The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.
Experimental evolution and the dynamics of adaptation and genome evolution in microbial populations
Open accessAbstract
Evolution is an on-going process, and it can be studied experimentally in organisms with rapid generations. My team has maintained 12 populations of Escherichia coli in a simple laboratory environment for >25 years and 60 000 generations. We have quantified the dynamics of adaptation by natural selection, seen some of the populations diverge into stably coexisting ecotypes, described changes in the bacteria’s mutation rate, observed the new ability to exploit a previously untapped carbon source, characterized the dynamics of genome evolution and used parallel evolution to identify the genetic targets of selection. I discuss what the future might hold for this particular experiment, briefly highlight some other microbial evolution experiments and suggest how the fields of experimental evolution and microbial ecology might intersect going forward.
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Cites
Deatherage, D. E., & Barrick, J. E. (2014) · Methods in Molecular Biology · doi:10.1007/978-1-4939-0554-6_12 · Cited by 1,609
Lenski, R. E., Rose, M. R., Simpson, S. C., & Tadler, S. C. (1991) · The American Naturalist · doi:10.1086/285289 · Cited by 1,580
Self-citationEvolution Experiments with Microorganisms: The Dynamics and Genetic Bases of Adaptation
Elena, S. F., & Lenski, R. E. (2003) · Nature Reviews Genetics · doi:10.1038/nrg1088 · Cited by 1,386
Self-citationAdaptive radiation in a heterogeneous environment
Rainey, P. B., & Travisano, M. (1998) · Nature · doi:10.1038/27900 · Cited by 1,306
Genome evolution and adaptation in a long-term experiment with Escherichia coli
Barrick, J. E., Yu, D. S., Yoon, S. H., Jeong, H., Oh, T. K., Schneider, D., Lenski, R. E., & Kim, J. F. (2009) · Nature · doi:10.1038/nature08480 · Cited by 1,184
Self-citationContingency and Determinism in Replicated Adaptive Radiations of Island Lizards
Losos, J. B., Jackman, T. R., Larson, A., Queiroz, K. D., & Rodrı́guez-Schettino, L. (1998) · Science · doi:10.1126/science.279.5359.2115 · Cited by 1,124
Lenski, R. E., & Travisano, M. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.15.6808 · Cited by 1,016
Self-citationEvolution of high mutation rates in experimental populations of E. coli
Sniegowski, P. D., Gerrish, P. J., & Lenski, R. E. (1997) · Nature · doi:10.1038/42701 · Cited by 879
Self-citationBlount, Z. D., Borland, C. Z., & Lenski, R. E. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803151105 · Cited by 840
Self-citationThe Molecular Diversity of Adaptive Convergence
Tenaillon, O., Rodríguez-Verdugo, A., Gaut, R. L., McDonald, P., Bennett, A. F., Long, A. D., & Gaut, B. S. (2012) · Science · doi:10.1126/science.1212986 · Cited by 815
Cited by
Contingency and determinism in evolution: Replaying life’s tape
Blount, Z. D., Lenski, R. E., & Losos, J. B. (2018) · Science · doi:10.1126/science.aam5979 · Cited by 590
Self-citationBiofilms: Understanding the structure and contribution towards bacterial resistance in antibiotics
Shree, P., Singh, C. K., Sodhi, K. K., Surya, J. N., & Singh, D. K. (2023) · Medicine in Microecology · doi:10.1016/j.medmic.2023.100084 · Cited by 396
Reintroducing mothur: 10 Years Later
Schloss, P. D. (2020) · Applied and Environmental Microbiology · doi:10.1128/aem.02343-19 · Cited by 285
Experimental evolution as a high-throughput screen for genetic adaptations
Cooper, V. S. (2018) · mSphere · doi:10.1128/msphere.00121-18 · Cited by 126
Mutalik, V. K., & Arkin, A. P. (2022) · iScience · doi:10.1016/j.isci.2022.104121 · Cited by 32
Metadata
- Authors
- Lenski, R. E.
- Venue
- The ISME Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2017-05-16
- Volume
- 11
- Issue
- 10
- Pages
- 2181-2194
- ISSN
- 1751-7362 (ISSN-L)
- 1751-7370
- OpenAlex
- W2616082873
- Cited by
- 377
- References
- 109
- FWCI
- 17.02
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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