The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.
The Tail of Integrins, Talin, and Kindlins
Abstract
Tales of Talin, Kindlin, and Integrin: The integrins are receptors on the surface of animal cells that mediate attachment to the extracellular matrix. Integrins also act as signaling molecules, activating signaling pathways when they bind to their ligands in the matrix. Furthermore, integrins can communicate signals from the inside to the outside of the cell when signals within the cell alter the affinity of integrins for their extracellular ligands. Moser et al. (p. 895 ) review recent advances in understanding the roles of the proteins talin and kindlin in such bidirectional signaling and how they influence the function of integrins in health and disease.
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Hynes (2002) · doi:10.1016/s0092-8674(02)00971-6 · Cited by 8,606
Structural Basis of Integrin Regulation and Signaling
Luo, B.-H., Carman, C. V., & Springer, T. A. (2007) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141618 · Cited by 1,660
Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation
Tadokoro, S., Shattil, S. J., Eto, K., Tai, V., Liddington, R. C., de Pereda, J. M., Ginsberg, M. H., & Calderwood, D. A. (2003) · Science · doi:10.1126/science.1086652 · Cited by 1,209
Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage
Horwitz, A., Duggan, K., Buck, C., Beckerle, M. C., & Burridge, K. (1986) · Nature · doi:10.1038/320531a0 · Cited by 1,192
Genetic and cell biological analysis of integrin outside-in signaling
Legate, K. R., Wickström, S. A., & Fässler, R. (2009) · Genes & Development · doi:10.1101/gad.1758709 · Cited by 802
Self-citationBidirectional Transmembrane Signaling by Cytoplasmic Domain Separation in Integrins
Kim, M., Carman, C. V., & Springer, T. A. (2003) · Science · doi:10.1126/science.1084174 · Cited by 786
Calderwood, D. A., Zent, R., Grant, R., Rees, D. J. G., Hynes, R. O., & Ginsberg, M. H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.40.28071 · Cited by 720
Self-citationKindlin-3 is essential for integrin activation and platelet aggregation
Moser, M., Nieswandt, B., Ussar, S., Pozgajova, M., & Fässler, R. (2008) · Nature Medicine · doi:10.1038/nm1722 · Cited by 700
Self-citationKrüger, M., Moser, M., Ussar, S., Thievessen, I., Luber, C. A., Forner, F., Schmidt, S., Zanivan, S., Fässler, R., & Mann, M. (2008) · Cell · doi:10.1016/j.cell.2008.05.033 · Cited by 680
Self-citationStructural Basis of Integrin Activation by Talin
Wegener, K. L., Partridge, A. W., Han, J., Pickford, A. R., Liddington, R. C., Ginsberg, M. H., & Campbell, I. D. (2007) · Cell · doi:10.1016/j.cell.2006.10.048 · Cited by 676
Cited by
The final steps of integrin activation: the end game
Shattil, S. J., Kim, C., & Ginsberg, M. H. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2871 · Cited by 1,086
How leukocytes cross the vascular endothelium
Vestweber, D. (2015) · Nature Reviews Immunology · doi:10.1038/nri3908 · Cited by 858
Phagocytosis: Receptors, signal integration, and the cytoskeleton
Freeman, S. A., & Grinstein, S. (2014) · Immunological Reviews · doi:10.1111/imr.12212 · Cited by 548
Integrins: masters and slaves of endocytic transport
Caswell, P. T., Vadrevu, S., & Norman, J. C. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2799 · Cited by 460
Exploring the Role of RGD-Recognizing Integrins in Cancer
Nieberler, M., Reuning, U., Reichart, F., Notni, J., Wester, H.-J., Schwaiger, M., Weinmüller, M., Räder, A., Steiger, K., & Kessler, H. (2017) · Cancers · doi:10.3390/cancers9090116 · Cited by 429
Metadata
- Authors
- Moser, M., Legate, K. R., Zent, R., & Fässler, R.
- Venue
- Science
- Published
- 2009-05-15
- Volume
- 324
- Issue
- 5929
- Pages
- 895-899
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2058624823
- Cited by
- 760
- References
- 77
- FWCI
- 53.48
- Type
- journal article
- Language
- en
- Open access
- closed
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- Moser, M., Legate, K. R., Zent, R., & Fässler, R. (2009). The Tail of Integrins, Talin, and Kindlins. Science. https://doi.org/10.1126/science.1163865
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
