A Family of IFN-γ–Inducible 65-kD GTPases Protects Against Bacterial Infection

Human IRGM Induces Autophagy to Eliminate Intracellular Mycobacteria

Singh, S. B., Davis, A. S., Taylor, G. A., & Deretic, V. (2006) · Science · doi:10.1126/science.1129577 · Cited by 915

Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47

MacMicking, J. D., Taylor, G. A., & McKinney, J. D. (2003) · Science · doi:10.1126/science.1088063 · Cited by 685

An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure

Fujita, N., Hayashi, M., Fukumoto, H., Omori, H., Yamamoto, A., Noda, T., & Yoshimori, T. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-03-0312 · Cited by 527

p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding

Itakura, E., & Mizushima, N. (2011) · The Journal of Cell Biology · doi:10.1083/jcb.201009067 · Cited by 430

Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis

Sever, S., Muhlberg, A. B., & Schmid, S. L. (1999) · Nature · doi:10.1038/19024 · Cited by 367

Inborn errors of interferon (IFN)‐mediated immunity in humans: insights into the respective roles of IFN‐α/β, IFN‐γ, and IFN‐λ in host defense

Zhang, S., Boisson‐Dupuis, S., Chapgier, A. L. A., Yang, K., Bustamante, J. C., Puel, A., Pïcard, C., Abel, L., Jouanguy, E., & Casanova, J. (2008) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00698.x · Cited by 334

Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins

Prakash, B., Praefcke, G. J. K., Renault, L., Wittinghofer, A., & Herrmann, C. (2000) · Nature · doi:10.1038/35000617 · Cited by 323

Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagy

Alonso, S., Pethe, K., Russell, D. G., & Purdy, G. E. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700036104 · Cited by 318

Delivery of Cytosolic Components by Autophagic Adaptor Protein p62 Endows Autophagosomes with Unique Antimicrobial Properties

Ponpuak, M., Davis, A. S., Roberts, E. A., Delgado, M. A., Dinkins, C., Zhao, Z., Virgin, H. W., Kyei, G. B., Johansen, T., Vergne, I., et al. (2010) · Immunity · doi:10.1016/j.immuni.2010.02.009 · Cited by 309

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

Bekpen, C., Hunn, J. P., Rohde, C., Parvanova, I., Guethlein, L., Dunn, D. M., Glowalla, E., Leptin, M., & Howard, J. C. (2005) · Genome biology · doi:10.1186/gb-2005-6-11-r92 · Cited by 308

Evolution of Cell-Autonomous Effector Mechanisms in Macrophages versus Non-Immune Cells

Gaudet, R. G., Bradfield, C. J., & MacMicking, J. D. (2017) · ASM Press eBooks · doi:10.1128/9781555819194.ch34 · Cited by 2

Insights into the effect of guanylate-binding protein 1 on the survival of Brucella intracellularly

Li, Z., Wang, S., Han, J., Yang, G., Xi, L., Zhang, C., Cui, Y., Yin, S., Zhang, H., & Zhang, H. (2024) · Veterinary Microbiology · doi:10.1016/j.vetmic.2024.110089 · Cited by 2

Development and application of classical genetics in Toxoplasma gondii

Behnke, M. S., Saeij, J. P. J., & Boyle, J. P. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815041-2.00019-0 · Cited by 2

Human GBP1 promotes pathogen vacuole rupture and inflammasome activation during Legionella pneumophila infectionPreprint

Bass, A. R., & Shin, S. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.27.120477 · Cited by 2

Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophagesPreprint

Egan, M. S., O'Rourke, E. A., Mageswaran, S. K., Zuo, B., Martynyuk, I., Demissie, T., Hunter, E. N., Bass, A. R., Chang, Y., Brodsky, I. E., et al. (2023) · eLife · doi:10.7554/elife.90107.1 · Cited by 2

Lactiplantibacillus plantarum YY‐112 ameliorates mouse immunosuppression by enhancing B/T‐cell activation and maintaining Th1/Th2 homeostasis

Yang, Y., Luo, M., Zhou, W., Tao, W., Li, J., Xing, J., Tan, Q., & Guo, Y. (2024) · Food Frontiers · doi:10.1002/fft2.477 · Cited by 1

Identification of GBP6 as a potential prognostic biomarker in esophageal carcinoma by integrated bioinformatics analysis and experiment validation

Fang, S., Ding, Y., Jia, Y., Gao, L., Ning, Y., Wu, G., Fang, J., Zhang, Y., Wang, H., & Ke, H. (2025) · Annals of Medicine · doi:10.1080/07853890.2025.2521451 · Cited by 1

Inflammasome Activation Differences Underpin Different Mycobacterium tuberculosis Infection Outcomes

Kumar, R., Kolloli, A., Bhargavi, G., Husain, S., Chang, T. L.-Y., Ghanny, S., Soteropoulos, P., & Subbian, S. (2025) · MedComm · doi:10.1002/mco2.70486 · Cited by 1

The impact of STING signaling on myeloid cells highlights macrophages as the major player in controlling Brucella abortus

de Andrade, K. Q., de Queiroz, N. M. G. P., Mambelli, F., Marinho, F. V., Amaral, M. P., Amarante-Mendes, J. G. P., Barber, G. N., & Oliveira, S. C. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1727400 · Cited by 1

TANK-binding Kinase 1 regulates the intracellular survival of Brucella

Li, Z., Wang, S., Li, R., Cui, Y., Zhang, J., Hao, J., Zhang, H., Li, Q., & Zhang, H. (2026) · Veterinary Microbiology · doi:10.1016/j.vetmic.2026.110904 · Cited by 1

Pharmacological inhibition of USP18 improves antibacterial responses and the intracellular control of Mycobacterium tuberculosis in macrophages

Zhang, Q., Gong, Z., Schnell, R., Zhong, Y., Geurink, P. P., Lauschke, V. M., Xie, J., Gastaldello, S., & Rottenberg, M. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1739628 · Cited by 1

The mouse gastric surface epithelial cell and its response to early Helicobacter pylori infection

Erhardsson, M., Santos, L., Benktander, J. D., Sharba, S., Thorell, K., & Lindén, S. K. (2026) · Virulence · doi:10.1080/21505594.2026.2645859 · Cited by 1

Prim-O-glucosylcimifugin ameliorates rheumatoid arthritis by targeting GBP5 to suppress pyroptosis and inhibit synovial cell proliferation

Wang, Y., Guan, W., Wang, S., Bi, Y., Zhang, J., Hao, Z., Liu, Z., Li, M., Liu, S., Chen, Q., et al. (2026) · Biochemical Pharmacology · doi:10.1016/j.bcp.2026.118100 · Cited by 1

Novel coding genetic variants of the GBP1 gene in wild and domestic pigs (Sus scrofa)

Chen, S., Gomes, R., Costa, V., Rocha, I., Zsolnai, A., Anton, I., Charneca, R., Santos, P., Nunes, J. T., Buzgó, J., et al. (2012) · Livestock Science · doi:10.1016/j.livsci.2012.02.008 · Cited by 1

Differentially Expressed Gene Patterns in Ascarid-Infected Chickens of Higher- or Lower-Performing Genotypes

Kilic, I., Stehr, M., Hennies, M., Metges, C. C., Franzenburg, S., Falker‐Gieske, C., Tetens, J., & Daş, G. (2021) · Animals · doi:10.3390/ani11041002 · Cited by 1

GFP Antibody

Vashist, S. (2013) · Materials and Methods · doi:10.13070/mm.en.3.176 · Cited by 1

Guanylate-binding proteins protect the sea cucumbers Apostichopus japonicus against infection of Vibrio splendidus

Yang, L., & Li, C. (2025) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2025.110320 · Cited by 1

Protein/Peptide Tags

Johnson, M. (2012) · Materials and Methods · doi:10.13070/mm.en.2.116 · Cited by 1

Host defenses to intracellular bacteria

Reece, S. T., & Kaufmann, S. H. E. (2013) · Elsevier eBooks · doi:10.1016/b978-0-7234-3691-1.00046-5 · Cited by 1

Tuberculosis

Portal‐Celhay, C., & Philips, J. A. (2019) · Springer eBooks · doi:10.1007/978-1-4939-9034-4_29 · Cited by 1

Aetiopathogenesis, immunology and microbiology of tuberculosis

Barreira‐Silva, P., Torrado, E., Nebenzahl-Guimaraes, H., Källenius, G., & Correia‐Neves, M. (2018) · European Respiratory Society eBooks · doi:10.1183/2312508x.10020917 · Cited by 1

Autophagy Inducing Capacities of a Commercial Preparation Based on of Bacillus thuringiensis Cry1A-Cr2A Autophagy-Inducing Properties Toxins in Human Macrophages: Implication Against Mycobacterial Infections

Andy, R. D., Esmeralda, J., Yolanda, G., Favela-Hernández, J. M., & Gloria, G. G. (2022) · ACTA SCIENTIFIC MICROBIOLOGY · doi:10.31080/asmi.2022.05.1178 · Cited by 1

The Role of Host‐ and Parasite‐Encoded Kinases inToxoplasma–Host Interactions

Blader, I. J., Arrizabalaga, G., & Sullivan, W. J. (2013) · Wiley eBooks · doi:10.1002/9783527675401.ch10 · Cited by 1

Transcriptomic analyses reveal tissue-specific selection on genes related to apoptotic processes in the subterranean rodent, Ctenomys sociabilisPreprint

Lang, A. S., Kordonowy, L. L., Lacey, E. A., & MacManes, M. D. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/256875 · Cited by 2

Comparative gene pathway analysis during adolescent binge-EtOH exposure, withdrawal, and following abstinencePreprint

Nato, A. Q., Mustafa, H. A. U., Sexton, H. G., Moore, S. D., Denvir, J., Primerano, D. A., & Risher, M. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.02.365841 · Cited by 1

Toxoplasma -proximal and distal control by GBPs in human macrophagesPreprint

Fisch, D., Clough, B., Khan, R. T., Healy, L. E., & Frickel, E. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.08.24.457560 · Cited by 1

In vivo reprogramming of murine host immune response genes following Leishmania major infectionPreprint

Venugopal, G., Bird, J. T., Washam, C. L., Roys, H., Bowlin, A. K., Byrum, S. D., & Weinkopff, T. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.05.463063 · Cited by 1

Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2Preprint

Loschwitz, J., Steffens, N., Wang, X., Schäffler, M., Pfeffer, K., Degrandi, D., & Strodel, B. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.27.489784 · Cited by 1

Type-I IFNs induce GBPs and lysosomal defense in hepatocytes to control malariaPreprint

Marques-da-Silva, C., Schmidt-Silva, C., Bowers, C., Charles-Chess, N. A. E., Shiau, J. C., Park, E., Yuan, Z., Kim, B.-H., Kyle, D. E., Harty, J. T., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.22.619707 · Cited by 1

Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophagesPreprint

Egan, M. S., O'Rourke, E. A., Mageswaran, S. K., Zuo, B., Martynyuk, I., Demissie, T., Hunter, E. N., Bass, A. R., Chang, Y., Brodsky, I. E., et al. (2024) · eLife · doi:10.7554/elife.90107.2 · Cited by 2

Exploring the mechanism of kaji-ichigoside F1 on bacterial pneumonia based on the network pharmacology and transcriptomePreprint

Yang, J., Yang, X., Wu, L., & Min, C. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.17.649383 · Cited by 1

Guanylate-Binding Proteins Promote Host Defense Against Leishmania major by Balancing iNOS/Arg-1 in Myeloid CellsPreprint

Fry, L., Adhvaryu, H., Roys, H., Bowlin, A. K., Venugopal, G., Bird, J. T., Washam, C. L., Yamamoto, M., Coers, J., Byrum, S. D., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.26.661809 · Cited by 1

Golgi-localised Guanylate-binding protein 5 enhances glycolysis in macrophagesPreprint

Reyna, S. J. L., Clough, B., Channell, W. M., McCarthy, C., Barlow, J. P., Stanulović, V. S., Hoogenkamp, M., Roberts, J., Marzullo, B. P., Shenoy, A. R., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.17.706357 · Cited by 1

Evasion of interferon-gamma responses by Toxoplasma gondii in murine and human fibroblasts

Niedelman, W. (2013) · DSpace@MIT (Massachusetts Institute of Technology)

Mycobacterium Tuberculosis and the Autophagic Pathway

Recalde, G. M., & Colombo, M. I. (2014) · Wiley eBooks · doi:10.1002/9781118677551.ch14

The Effects of GMS Immunity-Related GTPases on Guanylate-Binding Proteins, Protein

Traver, M. K. (2013)

Identification of host gene expression biomarkers for tuberculosis

Kaforou, M. (2015) · Spiral (Imperial College London) · doi:10.25560/28956

Egress and Limits Parasite Replication gondii Infection Induces Early Parasite Human Fibroblasts upon Toxoplasma Cell Death of Gamma Interferon-Stimulated

Frickel, E., Saeij, J. P. J., Niedelman, W., Sprokholt, J. K., & Clough, B. (2013)

Tags peptidiques/protéiques

Johnson, M. (2012) · Materials and Methods · doi:10.13070/mm.fr.2.116

Putative role for the GTPase, hGBP-1, in tumor cell proliferation and resistance to paclitaxel

Chowdhury, S. (2014) · OhioLink ETD Center (Ohio Library and Information Network)

Souris et Rats de Laboratoire

Johnson, M. (2012) · Materials and Methods · doi:10.13070/mm.fr.2.113

Signaling with the Cytoskeleton Interaction of T Cell Antigen Receptor Mediated − Guanylate Binding Protein 1

Stürzl, M., Elisabeth, H. S., Schmid, J. A., Zlabinger, G. J., Eckerstorfer, P., Britzen‐Laurent, N., Sunzenauer, S., Ostler, N., Paster, W., & Supper, V. (2014)

Macrophage Phagocytosis Abilities Measured with Flow Cytometry Method

Zhang, Y., Zhang, Z., Chen, X., Han, L., & Liu, G. (2014)

Mechanisms by Which Guanylate Binding Proteins Target Pathogen Vacuoles and Promote Caspase-11 Dependent Pyroptosis

Moffett, D. (2015) · DukeSpace (Duke University)

Autophagy and Pattern Recognition Receptors

Viret, C., & Faure, M. (2016) · Springer eBooks · doi:10.1007/978-3-319-30079-5_2

Nucleic Acid Detection in Anti-Viral Responses and Autoimmunity

Brunette, R. L. (2012) · ResearchWorks at the University of Washington (University of Washington)

Activation and Inhibition of Multiple Inflammasome Pathways by the Yersinia Pestis Type Three Secretion System: A Dissertation

Ratner, D. (2016) · eScholarship@UMassChan · doi:10.13028/m21p4v

Trypanosoma cruzi Host Resistance to Response and β Inflammasomes Mediate IL-1 Containing a Caspase Recruitment Domain like Protein - Apoptosis-Associated Speck

Silva, S., Gazzinelli, R. T., Zamboni, D. S., Niz, M. D., Horta, C. V., Silva, G. K., Sesti‐Costa, R., & Nunes, T. A. (2013)

Neuroimmunotoxicology of the heavy metal toxicant lead

Kasten‐Jolly, J., & Lawrence, D. A. (2018) · Advances in neurotoxicology · doi:10.1016/bs.ant.2018.10.004

Immune control of Legionella pneumophila lung infection

Yang, C. (2018) · Minerva Access (University of Melbourne)

Development and Application of Classical Genetics in Toxoplasma gondii

Ajioka, J. W., & Sibley, L. D. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-396481-6.00016-7

Identifying Mechanisms Used by Adherent-invasive Escherichia coli Associated with Crohn Disease to Evade the Immune System

Ossa, J. C. (2012) · TSpace (University of Toronto)

Cell-based assays to assess the immunostimulatory capacity of poultry vaccines

van den Biggelaar, R. H. G. A. (2021) · Utrecht University Repository (Utrecht University) · doi:10.33540/433

Analyzing factors involved in genetic variation of porcine response to Salmonella

Uthe, J. J. (2012) · doi:10.31274/etd-180810-1139

Cell-Autonomous Defenses Against Intracellular Bacteria and Protozoa

Brož, P. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821618-7.00044-4

Antiviral Responses

Elbim, C., & Appay, V. (2016) · Compendium of Inflammatory Diseases · doi:10.1007/978-3-7643-8550-7_81

Antiviral Responses

Elbim, C., & Appay, V. (2013) · Encyclopedia of Inflammatory Diseases · doi:10.1007/978-3-0348-0620-6_81-2

蛋白/肽标签

Johnson, M. (2012) · 实验材料和方法 · doi:10.13070/mm.cn.2.116

Faculty Opinions recommendation of Lipid droplet formation in Mycobacterium tuberculosis infected macrophages requires IFN-γ/HIF-1α signaling and supports host defense.

Kana, B. D. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.732567842.793546284

实验室小鼠和大鼠

Johnson, M. (2012) · 实验材料和方法 · doi:10.13070/mm.cn.2.113

The Sculpting of theMycobacterium tuberculosisGenome by Host Cell-Derived Pressures

Russell, D. G., Lee, W., Tan, S., Sukumar, N., Podinovskaia, M., Fahey, R. J., & VanderVen, B. C. (2015) · ASM Press eBooks · doi:10.1128/9781555818845.ch35

Guanylate binding protein 2b contributes to M1 macrophage polarization during Mycobacterium bovis infectionPreprint

Yu, Y., Liu, M., Pan, J., Tao, L., Xue, F., Tang, F., Wang, H., Dai, J., & Shan, Y. (2022) · Research Square · doi:10.21203/rs.3.rs-1631961/v1

Regulation of neutrophil NETosis by inflammasome

Hogg, A. J., Barlow, J. L., & Boucher, D. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91802-2.00036-0

Lactoferrin feeding deficiency during lactation increases the risk of depression in adult mice by affecting microbiota-gut-brain axis developmentPreprint

Wang, W., Cheng, Z., Wang, X., Qin, A., Huang, K., Dai, Y., Meng, Q., & Zhang, Y. (2022) · Research Square · doi:10.21203/rs.3.rs-1883790/v2

IL-12/IFN-γ axis drives skin wound healing via innate defense mechanisms against bacterial invasion in teleost fishPreprint

Qiu, X., Yang, M., Sun, H., Liu, J., Wang, X., Zhang, A., YANG, K. Y., & Zhou, H. Y. (2023) · Research Square · doi:10.21203/rs.3.rs-3360588/v1

Developmental Stage and Cellular Context Determine Oncogenic and Molecular Outcomes of Ezh2 Y641F Mutation in HematopoiesisPreprint

Zimmerman, S. M., Procasky, S. J., Smith, S. R., Liu, J., Torrice, C., & Souroullas, G. P. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.14.622807

SYSTEMS AND NETWORK BIOLOGY ANALYSIS COMBINED WITH MACHINE LEARNING IDENTIFIES KEY IMMUNE RESPONSE PROFILES AND POTENTIAL CORRELATES OF PROTECTION FOR THE M72/AS01E TUBERCULOSIS VACCINEPreprint

Taofeek, O. O., Alile, S. O., Elcanah, E. M., Ezediuno, L. O., George, I. A., Oyewole, O. M., Owiti, P., & Sulaimon, L. A. (2025) · medRxiv · doi:10.1101/2025.01.13.25320455

GBP1 drives lysosomal activity against cytosol-invading mycobacteria in macrophagesPreprint

Aguirre-García, M. A., Portelli, S. M., Varela, M., & Meijer, A. H. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.28.650982 · Cited by 1

Deletion of Murine Endothelial Bag3 Alters the Cellular Proteome among Organs of Origin

Terwilliger, Z. S., Li, F., Pentakota, A., Zeczycki, T. N., Green, T. D., Kolasa, M., Edwards, N. C., Goldman, M. P., Fisher‐Wellman, K. H., & McClung, J. M. (2026) · Journal of Vascular Research · doi:10.1159/000552442

GBP1 recruitment to actin-rich pedestals induced by extracellular Gram-negative bacteria promotes pyroptosisPreprint

Bennison, D. J., Chaudhary, I., Chaudhuri, D., Wong, J. C. N., Punwatkar, A., Biswas, P., Stephenson, M., Zhong, Q., Kallemeijn, W. W., Guenot, M., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.25.678451

Ben_0691 functions as an IRG-47 mycoplasma stimulator that mediates host cell resistance to Mycoplasma mycoides subsp. mycoides infection

Liu, T., Zhao, H., Wang, X., Xu, Q., Li, Y., Wu, Q., Wei, Y., Xin, J., & Pan, Q. (2025) · Communications Biology · doi:10.1038/s42003-025-08950-8

Examination of the Antibacterial and Immunostimulatory Activity of a Wasp Venom Peptide

Mobley, Y. R. (2013)

Additional file 3 of Markers of immune dysregulation in response to the ageing gut: insights from aged murine gut microbiota transplants

Giannos, P., Prokopidis, K., Isanejad, M., & Wright, H. L. (2023) · Figshare · doi:10.6084/m9.figshare.22609202

Additional file 2 of Markers of immune dysregulation in response to the ageing gut: insights from aged murine gut microbiota transplants

Giannos, P., Prokopidis, K., Isanejad, M., & Wright, H. L. (2023) · Figshare · doi:10.6084/m9.figshare.22609199

The Effects of GMS Immunity-Related GTPases on Guanylate-Binding Proteins, Protein Aggregate Formation, and Macroautophagy

Traver, M. K. (2013) · DukeSpace (Duke University)

Additional file 1 of Lactoferrin deficiency during lactation increases the risk of depressive-like behavior in adult mice

Wang, W., Cheng, Z., Wang, X., An, Q., Huang, K., Dai, Y., Meng, Q., & Zhang, Y. (2023) · Figshare · doi:10.6084/m9.figshare.24472477

Additional file 1 of Clearance of bacteria from lymph nodes in sheep immunized with Brucella suis S2 vaccine is associated with M1 macrophage activation

Chen, S., Chen, Y., Jiao, Z., Wang, C., Zhao, D., Liu, Y., Zhang, W., Zhao, S., Yang, B., Zhao, Q., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26575196

IFN-γ and IL-6 as Key Predicting Biomarkers for Active TB Among PLWH: Results from Four Machine Learning Methods

Wan, J., Chongsuvivatwong, V., Zhang, P., Li, Q., Zhao, L., Zou, L., Zhao, J., & Dai, J. (2026) · International Journal of General Medicine · doi:10.2147/ijgm.s572335 · Cited by 1

Guanylate-binding proteins balance iNOS/Arg-1 in myeloid cells during L. major infection and promote host defense to infection

Fry, L., Adhvaryu, H., Roys, H., Bowlin, A. K., Venugopal, G., Bird, J. T., Washam, C. L., Yamamoto, M., Coers, J., Byrum, S., et al. (2026) · mBio · doi:10.1128/mbio.02825-25 · Cited by 1

Host genetic ancestry and immunity to pathogens

Castanha, P. M. S., Martí, M. M., Marques, E. T., Martinson, J. J., & Barratt‐Boyes, S. M. (2026) · Trends in Microbiology · doi:10.1016/j.tim.2026.02.007

Le rôle des Guanylate Binding Proteins dans l’immunité cytosolique du macrophage : bactériolyse et morts cellulaires inflammasome-dépendant et indépendant

Wallet, P. (2017) · theses.fr (ABES) · doi:10.70675/81efce18ze9faz40cfzab53z6bfc2b336690

Efficacité antivirale des différents types d'interférons sur la multiplication du virus BK

Martin, É. (2017) · theses.fr (ABES) · doi:10.70675/f80cce06z65f6z437ez9dd1z73273b4ba3a4

Modulation de l'autophagie des macrophages : rôle des lipides de l'enveloppe

Bah, A. (2017) · theses.fr (ABES) · doi:10.70675/0170380fz0af5z4c02za7aezd5ac5153ffd8

Detection of cytosolic LPS : a genome-wide CRISPR/Cas9 screen identifies IRF2 as a regulator of the non-canonical inflammasome caspase-4

Benaoudia, S. (2018) · theses.fr (ABES) · doi:10.70675/88572e41za0f2z46b3zbaecz6d4664253112

Primary infection with Cystoisospora suis modulates systemic immunity and the gut microbiota during secondary infection in piglets

Ye, X., Huang, Y.-J., Deng, X.-L., He, Z.-Y., Tan, J.-J., Lu, X., He, X., Wang, X.-Q., Weng, Y., Tan, Z.-J., et al. (2026) · International Journal for Parasitology · doi:10.1016/j.ijpara.2026.104847

Human inherited IRF1 deficiency

Rosain, J. (2022) · theses.fr (ABES) · doi:10.70675/067993b6zab73z45fazb9aez6af7872f8ba2

Dissecting human population variation in single-cell responses to SARS-CoV-2

Aquino, Y. (2023) · theses.fr (ABES) · doi:10.70675/061da45czf5e5z482dzb71dz92b95c997a05

Aberrant expression of GBP5 in tumor-infiltrating immune cells as an onco-immunological biomarker in pan-cancer

Liu, R., Gong, J., Zhang, Y., Chen, Q., Han, T., Li, W., Zhang, H., & Li, Y. (2026) · Discover Oncology · doi:10.1007/s12672-026-05305-5

Material‐Encoded Synchronization of Immunogenic Cell Death With Adenosine A2A Receptor Blockade Reprograms the Tumor Microenvironment

Yi, X., Yang, H., Huang, J. F., Wu, P., Zhou, S., Liao, Z., Han, M., Chen, Z., Huang, X., Ma, N., et al. (2026) · Advanced Science · doi:10.1002/advs.76303

Human GBP4 promotes TRIM21-BIP-dependent autophagy to restrict M. tuberculosis infection by preventing SORT1-mediated progranulin degradation

Guo, Q., Bi, J., Fu, Y., Song, 吕. L., Wu, H., Chen, X., Gong, Y., Feng, C. G., & Zhang, G. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117739

GBP6 maintains mitochondrial bioenergetics to promote immune evasion from NK cells in cervical cancer

Qian, L., Li, Y., Zheng, J., Liang, T., Zhao, R., Wang, X., Liu, X., Liu, X., Song, X., Zhu, M., et al. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117704

When folding CARDs wins the game: molecular snapshots of lipopolysaccharide sensing by the non-canonical inflammasome

Began, J., & Brož, P. (2026) · Biochemical Society Transactions · doi:10.1042/bst20260715

State-selective nanobodies to probe Guanylate-binding protein coat assembly and functionPreprint

Pagani, L. L., Kuhm, T., Pinto, C. D. A., Perton, E. G., Arents, M., Nguyen, P. N. M., Steyaert, J., Pardon, E., & Jakobi, A. J. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.30.755308

GTPase GBP7 promotes HSV-1 infection by interacting with and activating eEF1A1 to accelerate the protein translation process

Wang, J., Man, L., Rong, B., Lu, K., 程露平, He, J., Li, H., Su, H., Lin, X., Li, R., et al. (2026) · PLoS Pathogens · doi:10.1371/journal.ppat.1014652

This Week in Science

(2011) · Science · doi:10.1126/science.2011.332.6030.twis

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

Yamamoto, M., Okuyama, M., Su, J., Kimura, T., Kamiyama, N., Saiga, H., Ohshima, J., Sasai, M., Kayama, H., Okamoto, T., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.06.009 · Cited by 334

Extensive Characterization of IFN-Induced GTPases mGBP1 to mGBP10 Involved in Host Defense

Degrandi, D., Konermann, C., Beuter-Gunia, C., Kresse, A., Wuerthner, J., Kurig, S., Beer, S., & Pfeffer, K. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.11.7729 · Cited by 209

ID: 165

Pfeffer, K., Degrandi, D., & Kravets, E. (2015) · Cytokine · doi:10.1016/j.cyto.2015.08.036

IFN-Inducible GTPases in Host Cell Defense

Kim, B.-H., Shenoy, A. R., Kumar, P., Bradfield, C. J., & MacMicking, J. D. (2012) · Cell Host & Microbe · doi:10.1016/j.chom.2012.09.007 · Cited by 287