The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
The Eukaryotic Genome as an RNA Machine
Abstract
The past few years have revealed that the genomes of all studied eukaryotes are almost entirely transcribed, generating an enormous number of non–protein-coding RNAs (ncRNAs). In parallel, it is increasingly evident that many of these RNAs have regulatory functions. Here, we highlight recent advances that illustrate the diversity of ncRNA control of genome dynamics, cell biology, and developmental programming.
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Cites
The ENCODE Project Consortium (2007) · Nature · doi:10.1038/nature05874 · Cited by 5,223
Specific expression of long noncoding RNAs in the mouse brain
Mercer, T. R., Dinger, M. E., Sunkin, S. M., Mehler, M. F., & Mattick, J. S. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706729105 · Cited by 1,103
Self-citationThe Piwi-piRNA Pathway Provides an Adaptive Defense in the Transposon Arms Race
Aravin, A. A., Hannon, G. J., & Brennecke, J. (2007) · Science · doi:10.1126/science.1146484 · Cited by 1,096
An RNA gene expressed during cortical development evolved rapidly in humans
Pollard, K. S., Salama, S. R., Lambert, N., Lambot, M.-A., Coppens, S., Pedersen, J. S., Katzman, S., King, B., Onodera, C., Siepel, A., et al. (2006) · Nature · doi:10.1038/nature05113 · Cited by 1,005
Feng, J., Bi, C., Clark, B. S., Mady, R., Shah, P., & Kohtz, J. D. (2006) · Genes & Development · doi:10.1101/gad.1416106 · Cited by 712
Distinguishing protein-coding and noncoding genes in the human genome
Clamp, M., Fry, B., Kamal, M., Xie, X., Cuff, J., Lin, M. F., Kellis, M., Lindblad-Toh, K., & Lander, E. S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709013104 · Cited by 624
Drosophila PIWI associates with chromatin and interacts directly with HP1a
Brower-Toland, B., Findley, S. D., Jiang, L., Liu, L., Yin, H., Dus, M., Zhou, P., Elgin, S. C. R., & Lin, H. (2007) · Genes & Development · doi:10.1101/gad.1564307 · Cited by 350
Cited by
Cancer epigenetics: from mechanism to therapy
Dawson, M. A., & Kouzarides, T. (2012) · Cell · doi:10.1016/j.cell.2012.06.013 · Cited by 3,203
A conceptual framework for the developmental origins of health and disease
Gluckman, P. D., Hanson, M. A., & Buklijas, T. (2010) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174409990171 · Cited by 592
Nontemplated Nucleotide Additions Distinguish the Small RNA Composition in Cells from Exosomes
Koppers-Lalic, D., Hackenberg, M., Bijnsdorp, I. V., van Eijndhoven, M. A. J., Sadek, P., Sie, D., Zini, N., Middeldorp, J. M., Ylstra, B., de Menezes, R. X., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.08.027 · Cited by 560
The epigenetics of aging and neurodegeneration
Lardenoije, R., Iatrou, A., Kenis, G., Kompotis, K., Steinbusch, H. W. M., Mastroeni, D., Coleman, P., Lemere, C. A., Hof, P. R., van den Hove, D. L. A., et al. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.05.002 · Cited by 381
Functional Analysis of the Chromosome 9p21.3 Coronary Artery Disease Risk Locus
Jarinova, O., Stewart, A. F. R., Roberts, R., Wells, G., Lau, P., Naing, T., Buerki, C., McLean, B. W., Cook, R. C., Parker, J. S., et al. (2009) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.109.189522 · Cited by 384
Metadata
- Authors
- Amaral, P. P., Dinger, M. E., Mercer, T. R., & Mattick, J. S.
- Venue
- Science
- Published
- 2008-03-28
- Volume
- 319
- Issue
- 5871
- Pages
- 1787-1789
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1977937947
- Cited by
- 619
- References
- 7
- FWCI
- 20.92
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Eukaryotic Genome as an RNA Machine. https://app.cochat.ai/papers/10.1126/science.1155472
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- Amaral, P. P., Dinger, M. E., Mercer, T. R., & Mattick, J. S. (2008). The Eukaryotic Genome as an RNA Machine. Science. https://doi.org/10.1126/science.1155472
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
