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Cited by 422

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Crystal Structure of the Eukaryotic Ribosome

Ben-Shem, Adam, Jenner, Lasse, Yusupova, Gulnara, Yusupov, Marat·2010·Science

Abstract

Macromolecular Message Translation: The ribosome is a macromolecular machine that translates the sequence of messenger RNA into proteins in all living cells. Structures of prokaryotic ribosomes have supplied insight into the conserved features of such protein synthesis; however, eukaryotic translation has additional levels of complexity. Ben-Shem et al. (p. 1203 ) have determined the crystal structure of the yeast 80S ribosome at 4.15 angstrom resolution. The ribosome is in a ratcheted conformation, which is a state that is an intermediate in the translocation of messenger RNA and transfer RNA. The crystal structure provides the molecular underpinning for existing biochemical and genetic data and will inform the design of functional experiments.

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Crossref · 10.1126/science.1194294

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Metadata

Authors
Ben-Shem, A., Jenner, L., Yusupova, G., & Yusupov, M.
Venue
Science
Published
2010-11-26
Volume
330
Issue
6008
Pages
1203-1209
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2093705507
Cited by
422
References
2
FWCI
22.57
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Crystal Structure of the Eukaryotic Ribosome. https://app.cochat.ai/papers/10.1126/science.1194294
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Ben-Shem, A., Jenner, L., Yusupova, G., & Yusupov, M. (2010). Crystal Structure of the Eukaryotic Ribosome. Science. https://doi.org/10.1126/science.1194294

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