The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal
Open accessAbstract
Gata6 Controls Peritoneal Macs: Macrophages seed tissues throughout the body and are shaped both phenotypically and functionally by the microenvironment they inhabit. Despite such heterogeneity, most tissue macrophages self-renew by local proliferation. How this is regulated, however, is unclear.Rosas et al.(p.645, published online 24 April) used gene expression analysis to show that the transcription factor Gata6 is specifically expressed in peritoneal macrophages. Gata6 was critical for maintaining the transcriptional signature of peritoneal macrophages and for their proliferative renewal during homeostasis and under inflammatory conditions.
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DAVID: Database for Annotation, Visualization, and Integrated Discovery
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Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
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“An additional study (16) identified genes specific to peritoneal macrophages when compared to other tissues and there was a similar over-representation of genes from this list that were down regulated in the absence of Gata6 (Fig.”
GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.
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Cited by
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
Lavin, Y., Winter, D., Blecher-Gonen, R., David, E., Keren-Shaul, H., Merad, M., Jung, S., & Amit, I. (2014) · Cell · doi:10.1016/j.cell.2014.11.018 · Cited by 2,167
Origin and functions of tissue macrophages
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Gosselin, D., Link, V. M., Romanoski, C. E., Fonseca, G. J., Eichenfield, D. Z., Spann, N. J., Stender, J. D., Chun, H. B., Garner, H., Geissmann, F., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.023 · Cited by 1,307
Macrophages Facilitate Electrical Conduction in the Heart
Hulsmans, M., Clauss, S., Xiao, L., Aguirre, A. D., King, K. R., Hanley, A., Hucker, W. J., Wülfers, E. M., Seemann, G., Courties, G., et al. (2017) · Cell · doi:10.1016/j.cell.2017.03.050 · Cited by 1,011
Macrophages: Development and Tissue Specialization
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Metadata
- Authors
- Rosas, M., Davies, L. C., Giles, P. J., Liao, C.-T., Kharfan, B., Stone, T. C., O’Donnell, V. B., Fraser, D. J., Jones, S. A., & Taylor, P. R.
- Venue
- Science
- Published
- 2014-05-09
- Volume
- 344
- Issue
- 6184
- Pages
- 645-648
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2022485121
- Cited by
- 377
- References
- 6
- FWCI
- 15.43
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal. https://app.cochat.ai/papers/10.1126/science.1251414
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- Rosas, M., Davies, L. C., Giles, P. J., Liao, C.-T., Kharfan, B., Stone, T. C., O’Donnell, V. B., Fraser, D. J., Jones, S. A., & Taylor, P. R. (2014). The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal. Science. https://doi.org/10.1126/science.1251414
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
