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Cited by 537

The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.

Single-Cell Genomics Reveals Hundreds of Coexisting Subpopulations in Wild Prochlorococcus

Open access
Kashtan, Nadav, Roggensack, Sara E., Rodrigue, Sébastien, Thompson, Jessie W., Biller, Steven J., Coe, Allison, Ding, Huiming, Marttinen, Pekka, Malmstrom, Rex R., Stocker, Roman, Follows, Michael J., Stepanauskas, Ramunas, Chisholm, Sallie W.·2014·Science

Abstract

Cyanobacterial Diversity: What does it mean to be a global species? The marine cyanobacterium Prochlorococcus is ubiquitous and, arguably, the most abundant and productive of all living organisms. Although to our eyes the seas look uniform, to a bacterium the ocean's bulk is a plethora of microhabitats, and by large-scale single-cell genomic analysis of uncultured cells, Kashtan et al. (p. 416 ; see the Perspective by Bowler and Scanlan ) reveal that Prochlorococcus has diversified to match. This “species” constitutes a mass of subpopulations—each with million-year ancestry—that vary seasonally in abundance. The subpopulations in turn have clades nested within that show covariation between sets of core alleles and variable gene content, indicating flexibility of responses to rapid environmental changes. Large sets of coexisting populations could be a general feature of other free-living bacterial species living in highly mixed habitats.

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Metadata

Authors
Kashtan, N., Roggensack, S. E., Rodrigue, S., Thompson, J. W., Biller, S. J., Coe, A., Ding, H., Marttinen, P., Malmstrom, R. R., Stocker, R., Follows, M. J., Stepanauskas, R., & Chisholm, S. W.
Venue
Science
Published
2014-04-25
Volume
344
Issue
6182
Pages
416-420
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2037015298
Cited by
537
References
84
FWCI
50.90
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Single-Cell Genomics Reveals Hundreds of Coexisting Subpopulations in Wild Prochlorococcus. https://app.cochat.ai/papers/10.1126/science.1248575
The paper
Kashtan, N., Roggensack, S. E., Rodrigue, S., Thompson, J. W., Biller, S. J., Coe, A., Ding, H., Marttinen, P., Malmstrom, R. R., Stocker, R., Follows, M. J., Stepanauskas, R., & Chisholm, S. W. (2014). Single-Cell Genomics Reveals Hundreds of Coexisting Subpopulations in Wild Prochlorococcus. Science. https://doi.org/10.1126/science.1248575

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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