Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α
Zhao, Shimin, Lin, Yan, Xu, Wei, Jiang, Wenqing, Zha, Zhengyu, Wang, Pu, Yu, Wei, Li, Zhiqiang, Gong, Lingling, Peng, Yingjie, Ding, Jianping, Lei, Qunying, Guan, Kun-Liang, Xiong, Yue·2009·Science
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- Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric gliomaAditya Raghunathan, Adriana Olar, Hannes S. Vogel, John R. Parker, Susan C. Coventry, Robert Debski, Constance T. Albarracin, Kenneth Aldape, Daniel P. Cahill, Suzanne Zein-Eldin Powell et al. · 2012 · Annals of Diagnostic Pathology
- Emerging Approaches for Targeting Metabolic Vulnerabilities in Malignant GliomaPeter M. Clark, Wilson X. Mai, Timothy Francis Cloughesy, David A. Nathanson · 2016 · Current Neurology and Neuroscience Reports
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- IDH1 mutation, a genetic alteration associated with adult gliomatosis cerebriDeepti Narasimhaiah, Catherine Miquel, Elisabeth Verhamme, Paul Desclée, Guy Cosnard, Catherine Godfraind · 2011 · Neuropathology
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- Metabolism and cancer: an up-to-date review of a mutual connection.Alexios‐Fotios A. Mentis, Evangelia G. Kararizou · 2010 · PubMed
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- The connection between tricarboxylic acid cycle enzyme mutations and pseudohypoxic signaling in pheochromocytoma and paragangliomaWang, Yuxiong, Liu, Bin, Li, Faping, Zhang, Yanghe, Gao, Xin, Wang, Yishu, Zhou, Honglan · 2023 · Frontiers in Endocrinology
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- Molecular mechanisms of retinal ischemiaSeth D. Fortmann, Maria B. Grant · 2018 · Current Opinion in Physiology
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