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Cited by 1,223

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

Open access
The modENCODE Consortium, Roy, Sushmita, Ernst, Jason, Kharchenko, Peter V., Kheradpour, Pouya, Negre, Nicolas, Eaton, Matthew L., Landolin, Jane M., Bristow, Christopher A., Ma, Lijia, Lin, Michael F., Washietl, Stefan, Arshinoff, Bradley I., Ay, Ferhat, Meyer, Patrick E., Robine, Nicolas, Washington, Nicole L., Di Stefano, Luisa, Berezikov, Eugene, Brown, Christopher D., Candeias, Rogerio, Carlson, Joseph W., Carr, Adrian, Jungreis, Irwin, Marbach, Daniel, Sealfon, Rachel, Tolstorukov, Michael Y., Will, Sebastian, Alekseyenko, Artyom A., Artieri, Carlo, Booth, Benjamin W., Brooks, Angela N., Dai, Qi, Davis, Carrie A., Duff, Michael O., Feng, Xin, Gorchakov, Andrey A., Gu, Tingting, Henikoff, Jorja G., Kapranov, Philipp, Li, Renhua, MacAlpine, Heather K., Malone, John, Minoda, Aki, Nordman, Jared, Okamura, Katsutomo, Perry, Marc, Powell, Sara K., Riddle, Nicole C., Sakai, Akiko, Samsonova, Anastasia, Sandler, Jeremy E., Schwartz, Yuri B., Sher, Noa, Spokony, Rebecca, Sturgill, David, van Baren, Marijke, Wan, Kenneth H., Yang, Li, Yu, Charles, Feingold, Elise, Good, Peter, Guyer, Mark, Lowdon, Rebecca, Ahmad, Kami, Andrews, Justen, Berger, Bonnie, Brenner, Steven E., Brent, Michael R., Cherbas, Lucy, Elgin, Sarah C. R., Gingeras, Thomas R., Grossman, Robert, Hoskins, Roger A., Kaufman, Thomas C., Kent, William, Kuroda, Mitzi I., Orr-Weaver, Terry, Perrimon, Norbert, Pirrotta, Vincenzo, Posakony, James W., Ren, Bing, Russell, Steven, Cherbas, Peter, Graveley, Brenton R., Lewis, Suzanna, Micklem, Gos, Oliver, Brian, Park, Peter J., Celniker, Susan E., Henikoff, Steven, Karpen, Gary H., Lai, Eric C., MacAlpine, David M., Stein, Lincoln D., White, Kevin P., Kellis, Manolis, Acevedo, David, Auburn, Richard, Barber, Galt, Bellen, Hugo J., Bishop, Eric P., Bryson, Terri D., Chateigner, Aurelien, Chen, Jia, Clawson, Hiram, Comstock, Charles L. G., Contrino, Sergio, DeNapoli, Leyna C., Ding, Queying, Dobin, Alex, Domanus, Marc H., Drenkow, Jorg, Dudoit, Sandrine, Dumais, Jackie, Eng, Thomas, Fagegaltier, Delphine, Gadel, Sarah E., Ghosh, Srinka, Guillier, Francois, Hanley, David, Hannon, Gregory J., Hansen, Kasper D., Heinz, Elizabeth, Hinrichs, Angie S., Hirst, Martin, Jha, Sonali, Jiang, Lichun, Jung, Youngsook L., Kashevsky, Helena, Kennedy, Cameron D., Kephart, Ellen T., Langton, Laura, Lee, Ok-Kyung, Li, Sharon, Li, Zirong, Lin, Wei, Linder-Basso, Daniela, Lloyd, Paul, Lyne, Rachel, Marchetti, Sarah E., Marra, Marco, Mattiuzzo, Nicolas R., McKay, Sheldon, Meyer, Folker, Miller, David, Miller, Steven W., Moore, Richard A., Morrison, Carolyn A., Prinz, Joseph A., Rooks, Michelle, Moore, Richard, Rutherford, Kim M., Ruzanov, Peter, Scheftner, Douglas A., Senderowicz, Lionel, Shah, Parantu K., Shanower, Gregory, Smith, Richard, Stinson, E. O., Suchy, Sarah, Tenney, Aaron E., Tian, Feng, Venken, Koen J. T., Wang, Huaien, White, Robert, Wilkening, Jared, Willingham, Aarron T., Zaleski, Chris, Zha, Zheng, Zhang, Dayu, Zhao, Yongjun, Zieba, Jennifer·2010·Science
DOI 10.1126/science.1198374
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Abstract

From Genome to Regulatory Networks: For biologists, having a genome in hand is only the beginning—much more investigation is still needed to characterize how the genome is used to help to produce a functional organism (see the Perspective by Blaxter ). In this vein, Gerstein et al. (p. 1775 ) summarize for the Caenorhabditis elegans genome, and The modENCODE Consortium (p. 1787 ) summarize for the Drosophila melanogaster genome, full transcriptome analyses over developmental stages, genome-wide identification of transcription factor binding sites, and high-resolution maps of chromatin organization. Both studies identified regions of the nematode and fly genomes that show highly occupied targets (or HOT) regions where DNA was bound by more than 15 of the transcription factors analyzed and the expression of related genes were characterized. Overall, the studies provide insights into the organization, structure, and function of the two genomes and provide basic information needed to guide and correlate both focused and genome-wide studies.

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Metadata

Authors
The modENCODE Consortium, Roy, S., Ernst, J., Kharchenko, P. V., Kheradpour, P., Negre, N., Eaton, M. L., Landolin, J. M., Bristow, C. A., Ma, L., Lin, M. F., Washietl, S., Arshinoff, B. I., Ay, F., Meyer, P. E., Robine, N., Washington, N. L., Di Stefano, L., Berezikov, E., Brown, C. D., Candeias, R., Carlson, J. W., Carr, A., Jungreis, I., Marbach, D., Sealfon, R., Tolstorukov, M. Y., Will, S., Alekseyenko, A. A., Artieri, C., Booth, B. W., Brooks, A. N., Dai, Q., Davis, C. A., Duff, M. O., Feng, X., Gorchakov, A. A., Gu, T., Henikoff, J. G., Kapranov, P., Li, R., MacAlpine, H. K., Malone, J., Minoda, A., Nordman, J., Okamura, K., Perry, M., Powell, S. K., Riddle, N. C., Sakai, A., Samsonova, A., Sandler, J. E., Schwartz, Y. B., Sher, N., Spokony, R., Sturgill, D., van Baren, M., Wan, K. H., Yang, L., Yu, C., Feingold, E., Good, P., Guyer, M., Lowdon, R., Ahmad, K., Andrews, J., Berger, B., Brenner, S. E., Brent, M. R., Cherbas, L., Elgin, S. C. R., Gingeras, T. R., Grossman, R., Hoskins, R. A., Kaufman, T. C., Kent, W., Kuroda, M. I., Orr-Weaver, T., Perrimon, N., Pirrotta, V., Posakony, J. W., Ren, B., Russell, S., Cherbas, P., Graveley, B. R., Lewis, S., Micklem, G., Oliver, B., Park, P. J., Celniker, S. E., Henikoff, S., Karpen, G. H., Lai, E. C., MacAlpine, D. M., Stein, L. D., White, K. P., Kellis, M., Acevedo, D., Auburn, R., Barber, G., Bellen, H. J., Bishop, E. P., Bryson, T. D., Chateigner, A., Chen, J., Clawson, H., Comstock, C. L. G., Contrino, S., DeNapoli, L. C., Ding, Q., Dobin, A., Domanus, M. H., Drenkow, J., Dudoit, S., Dumais, J., Eng, T., Fagegaltier, D., Gadel, S. E., Ghosh, S., Guillier, F., Hanley, D., Hannon, G. J., Hansen, K. D., Heinz, E., Hinrichs, A. S., Hirst, M., Jha, S., Jiang, L., Jung, Y. L., Kashevsky, H., Kennedy, C. D., Kephart, E. T., Langton, L., Lee, O.-K., Li, S., Li, Z., Lin, W., Linder-Basso, D., Lloyd, P., Lyne, R., Marchetti, S. E., Marra, M., Mattiuzzo, N. R., McKay, S., Meyer, F., Miller, D., Miller, S. W., Moore, R. A., Morrison, C. A., Prinz, J. A., Rooks, M., Moore, R., Rutherford, K. M., Ruzanov, P., Scheftner, D. A., Senderowicz, L., Shah, P. K., Shanower, G., Smith, R., Stinson, E. O., Suchy, S., Tenney, A. E., Tian, F., Venken, K. J. T., Wang, H., White, R., Wilkening, J., Willingham, A. T., Zaleski, C., Zha, Z., Zhang, D., Zhao, Y., & Zieba, J.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2010-12-24
Volume
330
Issue
6012
Pages
1787-1797
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.1198374
OpenAlex
W2084191969
Cited by
1,223
References
7
FWCI
43.01
Type
journal article
Language
en
Open access
green

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