A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

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Functions of DNA methylation: islands, start sites, gene bodies and beyond

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

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Summaries of Affymetrix GeneChip probe level data

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More powerful procedures for multiple significance testing

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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

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Dissecting direct reprogramming through integrative genomic analysis

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Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

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An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

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A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

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Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming.

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Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells.

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Induced pluripotency: history, mechanisms, and applicationsPreprint

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Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse

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Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

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Role of the murine reprogramming factors in the induction of pluripotency

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Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette

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Elite and stochastic models for induced pluripotent stem cell generation

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Harnessing the potential of induced pluripotent stem cells for regenerative medicine

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Chromatin Connections to Pluripotency and Cellular Reprogramming

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Reprogramming Factor Expression Initiates Widespread Targeted Chromatin Remodeling

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The Transcription Factor T-bet Is Induced by Multiple Pathways and Prevents an Endogenous Th2 Cell Program during Th1 Cell Responses

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Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells

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Regulation of Pluripotency and Cellular Reprogramming by the Ubiquitin-Proteasome System

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A reprogrammable mouse strain from gene targeted embryonic stem cells

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Highly Coordinated Proteome Dynamics during Reprogramming of Somatic Cells to Pluripotency

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Dynamic single-cell imaging of direct reprogramming reveals an early specifying event

Smith, Z. D., Nachman, I., Regev, A., & Meissner, A. (2010) · Nature Biotechnology · doi:10.1038/nbt.1632 · Cited by 205 · see citing works

BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone

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Fast network component analysis (FastNCA) for gene regulatory network reconstruction from microarray data

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Normal Embryonic and Germ Cell Development in Mice Lacking α1,3-Fucosyltransferase IX (Fut9) Which Show Disappearance of Stage-Specific Embryonic Antigen 1

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From microRNAs to targets: pathway discovery in cell fate transitions

Subramanyam, D., & Blelloch, R. H. (2011) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2011.04.011 · Cited by 68 · see citing works

Discovery of Nonsteroidal Anti-Inflammatory Drug and Anticancer Drug Enhancing Reprogramming and Induced Pluripotent Stem Cell Generation

Yang, C., López, C. G., & Rana, T. M. (2011) · Stem Cells · doi:10.1002/stem.717 · Cited by 53 · see citing works

Genome-Wide Determination of DNA Methylation by Hpa II Tiny Fragment Enrichment by Ligation-Mediated PCR (HELP) for the Study of Acute Leukemias

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Pivots of pluripotency: The roles of non-coding RNA in regulating embryonic and induced pluripotent stem cells

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Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yin, Y., Morgunova, E., Jolma, A., Kaasinen, E., Sahu, B., Khund-Sayeed, S., Das, P. K., Kivioja, T., Dave, K., Zhong, F., et al. (2017) · Science · doi:10.1126/science.aaj2239 · Cited by 1,257 · see citing works

Visualizing structure and transitions in high-dimensional biological data

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In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.

Ocampo, A., Reddy, P., Martinez-Redondo, P., Platero-Luengo, A., Hatanaka, F., Hishida, T., Li, M., Lam, D., Kurita, M., Beyret, E., et al. (2016) · Cell · doi:10.1016/j.cell.2016.11.052 · Cited by 988 · see citing works

Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells

Nieto, M. A. (2013) · Science · doi:10.1126/science.1234850 · Cited by 962 · see citing works

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

Schiebinger, G., Shu, J., Tabaka, M., Cleary, B., Subramanian, V., Solomon, A., Gould, J., Liu, S., Lin, S., Berube, P., et al. (2019) · Cell · doi:10.1016/j.cell.2019.01.006 · Cited by 829 · see citing works

A decade of transcription factor-mediated reprogramming to pluripotency

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mRNA-based therapeutics: powerful and versatile tools to combat diseases

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Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

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Cooperative Binding of Transcription Factors Orchestrates Reprogramming

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Müller glial cell reprogramming and retina regeneration

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Krüppel-like factor 4 (KLF4): What we currently know

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H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes

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Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation

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Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues

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The RNA-binding protein repertoire of embryonic stem cells

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Mechanisms and models of somatic cell reprogramming

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Citrullination regulates pluripotency and histone H1 binding to chromatin

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Single-cell mapping of lineage and identity in direct reprogramming

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Chromatin dynamics during cellular reprogramming

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SOX2 in development and cancer biology

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Genetic and Epigenetic Variations in iPSCs: Potential Causes and Implications for Application

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Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development

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Replacement of Oct4 by Tet1 during iPSC Induction Reveals an Important Role of DNA Methylation and Hydroxymethylation in Reprogramming

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Metabolic Reprogramming of Stem Cell Epigenetics

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Tet and TDG Mediate DNA Demethylation Essential for Mesenchymal-to-Epithelial Transition in Somatic Cell Reprogramming

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Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade

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Epigenetics of Reprogramming to Induced Pluripotency

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Genetic Background Drives Transcriptional Variation in Human Induced Pluripotent Stem Cells

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Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience

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Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers

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Mesenchymal–epithelial transition in development and reprogramming

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LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells

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Epigenetic changes during aging and their reprogramming potential

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A predictive computational framework for direct reprogramming between human cell types

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Research and therapy with induced pluripotent stem cells (iPSCs): social, legal, and ethical considerations

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Translation of Human-Induced Pluripotent Stem Cells

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The Developmental Control of Transposable Elements and the Evolution of Higher Species

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The histone chaperone CAF-1 safeguards somatic cell identity

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Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming

Prieto, J., León, M., Ponsoda, X., Sendra, R., Bort, R., Ferrer‐Lorente, R., Raya, Á., López‐García, C., & Torres, J. (2016) · Nature Communications · doi:10.1038/ncomms11124 · Cited by 275 · see citing works

Defined three-dimensional microenvironments boost induction of pluripotency

Caiazzo, M., Okawa, Y., Ranga, A., Piersigilli, A., Tabata, Y., & Lutolf, M. P. (2016) · Nature Materials · doi:10.1038/nmat4536 · Cited by 271 · see citing works

A Comparative View on Human Somatic Cell Sources for iPSC Generation

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A XEN-like State Bridges Somatic Cells to Pluripotency during Chemical Reprogramming.

Zhao, Y., Zhao, T., Guan, J.-Y., Zhang, X., Fu, Y., Ye, J., Zhu, J., Meng, G., Ge, J., Yang, S., et al. (2015) · Cell · doi:10.1016/j.cell.2015.11.017 · Cited by 249 · see citing works

HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1–3 and PKM2

Prigione, A., Rohwer, N., Hoffmann, S., Mlody, B., Drews, K., Bukowiecki, R., Blümlein, K., Wanker, E. E., Ralser, M., Cramer, T., et al. (2013) · Stem Cells · doi:10.1002/stem.1552 · Cited by 252 · see citing works

Chromatin Accessibility Dynamics during iPSC Reprogramming

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Highly Coordinated Proteome Dynamics during Reprogramming of Somatic Cells to Pluripotency

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Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate

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Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency

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Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

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Influence of donor age on induced pluripotent stem cells

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Genome-wide Chromatin Interactions of the Nanog Locus in Pluripotency, Differentiation, and Reprogramming

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Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte

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