The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Genome-Wide Kinetics of Nucleosome Turnover Determined by Metabolic Labeling of Histones
Open accessAbstract
Everything Changes: Nucleosomes package DNA, and their assembly and disassembly regulate access to the genome. The ability to follow these changes is limited to steady-state methods in higher eukaryotes, although direct kinetic analyses are available in yeast. To address this deficiency, Deal et al. (p. 1161 ) developed a general method for following the genome-wide dynamics of nucleosome assembly and disassembly. High levels of nucleosome turnover were observed across gene bodies and at the sites of epigenetic regulatory elements in fruit fly tissue culture cells. Nucleosomes were replaced multiple times during each 20-hour cell cycle, suggesting that histone modifications themselves are unlikely to transmit epigenetic information. Furthermore, analysis of replication origins indicates that they are determined by chromatin dynamics and not by sequence features.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Dieterich, D. C., Link, A. J., Graumann, J., Tirrell, D. A., & Schuman, E. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601637103 · Cited by 874
Dynamics of Replication-Independent Histone Turnover in Budding Yeast
Dion, M. F., Kaplan, T., Kim, M., Buratowski, S., Friedman, N., & Rando, O. J. (2007) · Science · doi:10.1126/science.1134053 · Cited by 556
Rufiange, A., Jacques, P.-É., Bhat, W., Robert, F., & Nourani, A. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.07.011 · Cited by 313
Cited by
Chromatin accessibility and the regulatory epigenome
Klemm, S. L., Shipony, Z., & Greenleaf, W. J. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-018-0089-8 · Cited by 1,793
Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
Black, J. C., Van Rechem, C., & Whetstine, J. R. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.11.006 · Cited by 1,308
Charting histone modifications and the functional organization of mammalian genomes
Zhou, V. W., Goren, A., & Bernstein, B. E. (2011) · Nature Reviews Genetics · doi:10.1038/nrg2905 · Cited by 1,147
Regulation of nucleosome dynamics by histone modifications
Zentner, G. E., & Henikoff, S. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2470 · Cited by 923
Self-citationComprehensive analysis of the chromatin landscape in Drosophila melanogaster
Kharchenko, P. V., Alekseyenko, A. A., Schwartz, Y. B., Minoda, A., Riddle, N. C., Ernst, J., Sabo, P. J., Larschan, E., Gorchakov, A. A., Gu, T., et al. (2011) · Nature · doi:10.1038/nature09725 · Cited by 873
Metadata
- Authors
- Deal, R. B., Henikoff, J. G., & Henikoff, S.
- Venue
- Science
- Published
- 2010-05-28
- Volume
- 328
- Issue
- 5982
- Pages
- 1161-1164
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2031156443
- Cited by
- 471
- References
- 3
- FWCI
- 22.92
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Genome-Wide Kinetics of Nucleosome Turnover Determined by Metabolic Labeling of Histones. https://app.cochat.ai/papers/10.1126/science.1186777
- The paper
- Deal, R. B., Henikoff, J. G., & Henikoff, S. (2010). Genome-Wide Kinetics of Nucleosome Turnover Determined by Metabolic Labeling of Histones. Science. https://doi.org/10.1126/science.1186777
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
