The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Synthesis of Methylphosphonic Acid by Marine Microbes: A Source for Methane in the Aerobic Ocean
Open accessAbstract
Ocean Methane: Is methylphosphonate a natural product? If it is, then its catabolism by microrganisms seeking phosphorus might explain the ubiquity of methane in the oceans. Anaerobic Archaea, so far, are the only significant source of methane known. Thus, Metcalf et al. (p. 1104 ) looked for evidence of methylphosphonate biochemistry in the widespread archaeon Nitrosopumilus maritimus. The organism can synthesize C-P bonds using phosphoenolpyruvate mutase. By using its gene, ppm , as a marker, a possible phosphonate biosynthesis gene cluster was identified, and adjacent to this a gene for a cupin was found. Together with Fe(II) and O 2 the cupin catalyzed the production of methylphosphonate and formate. Homologs of the cupin gene are found in a wide range of common marine microbes, including Pelagibacter ubique and Prochlorococcus.
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Cites
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models
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Isolation of an autotrophic ammonia-oxidizing marine archaeon
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Self-citationAmmonia oxidation kinetics determine niche separation of nitrifying Archaea and Bacteria
Martens-Habbena, W., Berube, P. M., Urakawa, H., de la Torre, J. R., & Stahl, D. A. (2009) · Nature · doi:10.1038/nature08465 · Cited by 1,651
Self-citationArchaeal dominance in the mesopelagic zone of the Pacific Ocean
Karner, M. B., DeLong, E. F., & Karl, D. M. (2001) · Nature · doi:10.1038/35054051 · Cited by 1,592
Oceanic Methane Biogeochemistry
Reeburgh, W. S. (2007) · Chemical Reviews · doi:10.1021/cr050362v · Cited by 1,575
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Cited by
Santoro, A. E., Dupont, C. L., Richter, R. A., Craig, M. T., Carini, P., McIlvin, M. R., Yang, Y., Orsi, W. D., Moran, D. M., & Saito, M. A. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1416223112 · Cited by 268
Phosphonate production by marine microbes: exploring new sources and potential function
Acker, M., Hogle, S. L., Berube, P. M., Hackl, T., Coe, A., Stepanauskas, R., Chisholm, S. W., & Repeta, D. J. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2113386119 · Cited by 76
Schwander, L., Brabender, M., Mrnjavac, N., Wimmer, J. L. E., Preiner, M., & Martin, W. F. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1257597 · Cited by 65
“Their exact function is still not known, but they might represent a means of sequestering phosphorus among community members (Metcalf et al., 2012).”
Background
Metadata
- Authors
- Metcalf, W. W., Griffin, B. M., Cicchillo, R. M., Gao, J., Janga, S. C., Cooke, H. A., Circello, B. T., Evans, B. S., Martens-Habbena, W., Stahl, D. A., & van der Donk, W. A.
- Venue
- Science
- Published
- 2012-08-31
- Volume
- 337
- Issue
- 6098
- Pages
- 1104-1107
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2008421066
- Cited by
- 314
- References
- 27
- FWCI
- 18.34
- Type
- journal article
- Language
- en
- Open access
- green
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- Metcalf, W. W., Griffin, B. M., Cicchillo, R. M., Gao, J., Janga, S. C., Cooke, H. A., Circello, B. T., Evans, B. S., Martens-Habbena, W., Stahl, D. A., & van der Donk, W. A. (2012). Synthesis of Methylphosphonic Acid by Marine Microbes: A Source for Methane in the Aerobic Ocean. Science. https://doi.org/10.1126/science.1219875
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