The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Primary Immunodeficiencies: A Field in Its Infancy
Abstract
A paradigm shift is occurring in the field of primary immunodeficiencies, with revision of the definition of these conditions and a considerable expansion of their limits. Inborn errors of immunity were initially thought to be confined to a few rare, familial, monogenic, recessive traits impairing the development or function of one or several leukocyte subsets and resulting in multiple, recurrent, opportunistic, and fatal infections in infancy. A growing number of exceptions to each of these conventional qualifications have gradually accumulated. It now appears that most individuals suffer from at least one of a multitude of primary immunodeficiencies, the dissection of which is helping to improve human medicine while describing immunity in natura.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene
Duerr, R. H., Taylor, K. D., Brant, S. R., Rioux, J. D., Silverberg, M. S., Daly, M. J., Steinhart, A. H., Abraham, C., Regueiro, M., Griffiths, A., et al. (2006) · Science · doi:10.1126/science.1135245 · Cited by 3,039
ATM and related protein kinases: safeguarding genome integrity
Shiloh, Y. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1011 · Cited by 2,577
Genetic Dissection of Immunity to Mycobacteria: The Human Model
Casanova, J.-L., & Abel, L. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.081501.125851 · Cited by 991
Self-citationPyogenic Bacterial Infections in Humans with IRAK-4 Deficiency
Picard, C., Puel, A., Bonnet, M., Ku, C.-L., Bustamante, J., Yang, K., Soudais, C., Dupuis, S., Feinberg, J., Fieschi, C., et al. (2003) · Science · doi:10.1126/science.1081902 · Cited by 826
Self-citationHerpes Simplex Virus Encephalitis in Human UNC-93B Deficiency
Casrouge, A., Zhang, S.-Y., Eidenschenk, C., Jouanguy, E., Puel, A., Yang, K., Alcais, A., Picard, C., Mahfoufi, N., Nicolas, N., et al. (2006) · Science · doi:10.1126/science.1128346 · Cited by 725
Self-citationBuckley, R. H. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104614 · Cited by 532
The human model: a genetic dissection of immunity to infection in natural conditions
Casanova, J.-L., & Abel, L. (2004) · Nature Reviews Immunology · doi:10.1038/nri1264 · Cited by 277
Self-citationGrimbacher, B., Holland, S. M., & Puck, J. M. (2005) · Immunological Reviews · doi:10.1111/j.0105-2896.2005.00228.x · Cited by 262
Neutrophil elastase in cyclic and severe congenital neutropenia
Horwitz, M. S., Duan, Z., Korkmaz, B., Lee, H.-H., Mealiffe, M. E., & Salipante, S. J. (2006) · Blood · doi:10.1182/blood-2006-08-019166 · Cited by 249
Genetics of epidermodysplasia verruciformis: Insights into host defense against papillomaviruses
Orth, G. (2006) · Seminars in Immunology · doi:10.1016/j.smim.2006.07.008 · Cited by 249
Cited by
Immune adaptations that maintain homeostasis with the intestinal microbiota
Hooper, L. V., & Macpherson, A. J. (2010) · Nature Reviews Immunology · doi:10.1038/nri2710 · Cited by 1,454
Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity
Puel, A., Cypowyj, S., Bustamante, J., Wright, J. F., Liu, L., Lim, H. K., Migaud, M., Israel, L., Chrabieh, M., Audry, M., et al. (2011) · Science · doi:10.1126/science.1200439 · Cited by 1,056
Self-citationTLR3 Deficiency in Patients with Herpes Simplex Encephalitis
Zhang, S.-Y., Jouanguy, E., Ugolini, S., Smahi, A., Elain, G., Romero, P., Segal, D., Sancho-Shimizu, V., Lorenzo, L., Puel, A., et al. (2007) · Science · doi:10.1126/science.1139522 · Cited by 1,057
Self-citationMycobacterial Disease and Impaired IFN-γ Immunity in Humans with Inherited ISG15 Deficiency
Bogunovic, D., Byun, M., Durfee, L. A., Abhyankar, A., Sanal, O., Mansouri, D., Salem, S., Radovanovic, I., Grant, A. V., Adimi, P., et al. (2012) · Science · doi:10.1126/science.1224026 · Cited by 572
Self-citationBoisson, B., Laplantine, E., Prando, C., Giliani, S., Israelsson, E., Xu, Z., Abhyankar, A., Israël, L., Trevejo-Nunez, G., Bogunovic, D., et al. (2012) · Nature Immunology · doi:10.1038/ni.2457 · Cited by 474
Self-citation
Metadata
- Authors
- Casanova, J.-L., & Abel, L.
- Venue
- Science
- Published
- 2007-08-03
- Volume
- 317
- Issue
- 5838
- Pages
- 617-619
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2033732585
- Cited by
- 320
- References
- 40
- FWCI
- 9.87
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Primary Immunodeficiencies: A Field in Its Infancy. https://app.cochat.ai/papers/10.1126/science.1142963
- The paper
- Casanova, J.-L., & Abel, L. (2007). Primary Immunodeficiencies: A Field in Its Infancy. Science. https://doi.org/10.1126/science.1142963
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
