A Family of IFN-γ–Inducible 65-kD GTPases Protects Against Bacterial Infection

Kim, Bae-Hoon, Shenoy, Avinash R., Kumar, Pradeep, Das, Rituparna, Tiwari, Sangeeta, MacMicking, John D.·2011·Science

DOI 10.1126/science.1201711

Cited by (494)

Items 201–300 of 494

Mitochondria in autoinflammation: cause, mediator or bystander?
Robert van der Burgh, Marianne L. Boes · 2015 · Trends in Endocrinology and Metabolism
Pathogen-Induced Autophagy Signaling in Innate Immunity
Mathias Faure, Frank Lafont · 2013 · Journal of Innate Immunity
The roles of microRNAs in regulation of autophagy during bacterial infection
Prashanta Silwal, Yi Sak Kim, Joyoti Basu, Eun‐Kyeong Jo · 2019 · Seminars in Cell and Developmental Biology
Role of GBP1 in innate immunity and potential as a tuberculosis biomarker
Ting Shi, Linlin Huang, Yulin Zhou, Jianmei Tian · 2022 · Scientific Reports
Antimicrobial inflammasomes: unified signalling against diverse bacterial pathogens
Matthew J. G. Eldridge, Avinash R. Shenoy · 2014 · Current Opinion in Microbiology
A Novel, 5-Transcript, Whole-blood Gene-expression Signature for Tuberculosis Screening Among People Living With Human Immunodeficiency Virus
Jayant V. Rajan, Fred Collins Semitala, Tejas Mehta, Mark T. Seielstad, Lani Montalvo, Alfred Onubia Andama, Lucy Asege, Martha Nakaye, Jane Katende, Sandra Z. Mwebe et al. · 2018 · Clinical Infectious Diseases
Mechanisms of interferon-beta-induced inhibition ofToxoplasma gondiigrowth in murine macrophages and embryonic fibroblasts: role of immunity-related GTPase M1
Motamed Elsayed Mahmoud, Fumiki Ui, Doaa Salman, Maki Nishimura, Yoshifumi Nishikawa · 2015 · Cellular Microbiology
Transcriptomic Analysis of Persistent Infection with Foot-and-Mouth Disease Virus in Cattle Suggests Impairment of Apoptosis and Cell-Mediated Immunity in the Nasopharynx
Michael Eschbaumer, Carolina Stenfeldt, George R. Smoliga, Juan M. Pacheco, Luis L. Rodrı́guez, Robert W. Li, James J. Zhu, Jonathan Arzt · 2016 · PLoS ONE
The role of host autophagy machinery in controllingToxoplasmainfection
Sébastien Besteiro · 2018 · Virulence
Genetic architecture of gene expression underlying variation in host response to porcine reproductive and respiratory syndrome virus infection
Arun Kommadath, Hua Bao, Igseo Choi, James Mark Reecy, James Eugene Koltes, Elyn Fritz‐Waters, Chris J. Eisley, Jason R. Grant, Robert R. R. Rowland, Christopher Keith Tuggle et al. · 2017 · Scientific Reports
Interferon-Induced Guanylate-Binding Proteins Promote Cytosolic Lipopolysaccharide Detection by Caspase-11
Étienne Meunier, Petr Brož · 2014 · DNA and Cell Biology
Down regulation of macrophage IFNGR1 exacerbates systemic L. monocytogenes infection
Emily M. Eshleman, Christine Delgado, Staci J. Kearney, Rachel Sharon Friedman, Laurel L. Lenz · 2017 · PLoS Pathogens
Analysis of the Atlantic salmon genome reveals a cluster of Mx genes that respond more strongly to IFN gamma than to type I IFN
Børre Robertsen, Linn Greiner-Tollersrud, Lars Gaute Jørgensen · 2018 · Developmental & Comparative Immunology
Macrophages inhibit Coxiella burnetii by the ACOD1‐itaconate pathway for containment of Q fever
Lisa Kohl, Md Nur A Alam Siddique, Barbara Bodendorfer, Raffaela S. Berger, Annica Preikschat, Christoph Daniel, Martha Ölke, Elisabeth Liebler–Tenorio, Jan Schulze‐Luehrmann, Michael Mauermeir et al. · 2022 · EMBO Molecular Medicine
Interferon-γ in Salmonella pathogenesis: New tricks for an old dog
Justin P. Ingram, Igor E. Brodsky, Siddharth Balachandran · 2016 · Cytokine
Guanylate-binding proteins at the crossroad of noncanonical inflammasome activation during bacterial infections
Marco Túlio R. Gomes, Daiane M. Cerqueira, Erika Sousa Guimarães, Priscila Carneiro Campos, Sergio Costa Oliveira · 2019 · Journal of Leukocyte Biology
Mechanisms of Memory T Cell Activation and Effective Immunity
Gregoire S. Lauvau, Saïdi M. Soudja · 2015 · Advances in experimental medicine and biology
Expression of nuclear factor, erythroid 2-like 2-mediated genes differentiates tuberculosis
Zhongqing Qian, Jingzhu Lv, Gabriel T. Kelly, Hongtao Wang, Xiaojie Zhang, Wanjun Gu, Xiaofeng Yin, Ting Wang, Tong Zhou · 2016 · Tuberculosis
Growth hormone-mediated reprogramming of macrophage transcriptome and effector functions
Augusto Schneider, Hillary N. Wood, Sandra E. Geden, Catherine J. Greene, Robin M. Yates, Michał M. Masternak, Kyle H. Rohde · 2019 · Scientific Reports
Inducible Guanylate-Binding Protein 7 Facilitates Influenza A Virus Replication by Suppressing Innate Immunity via NF-κB and JAK-STAT Signaling Pathways
Mingkai Feng, Qiao Zhang, Wenjiao Wu, Lizhu Chen, Shuyin Gu, Yilu Ye, Yingyuan Zhong, Qi Huang, Shuwen Liu · 2021 · Journal of Virology
Genome-wide transcriptional analysis of differentially expressed genes in flagellin-pretreated mouse corneal epithelial cells in response to Pseudomonas aeruginosa: involvement of S100A8/A9
Nan Gao, Gi Sang Yoon, Xiaonan Liu, Xiaofan Mi, W Chen, T J Standiford, F-SX Yu · 2013 · Mucosal Immunology
Unveiling the pathogen behind the vacuole
Peter Liehl, Vanessa Zuzarte‐Luís, Maria M. Mota · 2015 · Nature Reviews Microbiology
SNX8 mediates IFNγ-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes
Jin Wei, Wei Guo, Huan Lian, Qing Yang, Heng Lin, Shu Li, Hong‐Bing Shu · 2017 · Proceedings of the National Academy of Sciences
Identification of a systemic interferon-γ inducible antimicrobial gene signature in leprosy patients undergoing reversal reaction
Rosane M. B. Teles, Jing Nan Lu, Maria Tió‐Coma, Isabela Maria Bernardes Goulart, Sayera Banu, Deanna A. Hagge, Kidist Bobosha, Tom H. M. Ottenhoff, Matteo A. Pellegrini, Annemieke Geluk et al. · 2019 · PLoS neglected tropical diseases
Structural basis of antimicrobial membrane coat assembly by human GBP1
Tanja Kuhm, Clémence Taisne, Cecilia de Agrela Pinto, Luca Gross, Evdokia‐Anastasia Giannopoulou, Stefan T. Huber, Els Pardon, Jan Steyaert, Sander J. Tans, Arjen J. Jakobi · 2024 · Nature Structural & Molecular Biology
Caspase-11 Non-canonical Inflammasomes in the Lung
Changhoon Oh, Ambika Verma, Youssef Aachoui · 2020 · Frontiers in Immunology
Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection
Nora Steffens, Cornelia Beuter-Gunia, Elisabeth Kravets, Artur Reich, Larissa Legewie, Klaus Pfeffer, Daniel Degrandi · 2020 · mBio
Eimeria falciformis infection of the mouse caecum identifies opposing roles of IFNγ-regulated host pathways for the parasite development
Manuela Schmid, Emanuel G Heitlinger, Simone Spork, Hans‐Joachim Mollenkopf, Richard Lucius, Nishith Gupta · 2013 · Mucosal Immunology
Sweet host revenge: Galectins and GBPs join forces at broken membranes
Jörn Coers · 2017 · Cellular Microbiology
Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion
David E. Place, Benoit Briard, Parimal Samir, Rajendra Karki, Anannya Bhattacharya, Clifford S. Guy, Jennifer L. Peters, Sharon Frase, Peter Vogel, Geoffrey A. M. Neale et al. · 2020 · PLoS Pathogens
Functional cross-species conservation of guanylate-binding proteins in innate immunity
Luca Schelle, João Vasco Côrte‐Real, Pedro José Esteves, Joana Abrantes, Hanna‐Mari Baldauf · 2022 · Medical Microbiology and Immunology
In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
Venugopal, Gopinath, Bird, Jordan T., Washam, Charity L., Roys, Hayden, Bowlin, Anne, Byrum, Stephanie D., Weinkopff, Tiffany · 2022 · PLOS Neglected Tropical Diseases
Interactions of Autophagy and the Immune System in Health and Diseases
Aarti Pant, Xiaomin Yao, Aude Lavedrine, Christophe Viret, Jacob Dockterman, Swati C. Chauhan, Chong-Shan Shi, Ravi R. Manjithaya, Ken Cadwell, Thomas A. Kufer et al. · 2022 · Autophagy Reports
Antimicrobial effects of murine mesenchymal stromal cells directed against Toxoplasma gondii and Neospora caninum: role of immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs)
Katrin Spekker, Margret Leineweber, Daniel Degrandi, Vanessa Ince, S. Brunder, Silvia K. Schmidt, Silke Stuhlsatz, Jonathan Charles Howard, Gereon Schares, Özer Degistirici et al. · 2012 · Medical Microbiology and Immunology
Transcriptional Profiling of Foam Cells Reveals Induction of Guanylate‐Binding Proteins Following Western Diet Acceleration of Atherosclerosis in the Absence of Global Changes in Inflammation
Young‐Hwa Goo, Se‐Hee Son, Vijay K. Yechoor, Antoni Paul · 2016 · Journal of the American Heart Association
The large GTPase AtGBPL3 links nuclear envelope formation and morphogenesis to transcriptional repression
Theresa Maria Reimann, Christina Müdsam, Christina Schachtler, Semra Ince, Heinrich Sticht, Christian Herrmann, Michael Stürzl, Benedikt Kost · 2023 · Nature Plants
Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections
Staci J. Kearney, Christine Delgado, Laurel L. Lenz · 2012 · Immunologic Research
IFN-γ alters the expression of diverse immunity related genes in a cell culture model designed to represent maturing neutrophils
Michael A. Ellison, Christy M. Gearheart, Christopher C. Porter, Daniel R. Ambruso · 2017 · PLoS ONE
RDH1 suppresses adiposity by promoting brown adipose adaptation to fasting and re-feeding
Charles R. Krois, Marta G. Vuckovic, Priscilla Huang, Claire Zaversnik, Conan S. Liu, Candice E. Gibson, Madelyn R. Wheeler, Kristin M. Obrochta, Jin H. Min, Candice B. Herber et al. · 2019 · Cellular and Molecular Life Sciences
Proteomic Characterization of the Cellular Response to Nitrosative Stress Mediated by S-Nitrosoglutathione Reductase Inhibition
Matthew W. Foster, Zhonghui Yang, David M. Gooden, J. Will Thompson, Carol H. Ball, Meredith E. Turner, Yongyong Hou, Jingbo Pi, Martin Arthur Moseley, Loretta G. Que · 2012 · Journal of Proteome Research
Neutrophils and galectin-3 defend mice from lethal bacterial infection and humans from acute respiratory failure
Sudipta Das, Tomasz Waldemar Kaminski, Brent Thomas Schlegel, William Bain, Sanmei Hu, Akruti Patel, Sagar Laxman Kale, Kong Chen, Janet S. Lee, Rama K. Mallampalli et al. · 2024 · Nature Communications
Cooperation of TRADD- and RIPK1-dependent cell death pathways in maintaining intestinal homeostasis
Ziyu Sun, Jiaxing Ye, Wei Jia Sun, Libo Jiang, Bing Shan, Mengmeng Zhang, Jingyi Xu, Wanjin Li, Jianping Liu, Hongyang Jing et al. · 2025 · Nature Communications
Genetic Regulation of Guanylate-Binding Proteins 2b and 5 during Leishmaniasis in Mice
Yahya Sohrabi, Valeryia Volkova, Tatyana Kobets, Helena Havelková, Imtissal Krayem, Martina Slapničková, Peter Démant, Marie Lipoldová · 2018 · Frontiers in Immunology
Integrative dynamic structural biology unveils conformers essential for the oligomerization of a large GTPase
Thomas-Otavio Peulen, Carola S. Hengstenberg, Ralf Biehl, Mykola Dimura, Charlotte Lorenz, Alessandro Valeri, Julian Folz, Christian A. Hanke, Semra Ince, Tobias Vöpel et al. · 2023 · eLife
MxA suppresses TAK1-IKKα/β-NF-κB mediated inflammatory cytokine production to facilitate Mycobacterium tuberculosis infection
Xinying Zhou, Lijie Zhang, Linmiao Lie, Zelin Zhang, Bo Zhu, Jiahui Yang, Yuchi Gao, Pengfei Li, Yingqi Huang, Hui Xu et al. · 2020 · Journal of Infection
Interferon-induced GTPases orchestrate host cell-autonomous defence against bacterial pathogens
Heike L. Rafeld, Waldemar Kolanus, Ian Richard van Driel, Elizabeth Louise Hartland · 2021 · Biochemical Society Transactions
Peganum harmala Extract Has Antiamoebic Activity to Acanthamoeba triangularis Trophozoites and Changes Expression of Autophagy-Related Genes
Rachasak Boonhok, Suthinee Sangkanu, Julalak Chuprom, Mayuna Srisuphanunt, Roghayeh Norouzi, Abolghasem Siyadatpanah, Farzaneh Mirzaei, Watcharapong Mitsuwan, Sueptrakool Wisessombat, Maria de Lourdes Pereira et al. · 2021 · Pathogens
In vivo interferon-gamma induced changes in gene expression dramatically alter neutrophil phenotype
Daniel R. Ambruso, Natalie J. Briones, Angelina Baroffio, John R. Murphy, Alexander D. Tran, Katherine Gowan, Bridget L. Sanford, Michael A. Ellison, Kenneth L. Jones · 2022 · PLoS ONE
Human GBP1 facilitates the rupture of the Legionella- containing vacuole and inflammasome activation
Antonia R Bass, Marisa S. Egan, Jasmine Alexander-Floyd, Natasha Lopes Fischer, Jessica Doerner, Sunny Shin · 2023 · mBio
Broad recruitment of mGBP family members to Chlamydia trachomatis inclusions
Valesca Lindenberg, Katja Mölleken, Elisabeth Kravets, Sonja Stallmann, Johannes H. Hegemann, Daniel Degrandi, Klaus Pfeffer · 2017 · PLoS ONE
Partners in anti-crime: how interferon-inducible GTPases and autophagy proteins team up in cell-intrinsic host defense
Jörn Coers, Hailey M. Brown, Seungmin Hwang, Gregory Alan Taylor · 2018 · Current Opinion in Immunology
Surviving the Macrophage: Tools and Tricks Employed by Mycobacterium tuberculosis
Rajesh Jayachandran, Somdeb Bose Dasgupta, Jean Pieters · 2012 · Current topics in microbiology and immunology
Tupaia GBP1 Interacts with STING to Initiate Autophagy and Restrict Herpes Simplex Virus Type 1 Infection
Tianle Gu, Dandan Yu, Ling Xu, Yulin Yao, Yong‐Gang Yao · 2021 · The Journal of Immunology
Toxoplasma -proximal and distal control by GBPs in human macrophages
Daniel Fisch, Barbara Clough, Rabia Tahir Khan, Lyn E. Healy, Eva‐Maria Frickel · 2021 · Pathogens and Disease
Neoantigen Presentation and IFNγ Signaling on the Same Tumor-associated Macrophage are Necessary for CD4 T Cell–mediated Antitumor Activity in Mice
Ainhoa Pérez‐Díez, Xiangdong Liu, Polly Matzinger · 2022 · Cancer Research Communications
Expression profiling of the GBP 1 gene as a candidate gene for porcine reproductive and respiratory syndrome resistance
S. Gol, J. Estany, Lorenzo José Fraile, Ramona N. Pena · 2015 · Animal Genetics
Molecular identification and antiviral function of the guanylate-binding protein (GBP) genes in the Chinese tree shrew (Tupaia belangeri chinesis)
Tianle Gu, Dandan Yu, Yu Fan, Yong Wu, Yulin Yao, Ling Xu, Yong‐Gang Yao · 2019 · Developmental & Comparative Immunology
Transcriptome analysis of human brain microvascular endothelial cells response to Neisseria meningitidis and its antigen MafA using RNA-seq
Evelína Káňová, Zuzana Tkáčová, Katarína Bhide, Amod D. Kulkarni, Irene Jiménez-Munguía, Patrícia Petroušková, Monika Drážovská, Punit Tyagi, Mangesh Ramesh Bhide · 2019 · Scientific Reports
Suppressor of cytokine signalling protein SOCS1 and UBP43 regulate the expression of type I interferon-stimulated genes in human microvascular endothelial cells infected with Rickettsia conorii
Punsiri M. Colonne, Abha Sahni, Sangita Sahni · 2013 · Journal of Medical Microbiology
Correction to “Proteomic Characterization of the Cellular Response to Nitrosative Stress Mediated by S-Nitrosoglutathione Reductase Inhibition”
Matthew W. Foster, Zhonghui Yang, David M. Gooden, J. Will Thompson, Carol H. Ball, Meredith E. Turner, Yongyong Hou, Jingbo Pi, Martin Arthur Moseley, Loretta G. Que · 2017 · Journal of Proteome Research
Maternal natural killer cells drive neuroimmune disorders in offspring through aberrant secretion of extracellular granzyme B
Qiwu Bian, Yihang Chen, Jinghe Zhang, Xianghui Du, Yonggang Zhou, Qiao Zhang, Chen Ding, Haiming Wei, Binqing Fu · 2025 · Immunity
The AlternativeTranslational Profile That Underlies the Immune-Evasive State of Persistence in Chlamydiaceae Exploits Differential Tryptophan Contents of the Protein Repertoire
Chien‐Chi Lo, Gary G. Xie, Carol A. Bonner, Roy A. Jensen · 2012 · Microbiology and Molecular Biology Reviews
Francisella Inflammasomes: Integrated Responses to a Cytosolic Stealth Bacterium
Pierre Wallet, Brice Lagrange, Thomas Henry · 2016 · Current topics in microbiology and immunology
Gene expression profiles of putative biomarker candidates inMycobacterium aviumsubsp.paratuberculosis-infected cattle
Hyun-Eui Park, Min‐Kyoung Shin, Hong-Tae Park, Myunghwan Jung, Yong-Il Cho, Han Sang Yoo · 2016 · Pathogens and Disease
Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
Ambika Verma, Gohar Azhar, Pankaj Patyal, Wei Zhang, Xiaomin Zhang, Jeanne Y. Wei · 2024 · GeroScience
Evolution of Cell-Autonomous Effector Mechanisms in Macrophages versus Non-Immune Cells
Ryan G. Gaudet, Clinton J. Bradfield, John D. MacMicking · 2016 · Microbiology Spectrum
Calcimycin induced IL-12 production inhibits intracellular mycobacterial growth by enhancing autophagy
Shradha Mawatwal, Assirbad Behura, Abtar Mishra, Ramandeep Singh, Rohan Dhiman · 2018 · Cytokine
Partial human Janus kinase 1 deficiency predominantly impairs responses to interferon gamma and intracellular control of mycobacteria
Vanessa Daza-Cajigal, Adriana S. Albuquerque, Dan F. Young, Michael J. Ciancanelli, DALE A. MOULDING, Ivan Angulo, Valentine Jeanne-Julien, Jérémie Rosain, Ekaterina Minskaia, Jean‐Laurent Casanova et al. · 2022 · Frontiers in Immunology
Role of Ets Proteins in Development, Differentiation, and Function of T‐Cell Subsets
Mian Liu, Weiwu Gao, Jennifer C. van Velkinburgh, Yuzhang Wu, Bing Ni, Yi Tian · 2015 · Medicinal Research Reviews
Striking the Right Balance Determines TB or Not TB
Somdeb Bose Dasgupta, Jean Pieters · 2014 · Frontiers in Immunology
Modification of the host ubiquitome by bacterial enzymes
Jennifer Berglund, Rafaela Gjondrekaj, Ellen Verney, Julie Anne Maupin-furlow, Mariola J. Edelmann · 2020 · Microbiological Research
Vitamin D – A host directed autophagy mediated therapy for tuberculosis
Krisna Moorthi Periyasamy, Uma Devi Ranganathan, Srikanth Prasad Tripathy, Ramalingam Bethunaickan · 2020 · Molecular Immunology
Host Cell Autophagy in Immune Response to Zoonotic Infections
Panagiotis Skendros, Ioannis Mitroulis · 2011 · Clinical and Developmental Immunology
Quo vadis? Interferon-inducible GTPases go to their target membranes via the LC3-conjugation system of autophagy
Jayoung Choi, Scott B. Biering, Seungmin Hwang · 2016 · Small GTPases
Immune checkpoint modulating T cells and NK cells response to Mycobacterium tuberculosis infection
Yongwei Qin, Qinglan Wang, Jiahai Shi · 2023 · Microbiological Research
Processing and secretion of guanylate binding protein‐1 depend on inflammatory caspase activity
Elisabeth Naschberger, Walter Geißdörfer, Christian Bogdan, Philipp Tripal, Elisabeth Kremmer, Michael Stürzl, Nathalie Britzen‐Laurent · 2017 · Journal of Cellular and Molecular Medicine
A Nonpyroptotic IFN-γ–Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Salmonella Clearance In Vivo
Justin P. Ingram, Sarah A. Tursi, Ting Zhang, Wei Guo, Chaoran Yin, Meghan A. Wynosky-Dolfi, Joris van der Heijden, Kathy Qi Cai, Masahiro Yamamoto, B. Brett Finlay et al. · 2018 · The Journal of Immunology
Guanylate binding proteins contained in the murine chromosome 3 are important to control mycobacterial infection
Fabio Vitarelli Marinho, Júlia S. Fahel, Ana Carolina V. S. C. de Araujo, Lunna Honorato Diniz, Marco Túlio R. Gomes, Danilo Pires Resende, Ana Paula Junqueira‐Kipnis, Sergio Costa Oliveira · 2020 · Journal of Leukocyte Biology
Host Transcriptional Profiles and Immunopathologic Response following Mycobacterium avium subsp. paratuberculosis Infection in Mice
Min‐Kyoung Shin, Hong-Tae Park, Seungwon Shin, Myunghwan Jung, Su‐Hyung Lee, Dae-Yong Kim, Han Sang Yoo · 2015 · PLoS ONE
Altered IFN-γ–Mediated Immunity and Transcriptional Expression Patterns in N-Ethyl-N-Nitrosourea–Induced STAT4 Mutants Confer Susceptibility to Acute Typhoid-like Disease
Megan M. Eva, Kyoko E. Yuki, Shauna M. Dauphinee, Jeremy Schwartzentruber, Michał Pyzik, Marilène Paquet, Mark G. Lathrop, Jacek Majewski, Silvia Marina Vidal, Danielle Malo · 2013 · The Journal of Immunology
Belowground Microbial Crosstalk and Rhizosphere Biology
Satyavir Singh Sindhu, Anju Sehrawat, Ruchi Sharma, Anupma Dahiya, Aakanksha Khandelwal · 2017 · Springer eBooks
Ubiquitination of pathogen-containing vacuoles promotes host defense to Chlamydia trachomatis and Toxoplasma gondii
Jörn Coers, Arun Kumar Haldar · 2015 · Communicative & Integrative Biology
MyD88 Is Required for Efficient Control of Coxiella burnetii Infection and Dissemination
Lisa Kohl, Inaya Hayek, Christoph Daniel, Jan Schulze‐Luehrmann, Barbara Bodendorfer, Anja Lührmann, Roland Lang · 2019 · Frontiers in Immunology
Induction of Acquired Resistance towards EGFR Inhibitor Gefitinib in a Patient-Derived Xenograft Model of Non-Small Cell Lung Cancer and Subsequent Molecular Characterization
Julia B. Schüler, Cordula Tschuch, Kerstin Klingner, Daniel Bug, Anne-Lise Peille, Leanne de Koning, Eva Oswald, Hagen Klett, Wolfgang Sommergruber · 2019 · Cells
Oxygen-independent free radical generation mediated by core-shell magnetic nanocomposites synergizes with immune checkpoint blockade for effective primary and metastatic tumor treatment
Jincheng Guo, Qiao An, Mengyu Guo, Yating Xiao, Bo Li, Fene Gao, Yuqing Wang, Jiayang Li, Yaling Wang, Ying Liu et al. · 2020 · Nano Today
Chemotherapy‐induced phlebitis via the GBP5/NLRP3 inflammasome axis and the therapeutic effect of aescin
Peng Liu, Lichun Ye, Yongshen Ren, Guodun Zhao, Yun Zhang, Shaojuan Lu, Qiang Li, Chen Wu, Lijie Bai, Zhongyun Zhang et al. · 2022 · British Journal of Pharmacology
Emerging Functions of Autophagy in Kidney Transplantation
Nicolas Pallet, Man Jiang Livingston, Zheng Dong · 2013 · American Journal of Transplantation
Human Alveolar and Splenic Macrophage Populations Display a Distinct Transcriptomic Response to Infection With Mycobacterium tuberculosis
Lelia Lavalett, Héctor Ortega, Luis Fernando Barrera · 2020 · Frontiers in Immunology
Evaluation of Host Protein Biomarkers by ELISA From Whole Lysed Peripheral Blood for Development of Diagnostic Tests for Active Tuberculosis
Harriet N. Garlant, Kalaiarasan Ellappan, Matthew Hewitt, Prem Perumal, Simon Pekeleke, Nadina I. Vasileva Wand, Jo Southern, Saka Vinod Kumar, Belgode Narasimha Harish, Ibrahim Abubakar et al. · 2022 · Frontiers in Immunology
Effect of the dietary supplementation with extracts of chestnut wood and grape pomace on performance and jejunum response in female and male broiler chickens at different ages
A. Pascual, Marianna Pauletto, A. Trocino, Marco Birolo, Mauro Dacasto, Mery Giantin, Francesco Bordignon, Cristina Ballarin, Martina Bortoletti, Giulio Pillan et al. · 2022 · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
Mycobacterium tuberculosis Evasion of Guanylate Binding Protein-Mediated Host Defense in Mice Requires the ESX1 Secretion System
Andrew J. Olive, Clare M. Smith, Christina E. Baer, Jörn Coers, Christopher M. Sassetti · 2023 · International Journal of Molecular Sciences
Gene expression QTL mapping in stimulated iPSC-derived macrophages provides insights into common complex diseases
Nikolaos I. Panousis, Omar El Garwany, Andrew J. Knights, Jesse Rop, Natsuhiko Kumasaka, Maria Imaz, Lorena Boquete Vilarino, A. Tsingene, Alex Tokolyi, Alice Barnett et al. · 2025 · Nature Communications
Dual RNASeq Reveals NTHi-Macrophage Transcriptomic Changes During Intracellular Persistence
Jodie Ackland, Ashley Heinson, David William Cleary, Myron Christodoulides, Tom M. A. Wilkinson, Karl J. Staples · 2021 · Frontiers in Cellular and Infection Microbiology
Coexpression Network Analysis-Based Identification of Critical Genes Differentiating between Latent and Active Tuberculosis
Liang Chen, Jie Hua, Xiaopu He · 2022 · Disease Markers
Human GBP1 Is Involved in the Repair of Damaged Phagosomes/Endolysosomes
Hellen Buijze, Volker Brinkmann, ROBERT M. HURWITZ, Anca Dorhoi, Stefan H. E. Kaufmann, Gang Pei · 2023 · International Journal of Molecular Sciences
Formalin-evoked pain triggers sex-specific behavior and spinal immune response
Lucie Pepino, Pascale Malapert, Andrew J. Saurin, Aziz Moqrich, Ana Reynders · 2023 · Scientific Reports
Autophagy facilitates cytokine-induced ICAM-1 expression
Chi‐Yun Wang, Tzu-Hui Chiang, Chia‐Ling Chen, Po‐Chun Tseng, Shun-Yi Chien, Yi-Jui Chuang, Tsan-Tzu Yang, Chia-Yuan Hsieh, Pui-Ching Choi, Chiou‐Feng Lin · 2013 · Innate Immunity
Differential expression of interferon inducible protein: Guanylate binding protein (GBP1 & GBP2) in severe dengue
Vignesh Mariappan, Shalinda Adikari, S. Lokesh, Joshy Maducolil Easow, Agieshkumar Balakrishna Pillai · 2022 · Free Radical Biology and Medicine
Role of genetic factors in different swine breeds exhibiting varying levels of resistance/susceptibility to PRRSV
Xiangbin You, Li Gan, Ying Lei, Zhiqian Xu, Ping Zhang, Youbing Yang · 2023 · Virus Research
Age-Dependent Differences in Systemic and Cell-Autonomous Immunity toL. monocytogenes
Ashley M. Sherrid, Tobias R. Kollmann · 2013 · Clinical and Developmental Immunology