High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

Yu, Haiyuan, Braun, Pascal, Yıldırım, Muhammed A., Lemmens, Irma, Venkatesan, Kavitha, Sahalie, Julie, Hirozane-Kishikawa, Tomoko, Gebreab, Fana, Li, Na, Simonis, Nicolas, Hao, Tong, Rual, Jean-François, Dricot, Amélie, Vazquez, Alexei, Murray, Ryan R., Simon, Christophe, Tardivo, Leah, Tam, Stanley, Svrzikapa, Nenad, Fan, Changyu, de Smet, Anne-Sophie, Motyl, Adriana, Hudson, Michael E., Park, Juyong, Xin, Xiaofeng, Cusick, Michael E., Moore, Troy, Boone, Charlie, Snyder, Michael, Roth, Frederick P., Barabási, Albert-László, Tavernier, Jan, Hill, David E., Vidal, Marc·2008·Science
DOI 10.1126/science.1158684

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  19. M-Finder: Uncovering functionally associated proteins from interactome data integrated with GO annotations
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    Joseph Ivanic, Xueping Yu, Anders Wallqvist, Jaques Reifman A · 2009 · PLoS ONE
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  60. Targeting ligand-gated ion channels in neurology and psychiatry: is pharmacological promiscuity an obstacle or an opportunity?
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  66. Simple Topological Features Reflect Dynamics and Modularity in Protein Interaction Networks
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  80. From evidence to inference: Probing the evolution of protein interaction networks
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  81. Regulatory patterns in molecular interaction networks
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  82. Interactive learning: Lessons from two hybrids over two decades
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  83. A scalable double-barcode sequencing platform for characterization of dynamic protein-protein interactions
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  84. FOCS: Fast Overlapped Community Search
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