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Cited by 254

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Germ Cell Specification in Mice

Hayashi, Katsuhiko, de Sousa Lopes, Susana M. Chuva, Surani, M. Azim·2007·Science

Abstract

Specification of germ cells in mice occurs relatively late in embryonic development. It is initiated by signals that induce expression of Blimp1, a key regulator of the germ cell, in a few epiblast cells of early postimplantation embryos. Blimp1 represses the incipient somatic program in these cells and promotes progression toward the germ cell fate. Blimp1 may also have a role in the maintenance of early germ cell characteristics by ensuring their escape from the somatic fate as well as possible reversion to pluripotent stem cells.

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Crossref · 10.1126/science.1137545

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Metadata

Authors
Hayashi, K., de Sousa Lopes, S. M. C., & Surani, M. A.
Venue
Science
Published
2007-04-20
Volume
316
Issue
5823
Pages
394-396
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2057515238
Cited by
254
References
1
FWCI
8.62
Type
journal article
Language
en
Open access
closed

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