The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Partitioning of Histone H3-H4 Tetramers During DNA Replication–Dependent Chromatin Assembly
Abstract
Histone Inheritance: Chromatin, the packaging material for eukaryotic genomes, is a potential repository for epigenetic information. The core structure of chromatin is the nucleosome, which consists of an octamer of histone proteins, two dimers each of histones H2A and H2B, and histones 3 and 4. Histones 3 and 4, in particular, carry a series of covalent modifications presumed to be passed on through cell division. Using mass spectrometry of tagged and isotope labeled histones, Xu et al. (p. 94 ; see the Perspective by Ray-Gallet and Almouzni ) followed the inheritance of the histones themselves through mitosis. The H2A-H2B dimers were inherited randomly through cell division, correlating with their lack of major covalent marks. In comparison, replication-deposited H3.1-H4 dimers did not separate through cell division, implying that H3 and H4 histone modifications might be maintained by copying from neighboring preexisting histones. Intriguingly, up to one-quarter of the nonreplication-deposited H3.3-H4 dimers, which mark active chromatin, did split during cell division.
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Citations
Cites
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The Histone Variant H3.3 Marks Active Chromatin by Replication-Independent Nucleosome Assembly
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Cited by
Histone methylation: a dynamic mark in health, disease and inheritance
Greer, E. L., & Shi, Y. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3173 · Cited by 2,241
Regulation of nucleosome dynamics by histone modifications
Zentner, G. E., & Henikoff, S. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2470 · Cited by 923
Deans, C., & Maggert, K. A. (2015) · Genetics · doi:10.1534/genetics.114.173492 · Cited by 554
Understanding nucleosome dynamics and their links to gene expression and DNA replication
Lai, W. K. M., & Pugh, B. F. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.47 · Cited by 495
Effector T cell plasticity: flexibility in the face of changing circumstances
Murphy, K. M., & Stockinger, B. (2010) · Nature Immunology · doi:10.1038/ni.1899 · Cited by 482
Metadata
- Authors
- Xu, M., Long, C., Chen, X., Huang, C., Chen, S., & Zhu, B.
- Venue
- Science
- Published
- 2010-04-02
- Volume
- 328
- Issue
- 5974
- Pages
- 94-98
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2084396631
- Cited by
- 351
- References
- 27
- FWCI
- 12.52
- Type
- journal article
- Language
- en
- Open access
- closed
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