The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Rapid Folding of DNA into Nanoscale Shapes at Constant Temperature
Abstract
Speeding Up Nanoscale DNA Assembly: An impressive array of three-dimensional (3D) nanoscale objects has been assembled by folding a long, single-stranded DNA scaffold by binding of short DNA staples. However, these processes tend to be slow and inefficient. Sobczak et al. (p. 1458 ) examined the folding process with an intercalating fluorescence dye to measure the formation of double-stranded DNA in folding processes or single-stranded DNA in unfolding. Reaction conditions were identified that sped up folding by orders of magnitude and increased yields of the 3D nanoscale objects to nearly 100%.
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“Because of the noncovalent nature of DNA nanostructures, they can be reconfigured using established strategies, including strand displacement,26 thermal annealing,105 and pH changes.106”
From Emerging Approaches to DNA Data Storage: Challenges and Prospects (2022) · cites this paper as [105]
Citations
Cites
Folding DNA to create nanoscale shapes and patterns
Rothemund, P. W. K. (2006) · Nature · doi:10.1038/nature04586 · Cited by 7,474
Self-assembly of DNA into nanoscale three-dimensional shapes
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Self-citationA Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads
Douglas, S. M., Bachelet, I., & Church, G. M. (2012) · Science · doi:10.1126/science.1214081 · Cited by 2,187
Self-assembly of a nanoscale DNA box with a controllable lid
Andersen, E. S., Dong, M., Nielsen, M. M., Jahn, K., Subramani, R., Mamdouh, W., Golas, M. M., Sander, B. O., Stark, H., Oliveira, C. L. P., et al. (2009) · Nature · doi:10.1038/nature07971 · Cited by 1,650
Folding DNA into Twisted and Curved Nanoscale Shapes
Dietz, H., Douglas, S. M., & Shih, W. M. (2009) · Science · doi:10.1126/science.1174251 · Cited by 1,361
Self-citationChallenges and opportunities for structural DNA nanotechnology
Pinheiro, A. V., Han, D., Shih, W. M., & Yan, H. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.187 · Cited by 1,292
Rapid prototyping of 3D DNA-origami shapes with caDNAno
Douglas, S. M., Marblestone, A. H., Teerapittayanon, S., Vazquez, A., Church, G. M., & Shih, W. M. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp436 · Cited by 1,244
DNA Origami with Complex Curvatures in Three-Dimensional Space
Han, D., Pal, S., Nangreave, J., Deng, Z., Liu, Y., & Yan, H. (2011) · Science · doi:10.1126/science.1202998 · Cited by 1,243
Complex shapes self-assembled from single-stranded DNA tiles
Wei, B., Dai, M., & Yin, P. (2012) · Nature · doi:10.1038/nature11075 · Cited by 1,012
From molecular to macroscopic via the rational design of a self-assembled 3D DNA crystal
Zheng, J., Birktoft, J. J., Chen, Y., Wang, T., Sha, R., Constantinou, P. E., Ginell, S. L., Mao, C., & Seeman, N. C. (2009) · Nature · doi:10.1038/nature08274 · Cited by 1,003
Cited by
Sorted by citations
Programmable materials and the nature of the DNA bond
Jones, M. R., Seeman, N. C., & Mirkin, C. A. (2015) · Science · doi:10.1126/science.1260901 · Cited by 1,347
DNA Origami: Scaffolds for Creating Higher Order Structures
Fan, H. B., Zhang, F., Liu, Y., & Yan, H. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00825 · Cited by 1,108
Super-resolution microscopy with DNA-PAINT
Schnitzbauer, J., Strauss, M. T., Schlichthaerle, T., Schueder, F., & Jungmann, R. (2017) · Nature Protocols · doi:10.1038/nprot.2017.024 · Cited by 1,047
Dey, S., Fan, C., Gothelf, K. V., Li, J., Lin, C., Liu, L., Liu, N., Nijenhuis, M. A. D., Saccà, B., Simmel, F. C., et al. (2021) · Nature Reviews Methods Primers · doi:10.1038/s43586-020-00009-8 · Cited by 815
Dynamic DNA devices and assemblies formed by shape-complementary, non–base pairing 3D components
Gerling, T., Wagenbauer, K. F., Neuner, A. M., & Dietz, H. (2015) · Science · doi:10.1126/science.aaa5372 · Cited by 659
Self-citation
Metadata
- Authors
- Sobczak, J.-P. J., Martin, T. G., Gerling, T., & Dietz, H.
- Affiliations
- Technical University of Munich (DE)
- Corresponding author
- Dietz, Hendrik
- Venue
- Science
- Published
- 2012-12-14
- Volume
- 338
- Issue
- 6113
- Pages
- 1458-1461
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2049040320
- Cited by
- 285
- References
- 29
- Citations by year
- 2026: 9 · 2025: 13 · 2024: 17 · 2023: 18 · 2022: 18 · 2021: 13 · 2020: 15 · 2019: 20 · 2018: 25 · 2017: 24 · 2016: 28 · 2015: 26 · 2014: 42 · 2013: 15 · 2012: 2
- FWCI
- 10.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Advanced biosensing and bioanalysis techniques
- Physical Sciences › Mathematics › Theoretical Computer Science › DNA and Biological Computing
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Nucleic Acid Chemistry
- Keywords
- DNA folding, DNA nanotechnology, cooperative folding, nucleation, DNA origami, folding kinetics, DNA topology
- MeSH terms
- DNA, Nucleic Acid Conformation, Temperature, Templates, Genetic, Protein Folding, Nanotechnology, Nanostructures
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