The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Widespread Production of Extracellular Superoxide by Heterotrophic Bacteria
Abstract
Sending Out an ROS: The global imprint of biological activity in aquatic environments is often considered a consequence of enzyme-mediated redox reactions that support metabolic activity, such as reducing oxygen during respiration. But some organisms also release redox-active reactive oxygen species (ROS) into the environment—to acquire trace metals or to prevent viral infections—which can influence global processes like nutrient availability and contaminant transport. Photosynthetic organisms like phytoplankton are thought to be the primary biological source of ROS in freshwater and marine environments. However, Diaz et al. (p. 1223 , published online 2 May; see the Perspective by Shaked and Rose ) now show that a broad range of ecologically and phylogenetically diverse heterotrophic bacteria also produce large quantities of superoxide. Production rates vary widely across 30 common bacterial isolates but in some cases were greater than production rates of phytoplankton. Because these bacteria do not require light to grow, they may be the dominant source of ROS in dark environments like the deep ocean, terrestrial soils, or lake sediments.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302
Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation
Letunic, I., & Bork, P. (2007) · Bioinformatics · doi:10.1093/bioinformatics/btl529 · Cited by 3,299
Reactivity of HO2/O− 2 radicals in aqueous solution
Bielski, B. H. J., Cabelli, D. E., Arudi, R. L., & Ross, A. B. (1985) · Journal of Physical and Chemical Reference Data · doi:10.1063/1.555739 · Cited by 2,169
Fridovich, I. (1975) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.44.070175.001051 · Cited by 1,730
Interactive Tree Of Life v2: online annotation and display of phylogenetic trees made easy
Letunic, I., & Bork, P. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr201 · Cited by 1,457
Overview of the Marine Roseobacter Lineage
Buchan, A., González, J. M., & Moran, M. A. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.10.5665-5677.2005 · Cited by 844
Microbial Ecology of the Dark Ocean above, at, and below the Seafloor
Orcutt, B. N., Sylvan, J. B., Knab, N. J., & Edwards, K. J. (2011) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00039-10 · Cited by 661
Extracellular superoxide dismutase in biology and medicine
Fattman, C. L., Schaefer, L. M., & Oury, T. D. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(03)00275-2 · Cited by 651
Revisiting Carbon Flux Through the Ocean's Twilight Zone
Buesseler, K. O., Lamborg, C. H., Boyd, P. W., Lam, P. J., Trull, T. W., Bidigare, R. R., Bishop, J. K. B., Casciotti, K. L., Dehairs, F., Elskens, M., et al. (2007) · Science · doi:10.1126/science.1137959 · Cited by 642
Reduction of nitro blue tetrazolium by CO2- and O2- radicals
Bielski, B. H. J., Shiue, G. G., & Bajuk, S. (1980) · The Journal of Physical Chemistry · doi:10.1021/j100445a006 · Cited by 461
Assay of metabolic superoxide production in Escherichia coli.
Imlay, J. A., & Fridovich, I. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)89596-9 · Cited by 420
Formation of manganese oxides by bacterially generated superoxide
Learman, D. R., Voelker, B. M., Vazquez-Rodriguez, A. I., & Hansel, C. M. (2011) · Nature Geoscience · doi:10.1038/ngeo1055 · Cited by 397
Self-citationNOX family NADPH oxidases: Not just in mammals
BEDARD, K., LARDY, B., & KRAUSE, K. (2007) · Biochimie · doi:10.1016/j.biochi.2007.01.012 · Cited by 322
Morris, J. J., Kirkegaard, R., Szul, M. J., Johnson, Z. I., & Zinser, E. R. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.02479-07 · Cited by 298
Manganese oxidation by Leptothrix discophora
Boogerd, F. C., & de Vrind, J. P. (1987) · Journal of Bacteriology · doi:10.1128/jb.169.2.489-494.1987 · Cited by 251
Sunlight-Induced Photochemistry of Humic Substances in Natural Waters: Major Reactive Species
Cooper, W. J., Zika, R. G., Petasne, R. G., & Fischer, A. M. (1988) · Advances in Chemistry · doi:10.1021/ba-1988-0219.ch022 · Cited by 249
Huycke, M. M., Moore, D., Joyce, W., Wise, P., Shepard, L., Kotake, Y., & Gilmore, M. S. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02638.x · Cited by 209
Sunlight and Iron(III)-Induced Photochemical Production of Dissolved Gaseous Mercury in Freshwater
Zhang, H., & Lindberg, S. E. (2001) · Environmental Science & Technology · doi:10.1021/es001521p · Cited by 189
Chen, C., Amirbahman, A., Fisher, N., Harding, G., Lamborg, C., Nacci, D., & Taylor, D. (2008) · EcoHealth · doi:10.1007/s10393-008-0201-1 · Cited by 189
Microbial Reduction and Oxidation of Mercury in Freshwater Lakes
Siciliano, S. D., O'Driscoll, N. J., & Lean, D. R. S. (2002) · Environmental Science & Technology · doi:10.1021/es010774v · Cited by 186
Detection and Quantification of Superoxide Formed within the Periplasm of Escherichia coli
Korshunov, S., & Imlay, J. A. (2006) · Journal of Bacteriology · doi:10.1128/jb.00554-06 · Cited by 182
Generation of Reactive Oxygen Species by Raphidophycean Phytoplankton
Oda, T., Nakamura, A., Shikayama, M., Kawano, I., Ishimatsu, A., & Muramatsu, T. (1997) · Bioscience, Biotechnology, and Biochemistry · doi:10.1271/bbb.61.1658 · Cited by 169
Superoxide production by marine microalgae: I. Survey of 37 species from 6 classes
Marshall, J.-A., de Salas, M., Oda, T., & Hallegraeff, G. (2005) · Marine Biology · doi:10.1007/s00227-005-1596-7 · Cited by 168
Rose, A. L., Salmon, T. P., Lukondeh, T., Neilan, B. A., & Waite, T. D. (2005) · Environmental Science & Technology · doi:10.1021/es048766c · Cited by 148
Kustka, A. B., Shaked, Y., Milligan, A. J., King, D. W., & Morel, F. M. M. (2005) · Limnology and Oceanography · doi:10.4319/lo.2005.50.4.1172 · Cited by 141
Saragosti, E., Tchernov, D., Katsir, A., & Shaked, Y. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012508 · Cited by 128
Rapid photo-oxidation of Mn(II) mediated by humic substances
Nico, P., Anastasio, C., & Zasoski, R. J. (2002) · Geochimica et Cosmochimica Acta · doi:10.1016/s0016-7037(02)01001-3 · Cited by 116
The distribution of hydrogen peroxide in the southern and central Atlantic ocean
Yuan, J., & Shiller, A. M. (2001) · Deep Sea Research Part II Topical Studies in Oceanography · doi:10.1016/s0967-0645(01)00026-1 · Cited by 111
Rose, A. L., Webb, E. A., Waite, T. D., & Moffett, J. W. (2008) · Environmental Science & Technology · doi:10.1021/es7024609 · Cited by 110
Biotransformations of Manganese
Tebo, B. M., Clement, B., & Dick, G. J. (2007) · Wiley eBooks · doi:10.1128/9781555815882.ch100 · Cited by 105
Kim, D., Nakamura, A., Okamoto, T., Komatsu, N., Oda, T., Iida, T., Ishimatsu, A., & Muramatsu, T. (2000) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(00)00161-6 · Cited by 100
Role of extracellular peroxidase in the superoxide production by wheat root cells
Minibayeva, F. V., Gordon, L. K., Kolesnikov, O. P., & Chasov, A. V. (2001) · PROTOPLASMA · doi:10.1007/bf01289421 · Cited by 88
Rose, A. L., Moffett, J. W., & Waite, T. D. (2008) · Analytical Chemistry · doi:10.1021/ac7018975 · Cited by 87
Rose, A. L. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00124 · Cited by 84
Measurements of superoxide radical concentration and decay kinetics in the Gulf of Alaska
Hansard, S. P., Vermilyea, A. W., & Voelker, B. M. (2010) · Deep Sea Research Part I Oceanographic Research Papers · doi:10.1016/j.dsr.2010.05.007 · Cited by 80
Self-citationGodrant, A., Rose, A. L., Sarthou, G., & Waite, T. D. (2009) · Limnology and Oceanography Methods · doi:10.4319/lom.2009.7.682 · Cited by 63
Cannio, R. (2000) · Frontiers in bioscience · doi:10.2741/cannio · Cited by 60
Extracellular superoxide dismutase from Streptococcus pyogenes type 12 strain is manganese-dependent
Gerlach, D., Reichardt, W., & Vettermann, S. (1998) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1998.tb12914.x · Cited by 59
Heller, M. I., & Croot, P. L. (2010) · Journal of Geophysical Research Atmospheres · doi:10.1029/2009jc006021 · Cited by 58
Dynamics of nonphotochemical superoxide production in the Great Barrier Reef lagoon
Rose, A. L., Godrant, A., Godrant, A., Furnas, M. J., & Waite, T. D. (2010) · Limnology and Oceanography · doi:10.4319/lo.2010.55.4.1521 · Cited by 56
Formation of Metallogenium-like structures by a manganese-oxiding fungus
Emerson, D., Garen, R. E., & Ghiorse, W. C. (1989) · Archives of Microbiology · doi:10.1007/bf00413134 · Cited by 51
Hydrogen peroxide in deep waters of the North Pacific Ocean
Yuan, J., & Shiller, A. M. (2004) · Geophysical Research Letters · doi:10.1029/2003gl018439 · Cited by 37
Cited by
Superoxide dismutases and superoxide reductases
Sheng, Y., Abreu, I. A., Cabelli, D. E., Maroney, M. J., Miller, A.-F., Teixeira, M., & Valentine, J. S. (2014) · Chemical Reviews · doi:10.1021/cr4005296 · Cited by 1,081
The interplay of microbially mediated and abiotic reactions in the biogeochemical Fe cycle
Melton, E. D., Swanner, E. D., Behrens, S., Schmidt, C., & Kappler, A. (2014) · Nature Reviews Microbiology · doi:10.1038/nrmicro3347 · Cited by 899
An evolving view on biogeochemical cycling of iron
Kappler, A., Bryce, C., Mansor, M., Lueder, U., Byrne, J. M., & Swanner, E. D. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-020-00502-7 · Cited by 854
The microbial contribution to reactive oxygen species dynamics in marine ecosystems
Zinser, E. R. (2018) · Environmental Microbiology Reports · doi:10.1111/1758-2229.12626 · Cited by 78
Metadata
- Authors
- Diaz, J. M., Hansel, C. M., Voelker, B. M., Mendes, C. M., Andeer, P. F., & Zhang, T.
- Venue
- Science
- Published
- 2013-06-07
- Volume
- 340
- Issue
- 6137
- Pages
- 1223-1226
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2007698854
- Cited by
- 364
- References
- 42
- FWCI
- 14.07
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
