachiasmatic Circadian Clock and Oscillating Transcripts Outside of Brain

Zylka, M. J., Shearman, L. P., Weaver, D. R., & Reppert, S. M. (1998) · Neuron · doi:10.1016/s0896-6273(00)80492-4 · Cited by 865 · see citing works

Circadian food-anticipatory activity: Formal models and physiological mechanisms

Mistlberger, R. E. (1994) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(94)90023-x · Cited by 857 · see citing works

A transcription factor response element for gene expression during circadian night

Ueda, H. R., Chen, W., Adachi, A. A., Wakamatsu, H., Hayashi, S., Takasugi, T., Nagano, M., Nakahama, K., Suzuki, Y., Sugano, S., et al. (2002) · Nature · doi:10.1038/nature00906 · Cited by 850 · see citing works

Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency

Farooqi, I. S., Yeo, G. S. H., Keogh, J. M., Aminian, S., Jebb, S. A., Butler, G. E., Cheetham, T. D., & O’Rahilly, S. (2000) · Journal of Clinical Investigation · doi:10.1172/jci9397 · Cited by 811 · see citing works

System-level identification of transcriptional circuits underlying mammalian circadian clocks

Ueda, H. R., Hayashi, S., Chen, W., Sano, M., Machida, M., Shigeyoshi, Y., Iino, M., & Hashimoto, S. (2005) · Nature Genetics · doi:10.1038/ng1504 · Cited by 786 · see citing works

Circadian Cycling of the Mouse Liver Transcriptome, as Revealed by cDNA Microarray, Is Driven by the Suprachiasmatic Nucleus

Akhtar, R. A., Reddy, A. B., Maywood, E. S., Clayton, J. D., King, V. M., Smith, A. G., Gant, T. W., Hastings, M. H., & Kyriacou, C. P. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00759-5 · Cited by 777 · see citing works

To Eat or to Sleep? Orexin in the Regulation of Feeding and Wakefulness

Willie, J. T., Chemelli, R. M., Sinton, C. M., & Yanagisawa, M. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.429 · Cited by 768 · see citing works

Caloric Intake and Aging

Weindruch, R. H., & Sohal, R. S. (1997) · New England Journal of Medicine · doi:10.1056/nejm199710023371407 · Cited by 743 · see citing works

Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake

Anson, R. M., Guo, Z., de Cabo, R., Iyun, T., Rios, M., Hagepanos, A., Ingram, D. K., Lane, M. A., & Mattson, M. P. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1035720100 · Cited by 732 · see citing works

Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression

Welsh, D. K., Yoo, S.-H., Liu, A. C., Takahashi, J. S., & Kay, S. A. (2004) · Current Biology · doi:10.1016/j.cub.2004.11.057 · Cited by 726 · see citing works

Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus

Cheng, M. Y., Bullock, C. M., Li, C., Lee, A. G., Bermak, J. C., Belluzzi, J., Weaver, D. R., Leslie, F. M., & Zhou, Q.-Y. (2002) · Nature · doi:10.1038/417405a · Cited by 715 · see citing works

Overweight and Obesity: Prevalence, Consequences, and Causes of a Growing Public Health Problem

Wyatt, S. B., Winters, K. P., & Dubbert, P. M. (2006) · The American Journal of the Medical Sciences · doi:10.1097/00000441-200604000-00002 · Cited by 697 · see citing works

Rhythmic histone acetylation underlies transcription in the mammalian circadian clock

Etchegaray, J.-P., Lee, C., Wade, P. A., & Reppert, S. M. (2003) · Nature · doi:10.1038/nature01314 · Cited by 679 · see citing works

The Association Between Short Sleep Duration and Obesity in Young Adults: a 13-Year Prospective Study

Hasler, G., Buysse, D. J., Klaghofer, R., Gamma, A., Ajdacic, V., Eich, D., Rössler, W., & Angst, J. (2004) · Sleep · doi:10.1093/sleep/27.4.661 · Cited by 672 · see citing works

The “other” circadian system: food as a Zeitgeber

Stephan, F. K. (2002) · Journal of Biological Rhythms · doi:10.1177/074873002129002591 · Cited by 672 · see citing works

Localization of a "Feeding Center" in the Hypothalamus of the Rat

Anand, B. K., & Brobeck, J. R. (1951) · Experimental Biology and Medicine · doi:10.3181/00379727-77-18766 · Cited by 670 · see citing works

System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock

Kornmann, B., Schaad, O., Bujard, H., Takahashi, J. S., & Schibler, U. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050034 · Cited by 658 · see citing works

Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism

Liu, C., Li, S., Liu, T., Borjigin, J., & Lin, J. D. (2007) · Nature · doi:10.1038/nature05767 · Cited by 643 · see citing works

Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function.

Ahima, R. S., Prabakaran, D., & Flier, J. S. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1176 · Cited by 627 · see citing works

Roles of Circadian Rhythmicity and Sleep in Human Glucose Regulation

Cauter, E. V., Polonsky, K. S., & Scheen, A. J. (1997) · Endocrine Reviews · doi:10.1210/edrv.18.5.0317 · Cited by 611 · see citing works

Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions

Ripperger, J. A., & Schibler, U. (2006) · Nature Genetics · doi:10.1038/ng1738 · Cited by 593 · see citing works

Melanopsin in cells of origin of the retinohypothalamic tract

Gooley, J. J., Lü, J., Chou, T. C., Scammell, T. E., & Saper, C. B. (2001) · Nature Neuroscience · doi:10.1038/nn768 · Cited by 586 · see citing works

Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms

Chou, T. C., Scammell, T. E., Gooley, J. J., Gaus, S. E., Saper, C. B., & Lu, J. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-33-10691.2003 · Cited by 576 · see citing works

A C-Terminal Fragment of Agouti-Related Protein Increases Feeding and Antagonizes the Effect of Alpha-Melanocyte Stimulating Hormone<i>in Vivo</i>

Rossi, M., Kim, M. S., Morgan, D. G. A., Small, C. J., Edwards, C. M. B., Sunter, D., Abusnana, S., Goldstone, A. P., Russell, S. H., Stanley, S. A., et al. (1998) · Endocrinology · doi:10.1210/endo.139.10.6332 · Cited by 576 · see citing works

The Molecular Clock Mediates Leptin-Regulated Bone Formation

Fu, L., Patel, M. S., Bradley, A., Wagner, E. F., & Karsenty, G. (2005) · Cell · doi:10.1016/j.cell.2005.06.028 · Cited by 575 · see citing works

Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus

Hara, R., Wan, K., Wakamatsu, H., Aida, R., Moriya, T., Akiyama, M., & Shibata, S. (2001) · Genes to Cells · doi:10.1046/j.1365-2443.2001.00419.x · Cited by 569 · cited 1× · see citing works

The VPAC2 Receptor Is Essential for Circadian Function in the Mouse Suprachiasmatic Nuclei

Harmar, A. J., Marston, H. M., Shen, S., Spratt, C., West, K. M., Sheward, W. J., Morrison, C. F., Dorin, J. R., Piggins, H. D., Reubi, J.-C., et al. (2002) · Cell · doi:10.1016/s0092-8674(02)00736-5 · Cited by 549 · see citing works

Circadian orchestration of the hepatic proteome

Reddy, A. B., Karp, N. A., Maywood, E. S., Sage, E. A., Deery, M., O'Neill, J. S., Wong, G. K. Y., Chesham, J., Odell, M., Lilley, K. S., et al. (2006) · Current Biology · doi:10.1016/j.cub.2006.04.026 · Cited by 548 · see citing works

Regulation of Daily Locomotor Activity and Sleep by Hypothalamic EGF Receptor Signaling

Kramer, A., Yang, F.-C., Snodgrass, P., Li, X., Scammell, T. E., Davis, F. C., & Weitz, C. J. (2001) · Science · doi:10.1126/science.1067716 · Cited by 536 · see citing works

Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis

Shimba, S., Ishii, N., Ohta, Y., Ohno, T., Watabe, Y., Hayashi, M., Wada, T., Aoyagi, T., & Tezuka, M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0502383102 · Cited by 536 · see citing works

The hypothalamic integrator for circadian rhythms

Saper, C. B., Lü, J., Chou, T. C., & Gooley, J. J. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2004.12.009 · Cited by 528 · see citing works

CLOCK-mediated acetylation of BMAL1 controls circadian function

Hirayama, J., Sahar, S., Grimaldi, B., Tamaru, T., Takamatsu, K., Nakahata, Y., & Sassone‐Corsi, P. (2007) · Nature · doi:10.1038/nature06394 · Cited by 525 · see citing works

Peripheral Circadian Oscillators in Mammals: Time and Food

Schibler, U., Ripperger, J. A., & Brown, S. A. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730403018003007 · Cited by 525 · see citing works

Cellular Construction of a Circadian Clock: Period Determination in the Suprachiasmatic Nuclei

Liu, C., Weaver, D. R., Strogatz, S. H., & Reppert, S. M. (1997) · Cell · doi:10.1016/s0092-8674(00)80473-0 · Cited by 508 · see citing works

Playing with bone and fat

Gimble, J. M., Zvonic, S., Floyd, Z. E., Kassem, M. S., & NUTTALL, M. E. (2006) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20777 · Cited by 505 · see citing works

Control of Mammalian Circadian Rhythm by CKIε-Regulated Proteasome-Mediated PER2 Degradation

Eide, E. J., Woolf, M. F., Kang, H., Woolf, P., Hurst, W., Camacho, F., Vielhaber, E. L., Giovanni, A., & Virshup, D. M. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.7.2795-2807.2005 · Cited by 495 · see citing works

Characterization of Peripheral Circadian Clocks in Adipose Tissues

Zvonic, S., Ptitsyn, A. A., Conrad, S. A., Scott, L. K., Floyd, Z. E., Kilroy, G. E., Wu, X., Goh, B. C. K., Mynatt, R. L., & Gimble, J. M. (2006) · Diabetes · doi:10.2337/diabetes.55.04.06.db05-0873 · Cited by 495 · see citing works

The orphan nuclear receptor RORα regulates circadian transcription of the mammalian core-clock Bmal1

Akashi, M., & Takumi, T. (2005) · Nature Structural & Molecular Biology · doi:10.1038/nsmb925 · Cited by 493 · see citing works

Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts

Balsalobre, A., Marcacci, L., & Schibler, U. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00758-2 · Cited by 485 · see citing works

Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway

Buijs, R. M., Wortel, J., Van Heerikhuize, J. J., Feenstra, M. G. P., Ter Horst, G. J., Romijn, H. J., & Kalsbeek, A. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00575.x · Cited by 485 · see citing works

Glucocorticoid hormones inhibit food‐induced phase‐shifting of peripheral circadian oscillators

Minh, N. L., Damiola, F., Tronche, F., Schütz, G., & Schibler, U. (2001) · The EMBO Journal · doi:10.1093/emboj/20.24.7128 · Cited by 467 · see citing works

Several Mutations in the Melanocortin-4 Receptor Gene Including a Nonsense and a Frameshift Mutation Associated with Dominantly Inherited Obesity in Humans

Hinney, A., Schmidt, A., Nottebom, K., Heibült, O., Becker, I., Ziegler, A., Gerber, G., Sina, M., Görg, T., Mayer, H. G., et al. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.4.5728 · Cited by 462 · see citing works

How does calorie restriction work?Preprint

Koubova, J., & Guarente, L. (2003) · Genes & Development · doi:10.1101/gad.1052903 · Cited by 457 · see citing works

The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms

Gooley, J. J., Schomer, A., & Saper, C. B. (2006) · Nature Neuroscience · doi:10.1038/nn1651 · Cited by 453 · see citing works

Biomarkers of Caloric Restriction May Predict Longevity in Humans

Roth, G. S., Lane, M. A., Ingram, D. K., Mattison, J. A., Elahi, D., Tobin, J. D., Muller, D. C., & Metter, E. J. (2002) · Science · doi:10.1126/science.1071851 · Cited by 448 · see citing works

Regulation of CLOCK and MOP4 by Nuclear Hormone Receptors in the Vasculature

McNamara, P., Seo, S., Rudic, R. D., Sehgal, A., Chakravarti, D., & FitzGerald, G. A. (2001) · Cell · doi:10.1016/s0092-8674(01)00401-9 · Cited by 441 · see citing works

Synchronization and Maintenance of Timekeeping in Suprachiasmatic Circadian Clock Cells by Neuropeptidergic Signaling

Maywood, E. S., Reddy, A. B., Wong, G. K. Y., O'Neill, J. S., O'Brien, J. A., McMahon, D. G., Harmar, A. J., Okamura, H., & Hastings, M. H. (2006) · Current Biology · doi:10.1016/j.cub.2006.02.023 · Cited by 438 · see citing works

Obesity and the Hypothalamus: Novel Peptides for New Pathways

Flier, J. S., & Maratos–Flier, E. (1998) · Cell · doi:10.1016/s0092-8674(00)80937-x · Cited by 430 · see citing works

A clock shock: mouse CLOCK is not required for circadian oscillator function

DeBruyne, J. P., Noton, E., Lambert, C. M., Maywood, E. S., Weaver, D. R., & Reppert, S. M. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.041 · Cited by 430 · see citing works

A dose–response relationship between short sleeping hours and childhood obesity: results of the Toyama Birth Cohort Study

Sekine, M., Yamagami, T., Handa, K., Saito, T., Nanri, S., Kawaminami, K., Tokui, N., Yoshida, K., & Kagamimori, S. (2002) · Child Care Health and Development · doi:10.1046/j.1365-2214.2002.00260.x · Cited by 418 · see citing works

Overweight and obese patients in a primary care population report less sleep than patients with a normal body mass index

Vorona, R. D., Winn, M. P., Babineau, T. W., Eng, B. P., Feldman, H. R., & Ware, J. C. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.1.25 · Cited by 405 · see citing works

Sirtuins: The ‘ <i>magnificent seven</i> ’, function, metabolism and longevity

Dali‐Youcef, N., Lagouge, M., Froelich, S., Koehl, C., Schoonjans, K., & Auwerx, J. (2007) · Annals of Medicine · doi:10.1080/07853890701408194 · Cited by 402 · see citing works

Metabolism and the Control of Circadian Rhythms

Rutter, J. P., Reick, M., & McKnight, S. L. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.090501.142857 · Cited by 401 · see citing works

Clock controls circadian period in isolated suprachiasmatic nucleus neurons

Herzog, E. D., Takahashi, J. S., & Block, G. D. (1998) · Nature Neuroscience · doi:10.1038/3708 · Cited by 387 · see citing works

Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity

Yıldız, B. O., Suchard, M. A., Wong, M., McCann, S. M., & Licinio, J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403465101 · Cited by 385 · see citing works

Melatonin, human aging, and age-related diseases

Karasek, M. (2004) · Experimental Gerontology · doi:10.1016/j.exger.2004.04.012 · Cited by 380 · see citing works

Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei

Elmquist, J. K., Ahima, R. S., Elias, C. F., Flier, J. S., & Saper, C. B. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.2.741 · Cited by 376 · see citing works

Identification of the circadian transcriptome in adult mouse skeletal muscle

McCarthy, J. J., Andrews, J. L., McDearmon, E. L., Campbell, K. S., Barber, B. K., Miller, B. H., Walker, J. R., Hogenesch, J. B., Takahashi, J. S., & Esser, K. A. (2007) · Physiological Genomics · doi:10.1152/physiolgenomics.00066.2007 · Cited by 363 · see citing works

Selective parasympathetic innervation of subcutaneous and intra-abdominal fat — functional implications

Kreier, F., Fliers, E., Voshol, P. J., van Eden, C. G., Havekes, L. M., Kalsbeek, A., Heijningen, C. L. V., Sluiter, A. A., Mettenleiter, T. C., Romijn, J. A., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15736 · Cited by 363 · see citing works

Diurnal and Ultradian Dynamics of Serum Adiponectin in Healthy Men: Comparison with Leptin, Circulating Soluble Leptin Receptor, and Cortisol Patterns

Gavrila, A., Peng, C., Chan, J. L., Mietus, J. E., Goldberger, A. L., & Mantzoros, C. S. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021721 · Cited by 360 · see citing works

Aging in Rhesus Monkeys: Relevance to Human Health Interventions

Roth, G. S., Mattison, J. A., Ottinger, M. A., Chachich, M. E., Lane, M. A., & Ingram, D. K. (2004) · Science · doi:10.1126/science.1102541 · Cited by 354 · see citing works

Reciprocal Regulation of Brain and Muscle Arnt-Like Protein 1 and Peroxisome Proliferator-Activated Receptor α Defines a Novel Positive Feedback Loop in the Rodent Liver Circadian Clock

Canaple, L., Rambaud, J., Dkhissi‐Benyahya, O., Rayet, B., Tan, N. S., Michalik, L., Delaunay, F., Wahli, W., & Laudet, V. (2006) · Molecular Endocrinology · doi:10.1210/me.2006-0052 · Cited by 353 · see citing works

Sleep and circadian rhythms: key components in the regulation of energy metabolism

Laposky, A. D., Bass, J., Kohsaka, A., & Turek, F. W. (2008) · FEBS Letters · doi:10.1016/j.febslet.2007.06.079 · Cited by 351 · see citing works

Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus.

Baskin, D. G., Breininger, J. F., & Schwartz, M. W. (1999) · Diabetes · doi:10.2337/diabetes.48.4.828 · Cited by 351 · see citing works

Effect of shift work on body mass index: results of a study performed in 319 glucose-tolerant men working in a Southern Italian industry

Di Lorenzo, L., De Pergola, G., Zocchetti, C., L'Abbate, N., Basso, A., Pannacciulli, N., Cignarelli, M., Giorgino, R., & Soleo, L. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802419 · Cited by 346 · see citing works

Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue

Bamshad, M., Aoki, V. T., Adkison, M., Warren, W. S., & Bartness, T. J. (1998) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1998.275.1.r291 · Cited by 344 · see citing works

Minireview: Entrainment of the Suprachiasmatic Clockwork in Diurnal and Nocturnal Mammals

Challet, É. (2007) · Endocrinology · doi:10.1210/en.2007-0804 · Cited by 341 · see citing works

Living by the clock: The circadian pacemaker in older people

Hofman, M. A., & Swaab, D. F. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.07.001 · Cited by 335 · see citing works

Contrasting Effects of Ibotenate Lesions of the Paraventricular Nucleus and Subparaventricular Zone on Sleep–Wake Cycle and Temperature Regulation

Lu, J., Zhang, Y.-H., Chou, T. C., Gaus, S. E., Elmquist, J. K., Shiromani, P. J., & Saper, C. B. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-13-04864.2001 · Cited by 335 · see citing works

Local origins of some GABAergic projections to the paraventricular and supraoptic nuclei of the hypothalamus in the rat

Roland, B. L., & Sawchenko, P. E. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903320109 · Cited by 334 · see citing works

Selective parasympathetic innervation of subcutaneous and intra-abdominal fat — functional implications

Kreier, F., Fliers, E., Voshol, P. J., van Eden, C. G., Havekes, L. M., Kalsbeek, A., Heijningen, C. L. V., Sluiter, A. A., Mettenleiter, T. C., Romijn, J. A., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215736 · Cited by 331 · see citing works

Circadian Programs of Transcriptional Activation, Signaling, and Protein Turnover Revealed by Microarray Analysis of Mammalian Cells

Duffield, G. E., Best, J. D., Meurers, B. H., Bittner, A., Loros, J., & Dunlap, J. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00765-0 · Cited by 329 · see citing works

Obesity Without Sleep Apnea Is Associated With Daytime Sleepiness

Vgontzas, A. N., Bixler, E. O., Tan, T. L., Kantner, D., Martin, L. F., & Kales, A. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.12.1333 · Cited by 329 · see citing works

Circadian Clock Control by SUMOylation of BMAL1

Cardone, L., Hirayama, J., Giordano, F., Tamaru, T., Palvimo, J. J., & Sassone‐Corsi, P. (2005) · Science · doi:10.1126/science.1110689 · Cited by 329 · see citing works

Incidence of Diabetes in Middle-Aged Men Is Related to Sleep Disturbances

Nilsson, P. M., Rööst, M., Engström, G., Hedblad, B., & Berglund, G. (2004) · Diabetes Care · doi:10.2337/diacare.27.10.2464 · Cited by 322 · see citing works

Glucose Down-regulates Per1 and Per2mRNA Levels and Induces Circadian Gene Expression in Cultured Rat-1 Fibroblasts

Hirota, T., Okano, T., Kokame, K., Shirotani-Ikejima, H., Miyata, T., & Fukada, Y. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206233200 · Cited by 317 · see citing works

Effects of aging on central and peripheral mammalian clocks

Yamazaki, S., Straume, M., Tei, H., Sakaki, Y., Menaker, M., & Block, G. D. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.152318499 · Cited by 317 · see citing works

Metabolic disturbances in male workers with rotating three-shift work. Results of the WOLF study

Karlsson, B. H., Knutsson, A., Lindahl, B., & Alfredsson, L. S. (2003) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-003-0440-y · Cited by 316 · see citing works

Diurnal and Ultradian Rhythmicity of Plasma Leptin: Effects of Gender and Adiposity

Saad, M. F., Riad, M. G., Khan, A. M., Sharma, A., Michael, R., Jinagouda, S. D., Boyadjian, R., & Steil, G. M. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.2.4532 · Cited by 316 · see citing works

Rhythmic Messenger Ribonucleic Acid Expression of Clock Genes and Adipocytokines in Mouse Visceral Adipose Tissue

Ando, H., Yanagihara, H., Hayashi, Y., Obi, Y., Tsuruoka, S., Takamura, T., Kaneko, S., & Fujimura, A. (2005) · Endocrinology · doi:10.1210/en.2005-0771 · Cited by 312 · see citing works

Anticipation of 24-hr feeding schedules in rats with lesions of the suprachiasmatic nucleus

Stephan, F. K., Swann, J. M., & Sisk, C. L. (1979) · Behavioral and Neural Biology · doi:10.1016/s0163-1047(79)90415-1 · Cited by 310 · see citing works

The Suprachiasmatic Nucleus Generates the Diurnal Changes in Plasma Leptin Levels

Kalsbeek, A., Fliers, E., Romijn, J. A., la Fleur, S. E., Wortel, J., Bakker, O., Endert, E., & Buijs, R. M. (2001) · Endocrinology · doi:10.1210/endo.142.6.8197 · Cited by 305 · see citing works

Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation

Bodosi, B., Gardi, J., Hajdu, I., Szentirmai, É., Obál, F., & Krueger, J. M. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00294.2004 · Cited by 304 · see citing works

Circadian Disruption, Shift Work and the Risk of Cancer: A Summary of the Evidence and Studies in Seattle

Davis, S., & Mirick, D. K. (2006) · Cancer Causes &amp; Control · doi:10.1007/s10552-005-9010-9 · Cited by 302 · see citing works

CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor α (PPARα) in mice

Oishi, K., Shirai, H., & Ishida, N. (2005) · Biochemical Journal · doi:10.1042/bj20041150 · Cited by 296 · see citing works

Dietary factors, hormesis and health

Mattson, M. P. (2007) · Ageing Research Reviews · doi:10.1016/j.arr.2007.08.004 · Cited by 293 · see citing works

The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker

Mieda, M., Williams, S. C., Richardson, J. A., Tanaka, K., & Yanagisawa, M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604189103 · Cited by 290 · see citing works

The relationship between nutrition and circadian rhythms in mammals

Froy, O. (2007) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2007.03.001 · Cited by 286 · see citing works

Innervation of mammalian white adipose tissue: implications for the regulation of total body fat

Bartness, T. J., & Bamshad, M. (1998) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1998.275.5.r1399 · Cited by 285 · see citing works

Diet-induced Obesity Alters AMP Kinase Activity in Hypothalamus and Skeletal Muscle

Martin, T. L., Alquier, T., Asakura, K., Furukawa, N., Preitner, F., & Kahn, B. B. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m512831200 · Cited by 283 · see citing works

Effects of intermittent feeding upon body weight and lifespan in inbred mice: interaction of genotype and age

Goodrick, C. L., Ingram, D. K., Reynolds, M. A., Freeman, J. R., & Cider, N. (1990) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(90)90107-q · Cited by 279 · see citing works

The Significance of Circadian Organization for Longevity in the Golden Hamster

Hurd, M. W., & Ralph, M. R. (1998) · Journal of Biological Rhythms · doi:10.1177/074873098129000255 · Cited by 275 · see citing works

The Orphan Nuclear Receptor Rev-erbα Recruits the N-CoR/Histone Deacetylase 3 Corepressor to Regulate the Circadian Bmal1 Gene

Yin, L., & Lazar, M. A. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0057 · Cited by 274 · see citing works

Food restriction eliminates preneoplastic cells through apoptosis and antagonizes carcinogenesis in rat liver.

Grasl‐Kraupp, B., Bursch, W., Ruttkay-Nedecký, B., Wagner, A. E., Lauer, B., & Schulte‐Hermann, R. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.21.9995 · Cited by 268 · see citing works

High-fat meals reduce 24-h circulating leptin concentrations in women.

Havel, P. J., Townsend, R. R., Chaump, L., & Teff, K. L. (1999) · Diabetes · doi:10.2337/diabetes.48.2.334 · Cited by 268 · see citing works

Brain regulation of food intake and appetite: molecules and networks

Broberger, C. (2005) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2005.01553.x · Cited by 267 · see citing works

The role of mPer2 clock gene in glucocorticoid and feeding rhythms

Yang, S., Liu, A., Weidenhammer, A., Cooksey, R. C., McClain, D., Kim, M. K., Aguilera, G., Abel, E. D., & Chung, J. H. (2009) · Endocrinology · doi:10.1210/en.2008-0705 · Cited by 263 · see citing works

Sleep Loss Reduces Diurnal Rhythm Amplitude of Leptin in Healthy Men

Mullington, J. M., Chan, J. L., Van Dongen, H. P. A., Szuba, M. P., Samaras, J., Price, N. J., Meier‐Ewert, H. K., Dinges, D. F., & Mantzoros, C. S. (2003) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2003.01069.x · Cited by 261 · see citing works

Glucocorticoid signaling synchronizes the liver circadian transcriptome

Reddy, A. B., Maywood, E. S., Karp, N. A., King, V. M., Inoue, Y., Gonzalez, F. J., Lilley, K. S., Kyriacou, C. P., & Hastings, M. H. (2007) · Hepatology · doi:10.1002/hep.21571 · Cited by 261 · see citing works

Resetting Mechanism of Central and Peripheral Circadian Clocks in Mammals

Hirota, T., & Fukada, Y. (2004) · ZOOLOGICAL SCIENCE · doi:10.2108/zsj.21.359 · Cited by 260 · see citing works

The Biological Clock Nucleus: A Multiphasic Oscillator Network Regulated by Light

Quintero, J. E., Kuhlman, S. J., & McMahon, D. G. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-22-08070.2003 · Cited by 259 · see citing works

ENERGY INTAKE, MEAL FREQUENCY, AND HEALTH: A Neurobiological Perspective

Mattson, M. P. (2005) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.25.050304.092526 · Cited by 258 · see citing works

A Suprachiasmatic Nucleus Generated Rhythm In Basal Glucose Concentrations

Fleur, L., Kalsbeek, Wortel, & Buijs (1999) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1999.00373.x · Cited by 256 · see citing works

Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats

Mager, D. E., Wan, R., Brown, M., Cheng, A., Warȩski, P., Abernethy, D. R., & Mattson, M. P. (2006) · The FASEB Journal · doi:10.1096/fj.05-5263com · Cited by 251 · see citing works

The Orphan Nuclear Receptor Rev-Erbα Is a Peroxisome Proliferator-activated Receptor (PPAR) γ Target Gene and Promotes PPARγ-induced Adipocyte Differentiation

Fontaine, C., Dubois, G., Duguay, Y., Helledie, T., Vu‐Dac, N., Gervois, P. P., Soncin, F., Mandrup, S., Fruchart, J., Fruchart‐Najib, J., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304664200 · Cited by 248 · see citing works

Cardioprotection by Intermittent Fasting in Rats

Ahmet, I., Wan, R., Mattson, M. P., Lakatta, E. G., & Talan, M. I. (2005) · Circulation · doi:10.1161/circulationaha.105.563817 · Cited by 246 · see citing works

Activation of 5′-AMP-activated Kinase with Diabetes Drug Metformin Induces Casein Kinase Iɛ (CKIɛ)-dependent Degradation of Clock Protein mPer2

Um, J. H., Yang, S., Yamazaki, S., Kang, H., Viollet, B., Foretz, M., & Chung, J. H. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.c700070200 · Cited by 244 · see citing works

Vascular PPARγ Controls Circadian Variation in Blood Pressure and Heart Rate through Bmal1

Wang, N., Yang, G., Jia, Z., Zhang, H. E., Aoyagi, T., Soodvilai, S., Symons, J. D., Schnermann, J. B., Gonzalez, F. J., Litwin, S. E., et al. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.10.009 · Cited by 240 · see citing works

Independent circadian and sleep/wake regulation of adipokines and glucose in humans

Shea, S. A., Hilton, M. F., Orlova, C., Ayers, R. T., & Mantzoros, C. S. (2005) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2004-2232 · Cited by 240 · see citing works

A sense of time: how molecular clocks organize metabolism

Kohsaka, A., & Bass, J. T. (2006) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2006.11.005 · Cited by 233 · see citing works

Daily rhythms of food-anticipatory behavioral activity do not require the known circadian clock

Storch, K.-F., & Weitz, C. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902063106 · Cited by 222 · see citing works

Duration of shiftwork related to body mass index and waist to hip ratio

van Amelsvoort, L., Schouten, E., & Kok, F. J. (1999) · International Journal of Obesity · doi:10.1038/sj.ijo.0801028 · Cited by 221 · see citing works

The Dawn Phenomenon, an Early Morning Glucose Rise: Implications for Diabetic Intraday Blood Glucose Variation

Schmidt, M. I., Hadji-Georgopoulos, A., Rendell, M., Margolis, S., & Kowarski, A. (1981) · Diabetes Care · doi:10.2337/diacare.4.6.579 · Cited by 216 · see citing works

Chronic circadian desynchronization decreases the survival of animals with cardiomyopathic heart disease

Penev, P. D., Kolker, D. E., Zee, P. C., & Turek, F. W. (1998) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1998.275.6.h2334 · Cited by 216 · see citing works

Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity

Green, C. B., Douris, N., Kojima, S., Strayer, C. A., Fogerty, J., Lourim, D., Keller, S. R., & Besharse, J. C. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702448104 · Cited by 215 · see citing works

High-fat feeding alters the clock synchronization to light

Mendoza, J., Pévet, P., & Challet, E. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.159566 · Cited by 213 · see citing works

Circadian rhythms in the development of obesity: potential role for the circadian clock within the adipocyte

Bray, M. S., & Young, M. E. (2007) · Obesity Reviews · doi:10.1111/j.1467-789x.2006.00277.x · Cited by 213 · see citing works

The circadian clock within the heart: potential influence on myocardial gene expression, metabolism, and function

Young, M. E. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00582.2005 · Cited by 212 · see citing works

Feeding Cues Alter Clock Gene Oscillations and Photic Responses in the Suprachiasmatic Nuclei of Mice Exposed to a Light/Dark Cycle

Mendoza, J., Graff, C., Dardente, H., Pévet, P., & Challet, É. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4397-04.2005 · Cited by 211 · see citing works

Circadian and Light-Induced Transcription of Clock Gene Per1 Depends on Histone Acetylation and Deacetylation

Naruse, Y., Oh‐hashi, K., Iijima, N., Naruse, M., Yoshioka, H., & Tanaka, M. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.14.6278-6287.2004 · Cited by 209 · see citing works

Lack of Food Anticipation in Per2 Mutant Mice

Feillet, C. A., Ripperger, J. A., Magnone, M. C., Dulloo, A. G., Albrecht, U., & Challet, É. (2006) · Current Biology · doi:10.1016/j.cub.2006.08.053 · Cited by 208 · see citing works

Histone Acetyltransferase-dependent Chromatin Remodeling and the Vascular Clock

Curtis, A. M., Seo, S., Westgate, E. J., Rudic, R. D., Smyth, E. M., Chakravarti, D., FitzGerald, G. A., & McNamara, P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m311973200 · Cited by 208 · see citing works

Altered sleep regulation in leptin-deficient mice

Laposky, A. D., Shelton, J., Bass, J., Dugovic, C., Perrino, N., & Turek, F. W. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00304.2005 · Cited by 203 · see citing works

Induction of Rev-ErbA alpha, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation

Chawla, A., & Lazar, M. A. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85415-7 · Cited by 198 · see citing works

The effects of nocturnal life on endocrine circadian patterns in healthy adults

Qin, L.-Q., Li, J., Wang, Y., Wang, J., Xu, J.-Y., & Kaneko, T. (2003) · Life Sciences · doi:10.1016/s0024-3205(03)00628-3 · Cited by 192 · see citing works

The suprachiasmatic nucleus controls the daily variation of plasma glucose via the autonomic output to the liver: are the clock genes involved?

Cailotto, C., La Fleur, S. E., Van Heijningen, C., Wortel, J., Kalsbeek, A., Feenstra, M., Pévet, P., & Buijs, R. M. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04439.x · Cited by 191 · see citing works

Brain regulation of food intake and appetite: molecules and networks

Roberger, C. B. (2005) · Cited by 191 · see citing works

Organization of circadian functions: interaction with the body

Buijs, R. M., Scheer, F. A. J. L., Kreier, F., Yi, C., Bos, N. P. A., Goncharuk, V. D., & Kalsbeek, A. (2006) · Progress in brain research · doi:10.1016/s0079-6123(06)53020-1 · Cited by 189 · see citing works

Ventromedial Arcuate Nucleus Communicates Peripheral Metabolic Information to the Suprachiasmatic Nucleus

Yi, C., van der Vliet, J., Dai, J., Guangfu, Y., Li-qiang, R., & Buijs, R. M. (2005) · Endocrinology · doi:10.1210/en.2005-1051 · Cited by 184 · see citing works

Shift work and age as interactive predictors of body mass index among offshore workers

Parkes, K. R. (2002) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.648 · Cited by 182 · see citing works

Diurnal rhythm of phosphorylation of rat liver acetyl – CoA carboxylase by the AMP‐activated protein kinase, demonstrated using freeze‐clamping

DAVIES, S. P., Carling, D., Munday, M. R., & Hardie, D. G. (1992) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1992.tb16591.x · Cited by 179 · see citing works

Persistence of a behavioral food-anticipatory circadian rhythm following dorsomedial hypothalamic ablation in rats

Landry, G. J., Simon, M. M., Webb, I. C., & Mistlberger, R. E. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00874.2005 · Cited by 179 · see citing works

A role for cardiotrophin-like cytokine in the circadian control of mammalian locomotor activity

Kraves, S., & Weitz, C. J. (2006) · Nature Neuroscience · doi:10.1038/nn1633 · Cited by 177 · see citing works

Rhythmic, reciprocal ghrelin and leptin signaling: new insight in the development of obesity

Kalra, S. P., Bagnasco, M., Otukonyong, E. E., Dube, M. G., & Kalra, P. S. (2003) · Regulatory Peptides · doi:10.1016/s0167-0115(02)00305-1 · Cited by 177 · see citing works

Nocturnin, a Deadenylase in Xenopus laevis Retina

Baggs, J. E., & Green, C. B. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00014-9 · Cited by 175 · see citing works

The Polycomb Group Protein EZH2 Is Required for Mammalian Circadian Clock Function

Etchegaray, J., Yang, X., DeBruyne, J. P., Peters, A. H. F. M., Weaver, D. R., Jenuwein, T., & Reppert, S. M. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m603722200 · Cited by 174 · see citing works

Differential expression of mRNA for leptin receptor isoforms in the rat brain

Guan, X.-M., Hess, J. F., Yu, H., Hey, P. J., & van der Ploeg, L. H. T. (1997) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(97)00138-x · Cited by 173 · see citing works

Alcohol Consumption and the Body???s Biological Clock

Spanagel, R., Rosenwasser, A. M., Schumann, G., & Sarkar, D. K. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000175074.70807.fd · Cited by 172 · see citing works

The daily rhythm in plasma glucagon concentrations in the rat is modulated by the biological clock and by feeding behavior

Ruiter, M., La Fleur, S. E., van Heijningen, C., van der Vliet, J., Kalsbeek, A., & Buijs, R. M. (2003) · Diabetes · doi:10.2337/diabetes.52.7.1709 · Cited by 170 · see citing works

Bile acid signaling in metabolic disease and drug therapy

Li, T., & Chiang, J. Y. L. (2014) · Pharmacological Reviews · doi:10.1124/pr.113.008201 · Cited by 935 · see citing works

Timing of food intake predicts weight loss effectiveness

Garaulet, M., Gómez-Abellán, P., Alburquerque-Béjar, J. J., Lee, Y.-C., Ordovás, J. M., & Scheer, F. A. J. L. (2013) · International Journal of Obesity · doi:10.1038/ijo.2012.229 · Cited by 639 · see citing works

High Caloric intake at breakfast vs. dinner differentially influences weight loss of overweight and obese women

Jakubowicz, D., Barnea, M., Wainstein, J., & Froy, O. (2013) · Obesity · doi:10.1002/oby.20460 · Cited by 593 · see citing works

Circadian Clocks and Feeding Time Regulate the Oscillations and Levels of Hepatic Triglycerides

Adamovich, Y., Rousso-Noori, L., Zwighaft, Z., Neufeld-Cohen, A., Golik, M., Kraut-Cohen, J., Wang, M., Han, X., & Asher, G. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2013.12.016 · Cited by 410 · see citing works

The Circadian Syndrome: is the Metabolic Syndrome and much more!

Zimmet, P., Alberti, K. G. M. M., Stern, N., Bilu, C., El‐Osta, A., Einat, H., & Kronfeld‐Schor, N. (2019) · Journal of Internal Medicine · doi:10.1111/joim.12924 · Cited by 387 · see citing works

Timed high-fat diet resets circadian metabolism and prevents obesity

Sherman, H., Genzer, Y., Cohen, R., Chapnik, N., Madar, Z., & Froy, O. (2012) · The FASEB Journal · doi:10.1096/fj.12-208868 · Cited by 360 · see citing works

The neuroendocrinology of the microbiota-gut-brain axis: a behavioural perspective

Cussotto, S., Sandhu, K. V., Dinan, T. G., & Cryan, J. F. (2018) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2018.04.002 · Cited by 326 · see citing works

The nuclear receptor REV-ERBα is required for the daily balance of carbohydrate and lipid metabolism

Delezie, J., Dumont, S., Dardente, H., Oudart, H., Gréchez‐Cassiau, A., Klosen, P., Teboul, M., Delaunay, F., Pévet, P., & Challet, E. (2012) · The FASEB Journal · doi:10.1096/fj.12-208751 · Cited by 252 · see citing works

Circadian rhythms disrupted by light at night and mistimed food intake alter hormonal rhythms and metabolism

Meléndez-Fernández, O. H., Liu, J. A., & Nelson, R. J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043392 · Cited by 227 · see citing works

Human blood metabolite timetable indicates internal body time

Kasukawa, T., Sugimoto, M., Hida, A., Minami, Y., Mori, M., Honma, S., Honma, K.-I., Mishima, K., Soga, T., & Ueda, H. R. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1207768109 · Cited by 211 · see citing works

Dietary Factors and Fluctuating Levels of Melatonin

Peuhkuri, K., Sihvola, N., & Korpela, R. (2012) · Food &amp; Nutrition Research · doi:10.3402/fnr.v56i0.17252 · Cited by 194 · see citing works

Influences of Breakfast on Clock Gene Expression and Postprandial Glycemia in Healthy Individuals and Individuals With Diabetes: A Randomized Clinical Trial

Jakubowicz, D., Wainstein, J., Landau, Z., Raz, I., Ahren, B., Chapnik, N., Ganz, T., Menaged, M., Barnea, M., Bar-Dayan, Y., et al. (2017) · Diabetes Care · doi:10.2337/dc16-2753 · Cited by 178 · see citing works

Circadian Rhythms, Aging, and Life Span in Mammals

Froy, O. (2011) · Physiology · doi:10.1152/physiol.00012.2011 · Cited by 156 · see citing works

High-energy breakfast with low-energy dinner decreases overall daily hyperglycaemia in type 2 diabetic patients: a randomised clinical trial

Jakubowicz, D., Wainstein, J., Ahrén, B., Bar-Dayan, Y., Landau, Z., Rabinovitz, H. R., & Froy, O. (2015) · Diabetologia · doi:10.1007/s00125-015-3524-9 · Cited by 139 · see citing works

Thyroid Hormone Signaling and Homeostasis During Aging

Bowers, J., Terrien, J., Clerget-Froidevaux, M. S., Gothié, J. D., Rozing, M. P., Westendorp, R. G. J., van Heemst, D., & Demeneix, B. A. (2013) · Endocrine Reviews · doi:10.1210/er.2012-1056 · Cited by 117 · see citing works

Shift work as a risk factor for future type 2 diabetes: evidence, mechanisms, implications, and future research directions

Kivimäki, M., Batty, G. D., & Hublin, C. (2011) · PLoS Medicine · doi:10.1371/journal.pmed.1001138 · Cited by 110 · see citing works

A prospective study of weight gain associated with chronotype among college freshmen

Culnan, E., Kloss, J. D., & Grandner, M. (2013) · Chronobiology International · doi:10.3109/07420528.2013.782311 · Cited by 96 · see citing works

Assessment of maximal fat oxidation during exercise: A systematic review

Amaro‐Gahete, F. J., Sanchez‐Delgado, G., Jurado‐Fasoli, L., De‐la‐O, A., Castillo, M. J., Helge, J. W., & Ruiz, J. R. (2019) · Scandinavian Journal of Medicine &amp; Science in Sports · doi:10.1111/sms.13424 · Cited by 93 · see citing works

Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats

Reznick, J., Preston, E., Wilks, D. L., Beale, S. M., Turner, N., & Cooney, G. J. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.08.010 · Cited by 86 · see citing works

Combination of starvation interval and food volume determines the phase of liver circadian rhythm in <i>Per2::Luc</i> knock-in mice under two meals per day feeding

Hirao, A., Nagahama, H., Tsuboi, T., Hirao, M., Tahara, Y., & Shibata, S. (2010) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00330.2010 · Cited by 86 · see citing works

Effects of Caloric Intake Timing on Insulin Resistance and Hyperandrogenism in Lean Women with Polycystic Ovary Syndrome

Jakubowicz, D., Barnea, M., Wainstein, J., & Froy, O. (2013) · Clinical Science · doi:10.1042/cs20130071 · Cited by 81 · see citing works

Hypothalamic Orexin Prevents Hepatic Insulin Resistance via Daily Bidirectional Regulation of Autonomic Nervous System in Mice

Tsuneki, H., Tokai, E., Nakamura, Y., Takahashi, K., Fujita, M., Asaoka, T., Kon, K., Anzawa, Y., Wada, T., Takasaki, I., et al. (2015) · Diabetes · doi:10.2337/db14-0695 · Cited by 73 · see citing works

Chronic mild stress alters circadian expressions of molecular clock genes in the liver

Takahashi, K., Yamada, T., Tsukita, S., Kaneko, K., Shirai, Y., Munakata, Y., Ishigaki, Y., Imai, J., Uno, K., Hasegawa, Y., et al. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00388.2012 · Cited by 63 · see citing works

Polymorphism of CLOCK Gene rs 4580704 C&gt;G Is Associated with Susceptibility of Alzheimer’s Disease in a Chinese Population

Chen, H.-F., Huang, C.-Q., You, C., Wang, Z.-R., & Si-qing, H. (2013) · Archives of Medical Research · doi:10.1016/j.arcmed.2013.01.002 · Cited by 48 · see citing works

The Influence of Portion Size and Timing of Meals on Weight Balance and Obesity

Berg, C., & Forslund, H. B. (2015) · Current Obesity Reports · doi:10.1007/s13679-015-0138-y · Cited by 46 · see citing works

Time-of-day of energy intake: association with hypertension and blood pressure 10 years later in the 1946 British Birth Cohort

Almoosawi, S., Prynne, C. J., Hardy, R., & Stephen, A. M. (2013) · Journal of Hypertension · doi:10.1097/hjh.0b013e32835ecc06 · Cited by 46 · see citing works

Long‐term use of continuous subcutaneous hydrocortisone infusion therapy in patients with congenital adrenal hyperplasia

Mallappa, A., Nella, A. A., Sinaii, N., Rao, H., Gounden, V., Perritt, A. F., Kumar, P., Ling, A., Liu, C., Soldin, S. J., et al. (2018) · Clinical Endocrinology · doi:10.1111/cen.13813 · Cited by 45 · see citing works

Missing puzzle pieces of time-restricted-eating (TRE) as a long-term weight-loss strategy in overweight and obese people? A systematic review and meta-analysis of randomized controlled trials

Chen, J.-H., Lu, L. W., Ge, Q., Feng, D., Yu, J., Liu, B., Zhang, R., Zhang, X., Ouyang, C., & Chen, F. (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1974335 · Cited by 45 · see citing works

Sleep, circadian dysrhythmia, obesity and diabetes

Sridhar, G. R., & Sanjana, N. S. N. (2016) · World Journal of Diabetes · doi:10.4239/wjd.v7.i19.515 · Cited by 44 · see citing works

Inverse relationship of food and alcohol intake to sleep measures in obesity

Galli, G., Piaggi, P., Mattingly, M. S., de Jonge, L., Courville, A. B., Pinchera, A., Santini, F., Csako, G., Cizza, G., & for the Sleep Extension Study Group (2013) · Nutrition &amp; Diabetes · doi:10.1038/nutd.2012.33 · Cited by 36 · see citing works

Effects of consuming later evening meal<i>v</i>. earlier evening meal on weight loss during a weight loss diet: a randomised clinical trial

Madjd, A., Taylor, M. A., Delavari, A., Malekzadeh, R., Macdonald, I. A., & Farshchi, H. R. (2021) · British Journal of Nutrition · doi:10.1017/s0007114520004456 · Cited by 34 · see citing works

Physical activity, and not fat mass is a primary predictor of circadian parameters in young men

Tranel, H. R., Schroder, E. A., England, J., Black, W. S., Bush, H., Hughes, M. E., Esser, K. A., & Clasey, J. L. (2015) · Chronobiology International · doi:10.3109/07420528.2015.1043011 · Cited by 22 · see citing works

Restricted feeding-induced entrainment of activity rhythm and peripheral clock rhythm

Shibata, S., Hirao, A., & Tahara, Y. (2009) · Sleep and Biological Rhythms · doi:10.1111/j.1479-8425.2009.00417.x · Cited by 6 · see citing works

Circadian profile of Per gene mRNA expression in the suprachiasmatic nucleus, paraventricular nucleus, and pineal body of aged rats

Asai, M., Yoshinobu, Y., Kaneko, S., et al. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.10010.abs · Cited by 13 · see citing works

Circadian profile of Per gene mRNA expression in the suprachiasmatic nucleus, paraventricular nucleus, and pineal body of aged rats

Asai, M., Yoshinobu, Y., Kaneko, S., Mori, A., Nikaido, T., Moriya, T., Akiyama, M., & Shibata, S. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.10010 · Cited by 151 · see citing works

Editorial: Special Issue: circadian rhythms, clock genesand neuropsychiatry: interesting times

Coogan, A., & Thome, J. (2012) · Maynooth University ePrints and eTheses Archive (Maynooth University)

The Circadian Timing System: A Coordinator of Life Processes [Chronobiological Investigations]

Lévi, F. (2008) · IEEE Engineering in Medicine and Biology Magazine · doi:10.1109/memb.2007.907361 · Cited by 7 · see citing works