RIGorous Detection: Exposing Virus Through RNA Sensing

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The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-I

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5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

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Cytosolic Viral Sensor RIG-I Is a 5'-Triphosphate–Dependent Translocase on Double-Stranded RNA

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Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

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STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

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MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

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The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop

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Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

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The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus

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Ubiquitin-Induced Oligomerization of the RNA Sensors RIG-I and MDA5 Activates Antiviral Innate Immune Response

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Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

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Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5

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The role of ubiquitylation in immune defence and pathogen evasion

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Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

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The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy

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Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection

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Induction of Siglec-G by RNA Viruses Inhibits the Innate Immune Response by Promoting RIG-I Degradation

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NLRX1 Negatively Regulates TLR-Induced NF-κB Signaling by Targeting TRAF6 and IKK

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Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

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Constitutive aryl hydrocarbon receptor signaling constrains type I interferon-mediated antiviral innate defense

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Expanding role of ubiquitination in NF-κB signaling

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Intratumoral Delivery of Immunotherapy—Act Locally, Think Globally

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ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses

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A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity

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Encephalomyocarditis Virus Viroporin 2B Activates NLRP3 Inflammasome

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Innate Sensing of HIV-Infected Cells

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Toll-like receptor 3, RIG-I-like receptors and the NLRP3 inflammasome: Key modulators of innate immune responses to double-stranded RNA viruses

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Post‐translational regulation of antiviral innate signaling

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RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP

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Inhibition of Dengue and Chikungunya Virus Infections by RIG-I-Mediated Type I Interferon-Independent Stimulation of the Innate Antiviral Response

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Molecular Mechanism of Signal Perception and Integration by the Innate Immune Sensor Retinoic Acid-inducible Gene-I (RIG-I)

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Comparative Structural Analysis of Human DEAD-Box RNA Helicases

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Rapid electrochemical detection of single influenza viruses tagged with silver nanoparticles

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Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity

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RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradation

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TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus

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Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome

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Efficient RNA virus control in Drosophila requires the RNA methyltransferase Dnmt2

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Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism

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Cytosolic surveillance and antiviral immunity

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Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists

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Autophagy regulates MAVS signaling activation in a phosphorylation-dependent manner in microglia

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Curating the innate immunity interactome

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DDIT3 Targets Innate Immunity via the DDIT3-OTUD1-MAVS Pathway To Promote Bovine Viral Diarrhea Virus Replication

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Advances in Oral Subunit Vaccine Design

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Both TLR2 and TRIF Contribute to Interferon-β Production during Listeria Infection

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Two Conserved Amino Acids within the NSs of Severe Fever with Thrombocytopenia Syndrome Phlebovirus Are Essential for Anti-interferon Activity

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Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3

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Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis

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A review on the DNA methyltransferase family of insects: Aspect and prospects

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Autophagy in Viral Infection and Pathogenesis

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MRG15 aggravates non-alcoholic steatohepatitis progression by regulating the mitochondrial proteolytic degradation of TUFM

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RIG-I Mediates an Antiviral Response to Crimean-Congo Hemorrhagic Fever Virus

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Astronomical context of Solar System formation from molybdenum isotopes in meteorite inclusions

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Functional Characterizations of RIG-I to GCRV and Viral/Bacterial PAMPs in Grass Carp Ctenopharyngodon idella

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Autocrine Interferon Priming in Macrophages but Not Dendritic Cells Results in Enhanced Cytokine and Chemokine Production after Coronavirus Infection

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Activation of TLR3 Induces Osteogenic Responses in Human Aortic Valve Interstitial Cells through the NF-κB and ERK1/2 Pathways

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Identification of the RNA Pseudoknot within the 3′ End of the Porcine Reproductive and Respiratory Syndrome Virus Genome as a Pathogen-Associated Molecular Pattern To Activate Antiviral Signaling via RIG-I and Toll-Like Receptor 3

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Deciphering the differential response of two human fibroblast cell lines following Chikungunya virus infection

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The kinase CK1ɛ controls the antiviral immune response by phosphorylating the signaling adaptor TRAF3

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Structural Insights into the Evolution of the Adaptive Immune System

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IRF3 Negatively Regulates Toll-Like Receptor-Mediated NF-κB Signaling by Targeting TRIF for Degradation in Teleost Fish

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Ubiquitin E3 ligase MID1 inhibits the innate immune response by ubiquitinating IRF3

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CD97 negatively regulates the innate immune response against RNA viruses by promoting RNF125-mediated RIG-I degradation

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So similar, yet so different: Selective translation of capped and polyadenylated viral mRNAs in the influenza virus infected cell

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Correction: Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity

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Cytoplasmic recognition of RNA☆

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An evolving arsenal: viral RNA detection by RIG-I-like receptors

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