The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
Open accessAbstract
From Here to There: To form different tissues and organs, embryonic cells must migrate to new locations. Specific transcription factors, epigenetic and splicing programs, and microRNA regulatory networks regulate this process, which is known as the epithelial-to-mesenchymal transition (EMT). During EMT, considerable cellular plasticity is observed, and once activated at their new location, cells must again change into their new differentiated form. This “reverse” event is called the mesenchymal-to-epithelial transition (MET). Nieto (p. 10.1126/science.1234850 ) reviews EMT and MET as observed during normal development and in the generation of cancer when cells leave the primary tumor and travel to other parts of the body forming metastases and secondary tumors.
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Cites
The basics of epithelial-mesenchymal transition
Kalluri, R., & Weinberg, R. A. (2009) · Journal of Clinical Investigation · doi:10.1172/jci39104 · Cited by 10,196
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Polyak, K., & Weinberg, R. A. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2620 · Cited by 3,302
Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
Peinado, H., Olmeda, D., & Cano, A. (2007) · Nature reviews. Cancer · doi:10.1038/nrc2131 · Cited by 3,121
Regulatory networks defining EMT during cancer initiation and progression
Craene, B. D., & Berx, G. (2013) · Nature Reviews Cancer · doi:10.1038/nrc3447 · Cited by 2,487
A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells
Polo, J. M., Anderssen, E., Walsh, R. M., Schwarz, B. A., Nefzger, C. M., Lim, S. M., Borkent, M., Apostolou, E., Alaei, S., Cloutier, J., et al. (2012) · Cell · doi:10.1016/j.cell.2012.11.039 · Cited by 861
Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest
Rada-Iglesias, A., Bajpai, R., Prescott, S., Brugmann, S. A., Swigut, T., & Wysocka, J. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.07.006 · Cited by 314
Cited by
Nieto, M. A., Huang, R. Y.-J., Jackson, R. A., & Thiery, J. P. (2016) · Cell · doi:10.1016/j.cell.2016.06.028 · Cited by 4,492
Self-citationSignaling mechanisms of the epithelial-mesenchymal transition
Gonzalez, D. M., & Medici, D. (2014) · Science Signaling · doi:10.1126/scisignal.2005189 · Cited by 1,721
Epithelial Mesenchymal Transition in Tumor Metastasis
Mittal, V. (2018) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-020117-043854 · Cited by 1,528
Zhang, J., Tian, X.-J., Zhang, H., Teng, Y., Li, R., Bai, F., Elankumaran, S., & Xing, J. (2014) · Science Signaling · doi:10.1126/scisignal.2005304 · Cited by 462
Cellular plasticity and the neuroendocrine phenotype in prostate cancer
Davies, A. H., Beltran, H., & Zoubeidi, A. (2018) · Nature Reviews Urology · doi:10.1038/nrurol.2018.22 · Cited by 431
Metadata
- Authors
- Nieto, M. A.
- Venue
- Science
- Published
- 2013-11-08
- Volume
- 342
- Issue
- 6159
- Pages
- 1234850-1234850
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2164358503
- Cited by
- 967
- References
- 6
- FWCI
- 45.22
- Type
- journal article
- Language
- en
- Open access
- green
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