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Cited by 967

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells

Open access
Nieto, M. Angela·2013·Science

Abstract

From Here to There: To form different tissues and organs, embryonic cells must migrate to new locations. Specific transcription factors, epigenetic and splicing programs, and microRNA regulatory networks regulate this process, which is known as the epithelial-to-mesenchymal transition (EMT). During EMT, considerable cellular plasticity is observed, and once activated at their new location, cells must again change into their new differentiated form. This “reverse” event is called the mesenchymal-to-epithelial transition (MET). Nieto (p. 10.1126/science.1234850 ) reviews EMT and MET as observed during normal development and in the generation of cancer when cells leave the primary tumor and travel to other parts of the body forming metastases and secondary tumors.

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Metadata

Authors
Nieto, M. A.
Venue
Science
Published
2013-11-08
Volume
342
Issue
6159
Pages
1234850-1234850
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2164358503
Cited by
967
References
6
FWCI
45.22
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells. https://app.cochat.ai/papers/10.1126/science.1234850
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Nieto, M. A. (2013). Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells. Science. https://doi.org/10.1126/science.1234850

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.