The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Astrocytes Control Breathing Through pH-Dependent Release of ATP
Open accessAbstract
Astrocytes, ATP, Brainstem, and Breathing: Astrocytes (or glial cells), previously assumed to be passive players in brain physiology, may play a functional role in a number of complex behaviors. The central chemosensory control of breathing involves highly specialized neuronal populations in the brainstem, but what about astrocytes? Gourine et al. (p. 571 , published online 15 July) now present evidence that glial cells may help to control breathing. A number of techniques were used to reveal glial calcium rises in vitro that elicit a depolarization of neurons in the primary locus for central respiratory chemosensitivity. The depolarization in these neurons is evoked by vesicular release of ATP in neighboring astrocytes in response to the fall in extracellular pH. Thus, brainstem astrocytes have the ability to sense changes in blood and brain CO 2 , and pH directly, and may control the activity of the respiratory neuronal networks to regulate breathing.
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Long-term potentiation depends on release of d-serine from astrocytes
Henneberger, C., Papouin, T., Oliet, S. H. R., & Rusakov, D. A. (2010) · Nature · doi:10.1038/nature08673 · Cited by 1,389
Astrocytic Purinergic Signaling Coordinates Synaptic Networks
Pascual, O., Casper, K. B., Kubera, C., Zhang, J., Revilla-Sanchez, R., Sul, J.-Y., Takano, H., Moss, S. J., McCarthy, K., & Haydon, P. G. (2005) · Science · doi:10.1126/science.1116916 · Cited by 1,280
Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo
Wang, X., Lou, N., Xu, Q., Tian, G.-F., Peng, W. G., Han, X., Kang, J., Takano, T., & Nedergaard, M. (2006) · Nature Neuroscience · doi:10.1038/nn1703 · Cited by 685
Cited by
Optogenetics in neural systems
Yizhar, O., Fenno, L. E., Davidson, T. J., Mogri, M., & Deisseroth, K. (2011) · Neuron · doi:10.1016/j.neuron.2011.06.004 · Cited by 1,881
Self-citationThe development and application of optogenetics
Fenno, L., Yizhar, O., & Deisseroth, K. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113817 · Cited by 1,822
Self-citationVerkhratsky, A., & Nedergaard, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00042.2016 · Cited by 1,678
Gliotransmitters Travel in Time and Space
Araque, A., Carmignoto, G., Haydon, P. G., Oliet, S. H. R., Robitaille, R., & Volterra, A. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.007 · Cited by 1,308
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Khakh, B. S., & Sofroniew, M. V. (2015) · Nature Neuroscience · doi:10.1038/nn.4043 · Cited by 1,239
Metadata
- Authors
- Gourine, A. V., Kasymov, V., Marina, N., Tang, F., Figueiredo, M. F., Lane, S., Teschemacher, A. G., Spyer, K. M., Deisseroth, K., & Kasparov, S.
- Venue
- Science
- Published
- 2010-07-30
- Volume
- 329
- Issue
- 5991
- Pages
- 571-575
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2032154466
- Cited by
- 872
- References
- 3
- FWCI
- 30.08
- Type
- journal article
- Language
- en
- Open access
- green
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- Gourine, A. V., Kasymov, V., Marina, N., Tang, F., Figueiredo, M. F., Lane, S., Teschemacher, A. G., Spyer, K. M., Deisseroth, K., & Kasparov, S. (2010). Astrocytes Control Breathing Through pH-Dependent Release of ATP. Science. https://doi.org/10.1126/science.1190721
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