The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Polo-Like Kinase Cdc5 Controls the Local Activation of Rho1 to Promote Cytokinesis
Abstract
The links between the cell cycle machinery and the cytoskeletal proteins controlling cytokinesis are poorly understood. The small guanine nucleotide triphosphate (GTP)–binding protein RhoA stimulates type II myosin contractility and formin-dependent assembly of the cytokinetic actin contractile ring. We found that budding yeast Polo-like kinase Cdc5 controls the targeting and activation of Rho1 (RhoA) at the division site via Rho1 guanine nucleotide exchange factors. This role of Cdc5 (Polo-like kinase) in regulating Rho1 is likely to be relevant to cytokinesis and asymmetric cell division in other organisms.
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Cites
Global analysis of protein expression in yeast
Ghaemmaghami, S., Huh, W.-K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., & Weissman, J. S. (2003) · Nature · doi:10.1038/nature02046 · Cited by 3,750
Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells
Fujiwara, T., Bandi, M., Nitta, M., Ivanova, E. V., Bronson, R. T., & Pellman, D. (2005) · Nature · doi:10.1038/nature04217 · Cited by 1,067
Self-citationCytokinesis: Welcome to the Rho zone
Piekny, A., Werner, M., & Glotzer, M. (2005) · Trends in Cell Biology · doi:10.1016/j.tcb.2005.10.006 · Cited by 365
Cited by
Polo on the Rise—from Mitotic Entry to Cytokinesis with Plk1
Petronczki, M., Lénárt, P., & Peters, J.-M. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.04.014 · Cited by 485
Proteomic screen defines the Polo‐box domain interactome and identifies Rock2 as a Plk1 substrate
Lowery, D. M., Clauser, K. R., Hjerrild, M., Lim, D., Alexander, J., Kishi, K., Ong, S., Gammeltoft, S., Carr, S. A., & Yaffe, M. B. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601683 · Cited by 257
Self-citationRho GTPases: regulation of cell polarity and growth in yeasts
Perez, P., & Rincón, S. A. (2010) · Biochemical Journal · doi:10.1042/bj20091823 · Cited by 162
PTEN regulates PLK1 and controls chromosomal stability during cell division
Zhang, Z., Hou, S.-Q., He, J., Gu, T., Yin, Y., & Shen, W. H. (2016) · Cell Cycle · doi:10.1080/15384101.2016.1203493 · Cited by 46
Hoerndli, F. J., Pelech, S., Papassotiropoulos, A., & Götz, J. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05618.x · Cited by 34
Metadata
- Authors
- Yoshida, S., Kono, K., Lowery, D. M., Bartolini, S., Yaffe, M. B., Ohya, Y., & Pellman, D.
- Venue
- Science
- Published
- 2006-07-07
- Volume
- 313
- Issue
- 5783
- Pages
- 108-111
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2078631770
- Cited by
- 159
- References
- 3
- FWCI
- 5.87
- Type
- journal article
- Language
- en
- Open access
- closed
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