The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Two Histone Marks Establish the Inner Centromere and Chromosome Bi-Orientation
Abstract
Location, Location, Location: Cell division is orchestrated by a complex signaling pathway that ensures the correct segregation of newly replicated chromosomes to the two daughter cells. The pathway is controlled in part by restricting the activity of critical regulators to specific subcellular locations. For example, the chromosomal passenger complex (CPC) is recruited to chromosomes during mitosis where it oversees kinetochore activity and cytokinesis (see Perspective by Musacchio ). Wang et al. (p. 231 , published online 12 August), Kelly et al. (p. 235 , published online 12 August), and Yamagishi et al. (p. 239 ) now show that the phosphorylation of the chromatin protein, histone H3, acts to bring the CPC to chromosomes, thereby activating its aurora B kinase subunit. The Survivin subunit of CPC binds specifically to phosphorylated H3, with the phosphorylation at centromeres being carried out by the mitosis-specific kinase, haspin. Furthermore, Bub1 phosphorylation of histone H2A recruits shugoshin, a centromeric CPC adapter. Thus, these two histone marks in combination define the inner centromere.
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Hauf, S., Cole, R. W., LaTerra, S., Zimmer, C., Schnapp, G., Walter, R., Heckel, A., van Meel, J., Rieder, C. L., & Peters, J.-M. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200208092 · Cited by 1,155
The Conserved KMN Network Constitutes the Core Microtubule-Binding Site of the Kinetochore
Cheeseman, I. M., Chappie, J. S., Wilson-Kubalek, E. M., & Desai, A. (2006) · Cell · doi:10.1016/j.cell.2006.09.039 · Cited by 994
Chromosomal passengers: conducting cell division
Ruchaud, S., Carmena, M., & Earnshaw, W. C. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2257 · Cited by 811
Shugoshin collaborates with protein phosphatase 2A to protect cohesin
Kitajima, T. S., Sakuno, T., Ishiguro, K.-I., Iemura, S.-I., Natsume, T., Kawashima, S. A., & Watanabe, Y. (2006) · Nature · doi:10.1038/nature04663 · Cited by 597
Self-citationThe conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis
Kitajima, T. S., Kawashima, S. A., & Watanabe, Y. (2004) · Nature · doi:10.1038/nature02312 · Cited by 579
Self-citationThe cohesin complex and its roles in chromosome biology
Peters, J.-M., Tedeschi, A., & Schmitz, J. (2008) · Genes & Development · doi:10.1101/gad.1724308 · Cited by 532
Liu, D., Vader, G., Vromans, M. J. M., Lampson, M. A., & Lens, S. M. A. (2009) · Science · doi:10.1126/science.1167000 · Cited by 519
Phosphorylation of H2A by Bub1 Prevents Chromosomal Instability Through Localizing Shugoshin
Kawashima, S. A., Yamagishi, Y., Honda, T., Ishiguro, K.-I., & Watanabe, Y. (2010) · Science · doi:10.1126/science.1180189 · Cited by 476
Self-citationShugoshin Prevents Dissociation of Cohesin from Centromeres During Mitosis in Vertebrate Cells
McGuinness, B. E., Hirota, T., Kudo, N. R., Peters, J.-M., & Nasmyth, K. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030086 · Cited by 364
Salic, A., Waters, J. C., & Mitchison, T. J. (2004) · Cell · doi:10.1016/j.cell.2004.08.016 · Cited by 298
Cited by
Shared and separate functions of polo-like kinases and aurora kinases in cancer
Lens, S. M. A., Voest, E. E., & Medema, R. H. (2010) · Nature Reviews Cancer · doi:10.1038/nrc2964 · Cited by 597
Sensing centromere tension: Aurora B and the regulation of kinetochore function
Lampson, M. A., & Cheeseman, I. M. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2010.10.007 · Cited by 375
Cohesin and its regulation: on the logic of X-shaped chromosomes
Haarhuis, J. H. I., Elbatsh, A. M. O., & Rowland, B. D. (2014) · Developmental Cell · doi:10.1016/j.devcel.2014.09.010 · Cited by 147
WAPL-mediated removal of cohesin protects against segregation errors and aneuploidy
Haarhuis, J. H. I., Elbatsh, A. M. O., van den Broek, B., Camps, D., Erkan, H., Jalink, K., Medema, R. H., & Rowland, B. D. (2013) · Current Biology · doi:10.1016/j.cub.2013.09.003 · Cited by 84
Brimacombe, C. A., Burke, J. E., Parsa, J.-Y., Catania, S., O’Meara, T. R., Witchley, J. N., Burrack, L. S., Madhani, H. D., & Noble, S. M. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000331 · Cited by 22
Metadata
- Authors
- Yamagishi, Y., Honda, T., Tanno, Y., & Watanabe, Y.
- Venue
- Science
- Published
- 2010-10-08
- Volume
- 330
- Issue
- 6001
- Pages
- 239-243
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2091412272
- Cited by
- 466
- References
- 25
- FWCI
- 14.56
- Type
- journal article
- Language
- en
- Open access
- closed
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