The DOI matches its Crossref record.
Activation of a Phytopathogenic Bacterial Effector Protein by a Eukaryotic Cyclophilin
Abstract
Innate immunity in higher plants invokes a sophisticated surveillance system capable of recognizing bacterial effector proteins. In Arabidopsis , resistance to infection by strains of Pseudomonas syringae expressing the effector AvrRpt2 requires the plant resistance protein RPS2. AvrRpt2 was identified as a putative cysteine protease that results in the elimination of the Arabidopsis protein RIN4. RIN4 cleavage serves as a signal to activate RPS2-mediated resistance. AvrRpt2 is delivered into the plant cell, where it is activated by a eukaryotic factor that we identify as cyclophilin. This activation of AvrRpt2 is necessary for protease activity. Active AvrRpt2 can then directly cleave RIN4.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Jones, J. D. G., & Dangl, J. L. (2006) · Nature · doi:10.1038/nature05286 · Cited by 13,177
Host-Microbe Interactions: Shaping the Evolution of the Plant Immune Response
Chisholm, S. T., Coaker, G., Day, B., & Staskawicz, B. J. (2006) · Cell · doi:10.1016/j.cell.2006.02.008 · Cited by 2,957
Self-citationPlant innate immunity: An updated insight into defense mechanism
Muthamilarasan, M., & Prasad, M. (2013) · Journal of Biosciences · doi:10.1007/s12038-013-9302-2 · Cited by 309
RIN4 Functions with Plasma Membrane H+-ATPases to Regulate Stomatal Apertures during Pathogen Attack
Liu, J., Elmore, J. M., Fuglsang, A. T., Palmgren, M. G., Staskawicz, B. J., & Coaker, G. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000139 · Cited by 275
Self-citation
Metadata
- Authors
- Coaker, G., Falick, A., & Staskawicz, B.
- Venue
- Science
- Published
- 2005-04-22
- Volume
- 308
- Issue
- 5721
- Pages
- 548-550
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2000912568
- Cited by
- 228
- References
- 0
- FWCI
- 22.56
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Activation of a Phytopathogenic Bacterial Effector Protein by a Eukaryotic Cyclophilin. https://app.cochat.ai/papers/10.1126/science.1108633
- The paper
- Coaker, G., Falick, A., & Staskawicz, B. (2005). Activation of a Phytopathogenic Bacterial Effector Protein by a Eukaryotic Cyclophilin. Science. https://doi.org/10.1126/science.1108633
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
