The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production
Open accessAbstract
Platelet Microparticles Drive Inflammatory Arthritis: Platelets are best known for their critical role in blood clot formation during wound repair, but an appreciation for their role in inflammatory processes is growing. Platelet-derived cellular microparticles (MPs) are small membrane vesicles released from platelets in response to cell activation that can transport biomolecules throughout the body that have also been implicated in inflammatory processes. Boilard et al. (p. 580 ; see the Perspective by Zimmerman and Weyrich ) have now found that platelet-derived MPs probably contribute to the inflammatory processes underlying rheumatoid arthritis, an autoimmune disease. The majority of MPs in synovial fluid from patients with various types of inflammatory arthritis were platelet-derived and, importantly, platelet-derived MPs were lacking in synovial fluid from osteoarthritis patients. Furthermore, platelet depletion abrogated disease development in a mouse model of inflammatory arthritis.
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Platelet Activation and Atherothrombosis
Davì, G., & Patrono, C. (2007) · New England Journal of Medicine · doi:10.1056/nejmra071014 · Cited by 2,135
Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part I
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The Nature and Significance of Platelet Products in Human Plasma
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Self-citationPlatelet-collagen interaction: is GPVI the central receptor?
Nieswandt, B., & Watson, S. P. (2003) · Blood · doi:10.1182/blood-2002-12-3882 · Cited by 1,150
Activated platelets mediate inflammatory signaling by regulated interleukin 1β synthesis
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Self-citationPlatelets mediate cytotoxic T lymphocyte–induced liver damage
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Yáñez‐Mó, M., Siljander, P. R. ‐., Andreu, Z., Bedina Zavec, A., Borràs, F. E., Buzas, E. I., Buzas, K., Casal, E., Cappello, F., Carvalho, J., et al. (2015) · Journal of Extracellular Vesicles · doi:10.3402/jev.v4.27066 · Cited by 5,926
Neutrophil recruitment and function in health and inflammation
Kolaczkowska, E., & Kubes, P. (2013) · Nature Reviews Immunology · doi:10.1038/nri3399 · Cited by 5,472
Visscher, P. M., Brown, M. A., McCarthy, M. I., & Yang, J. (2012) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2011.11.029 · Cited by 2,425
Boudreau, L. H., Duchez, A.-C., Cloutier, N., Soulet, D., Martin, N., Bollinger, J., Paré, A., Rousseau, M., Naika, G. S., Lévesque, T., et al. (2014) · Blood · doi:10.1182/blood-2014-05-573543 · Cited by 703
Self-citationChromatin marks identify critical cell types for fine mapping complex trait variants
Trynka, G., Sandor, C., Han, B., Xu, H., Stranger, B. E., Liu, X. S., & Raychaudhuri, S. (2013) · Nature Genetics · doi:10.1038/ng.2504 · Cited by 580
Metadata
- Authors
- Boilard, E., Nigrovic, P. A., Larabee, K., Watts, G. F. M., Coblyn, J. S., Weinblatt, M. E., Massarotti, E. M., Remold-O’Donnell, E., Farndale, R. W., Ware, J., & Lee, D. M.
- Venue
- Science
- Published
- 2010-01-29
- Volume
- 327
- Issue
- 5965
- Pages
- 580-583
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2150752051
- Cited by
- 1,085
- References
- 25
- FWCI
- 46.87
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production. https://app.cochat.ai/papers/10.1126/science.1181928
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- Boilard, E., Nigrovic, P. A., Larabee, K., Watts, G. F. M., Coblyn, J. S., Weinblatt, M. E., Massarotti, E. M., Remold-O’Donnell, E., Farndale, R. W., Ware, J., & Lee, D. M. (2010). Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production. Science. https://doi.org/10.1126/science.1181928
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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