The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Long-Term Dynamics of Adaptation in Asexual Populations
Abstract
The Fit Get Fitter: Advances in modern biology have allowed us to measure evolutionary fitness and estimate the rate of fixation of beneficial mutations. Drawing on the Long-Term Evolution Experiment, studying the evolution of Escherichia coli in a constant environment, Wiser et al. (p. 1364 , published online 14 November) demonstrate that even after 50,000 generations over 20 years, gains in fitness show no evidence of leveling off. Instead, fitness is following a power-law relationship that is dependent on epistasis and clonal interference.
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Cites
Bayesian model selection in social research
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Self-citationDarwinian Evolution Can Follow Only Very Few Mutational Paths to Fitter Proteins
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Genome evolution and adaptation in a long-term experiment with Escherichia coli
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Self-citationEvolution of high mutation rates in experimental populations of E. coli
Sniegowski, P. D., Gerrish, P. J., & Lenski, R. E. (1997) · Nature · doi:10.1038/42701 · Cited by 879
Self-citationBlount, Z. D., Borland, C. Z., & Lenski, R. E. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803151105 · Cited by 840
Self-citationKawecki, T. J., Lenski, R. E., Ebert, D., Hollis, B., Olivieri, I., & Whitlock, M. C. (2012) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2012.06.001 · Cited by 807
Self-citationThe fate of competing beneficial mutations in an asexual population
Gerrish, P. J., & Lenski, R. E. (1998) · Genetica · doi:10.1023/a:1017067816551 · Cited by 772
Self-citationAdaptive evolution of highly mutable loci in pathogenic bacteria
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The dynamics of molecular evolution over 60,000 generations
Good, B. H., McDonald, M. J., Barrick, J. E., Lenski, R. E., & Desai, M. M. (2017) · Nature · doi:10.1038/nature24287 · Cited by 730
Self-citationA spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity
Waclaw, B., Bozic, I., Pittman, M. E., Hruban, R. H., Vogelstein, B., & Nowak, M. A. (2015) · Nature · doi:10.1038/nature14971 · Cited by 486
Quantifying the local adaptive landscape of a nascent bacterial community
Ascensao, J. A., Wetmore, K. M., Good, B. H., Arkin, A. P., & Hallatschek, O. (2023) · Nature Communications · doi:10.1038/s41467-022-35677-5 · Cited by 447
Adaptive Evolution within Gut Microbiomes of Healthy People
Zhao, S., Lieberman, T. D., Poyet, M., Kauffman, K. M., Gibbons, S. M., Groussin, M., Xavier, R. J., & Alm, E. J. (2019) · Cell Host & Microbe · doi:10.1016/j.chom.2019.03.007 · Cited by 434
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Metadata
- Authors
- Wiser, M. J., Ribeck, N., & Lenski, R. E.
- Venue
- Science
- Published
- 2013-12-13
- Volume
- 342
- Issue
- 6164
- Pages
- 1364-1367
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2016687536
- Cited by
- 591
- References
- 39
- FWCI
- 27.92
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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