The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Postreplicative Formation of Cohesion Is Required for Repair and Induced by a Single DNA Break
Abstract
Sister-chromatid cohesion, established during replication by the protein complex cohesin, is essential for both chromosome segregation and double-strand break (DSB) repair. Normally, cohesion formation is strictly limited to the S phase of the cell cycle, but DSBs can trigger cohesion also after DNA replication has been completed. The function of this damage-induced cohesion remains unknown. In this investigation, we show that damage-induced cohesion is essential for repair in postreplicative cells in yeast. Furthermore, it is established genome-wide after induction of a single DSB, and it is controlled by the DNA damage response and cohesin-regulating factors. We thus define a cohesion establishment pathway that is independent of DNA duplication and acts together with cohesion formed during replication in sister chromatid–based DSB repair.
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Cites
Control of the DNA damage checkpoint by Chk1 and Rad53 protein kinases through distinct mechanisms
Sanchez, Y., Bachant, J., Wang, H., Hu, F., Liu, D., Tetzlaff, M., & Elledge, S. J. (1999) · Science · doi:10.1126/science.286.5442.1166 · Cited by 536
γH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
Stucki, M., & Jackson, S. P. (2006) · DNA Repair · doi:10.1016/j.dnarep.2006.01.012 · Cited by 412
Cited by
Regulation of DNA repair throughout the cell cycle
Branzei, D., & Foiani, M. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2351 · Cited by 1,228
Screen for DNA‐damage‐responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells
Tjeertes, J. V., Miller, K. M., & Jackson, S. P. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.119 · Cited by 347
Loop extrusion as a mechanism for formation of DNA damage repair foci
Arnould, C., Rocher, V., Finoux, A.-L., Clouaire, T., Li, K., Zhou, F., Caron, P., Mangeot, P. E., Ricci, E. P., Mourad, R., et al. (2021) · Nature · doi:10.1038/s41586-021-03193-z · Cited by 341
Tachibana-Konwalski, K., Godwin, J., van der Weyden, L., Champion, L., Kudo, N. R., Adams, D. J., & Nasmyth, K. (2010) · Genes & Development · doi:10.1101/gad.605910 · Cited by 265
WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation
Liu, N. Q., Maresca, M., van den Brand, T., Braccioli, L., Schijns, M. M. G. A., Teunissen, H., Bruneau, B. G., Nora, E. P., & de Wit, E. (2021) · Nature Genetics · doi:10.1038/s41588-020-00744-4 · Cited by 162
Metadata
- Authors
- Ström, L., Karlsson, C., Lindroos, H. B., Wedahl, S., Katou, Y., Shirahige, K., & Sjögren, C.
- Venue
- Science
- Published
- 2007-07-13
- Volume
- 317
- Issue
- 5835
- Pages
- 242-245
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1982367970
- Cited by
- 320
- References
- 2
- FWCI
- 12.21
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ström, L., Karlsson, C., Lindroos, H. B., Wedahl, S., Katou, Y., Shirahige, K., & Sjögren, C. (2007). Postreplicative Formation of Cohesion Is Required for Repair and Induced by a Single DNA Break. Science. https://doi.org/10.1126/science.1140649
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