The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Tuberculosis: What We Don’t Know Can, and Does, Hurt Us
Open accessAbstract
Mycobacterium tuberculosis has a penetrance of its host population that would be the envy of most human pathogens. About one-third of the human population would have a positive skin test for the infection and is thus thought to harbor the bacterium. Globally, 22 “high-burden” countries account for more than 80% of the active tuberculosis cases in the world, which shows the inequitable distribution of the disease. There is no effective vaccine against infection, and current drug therapies are fraught with problems, predominantly because of the protracted nature of the treatment and the increasing occurrence of drug resistance. Here we focus on the biology of the host-pathogen interaction and discuss new and evolving strategies for intervention.
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Cites
Mycobacterial persistence requires the utilization of host cholesterol
Pandey, A. K., & Sassetti, C. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711159105 · Cited by 1,064
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Tuberculosis Vaccines and Prevention of Infection
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Corleis, B., Korbel, D., Wilson, R., Bylund, J., Chee, R., & Schaible, U. E. (2012) · Cellular Microbiology · doi:10.1111/j.1462-5822.2012.01783.x · Cited by 150
Metadata
- Authors
- Russell, D. G., Barry, C. E., & Flynn, J. L.
- Venue
- Science
- Published
- 2010-05-14
- Volume
- 328
- Issue
- 5980
- Pages
- 852-856
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1981824586
- Cited by
- 489
- References
- 1
- FWCI
- 35.55
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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