High thermodynamic stability of parametrically designed helical bundles

Huang, Po-Ssu, Oberdorfer, Gustav, Xu, Chunfu, Pei, Xue Y., Nannenga, Brent L., Rogers, Joseph M., DiMaio, Frank, Gonen, Tamir, Luisi, Ben, Baker, David·2014·Science

DOI 10.1126/science.1257481

Cited by (277)

Items 101–200 of 277

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A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation
Dale F. Kreitler, Zhihui Yao, Jay D. Steinkruger, D.E. Mortenson, Lijun Huang, Ritesh Mittal, Benjamin R. Travis, Katrina T. Forest, Samuel H. Gellman · 2019 · Journal of the American Chemical Society
Role of backbone strain in de novo design of complex α/β protein structures
Nobuyasu Koga, Rie Koga, Gaohua Liu, Javier Castellanos, Gaetano Thomas Montelione, David A. Baker · 2021 · Nature Communications
De Novo Proteins with Life-Sustaining Functions Are Structurally Dynamic
Grant S. Murphy, Jack B. Greisman, Michael H. Hecht · 2015 · Journal of Molecular Biology
Improving the Thermostability and Catalytic Efficiency of the Subunit‐Fused Nitrile Hydratase by Semi‐Rational Engineering
Yuanyuan Xia, Wenjing Cui, Zhongyi Cheng, Łukasz Pepłowski, Zhongmei Liu, Michihiko Kobayashi, Zhemin Zhou · 2017 · ChemCatChem
Better together: building protein oligomers naturally and by design
Rebecca E. A. Gwyther, D. Dafydd Jones, Harley L. Worthy · 2019 · Biochemical Society Transactions
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Rui Guo, Nairiti J. Sinha, Rajkumar Misra, Yao Tang, Matthew G. Langenstein, Kyunghee Kim, Jeffrey A. Fagan, Christopher J. Kloxin, Grethe Vestergaard Jensen, Darrin J. Pochan et al. · 2022 · Biomacromolecules
Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene
Young Hyun No, Nam Hyeong Kim, Bramaramba Gnapareddy, Bumjoon Choi, Yong-Tae Kim, Sreekantha Reddy Dugasani, One‐Sun Lee, Kook-Han Kim, Young-Seon Ko, Sang Woo Lee et al. · 2017 · The Journal of Physical Chemistry Letters
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Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins
Sergio Romero‐Romero, Miguel Costas, Adela Rodríguez‐Romero, D. Alejandro Fernández‐Velasco · 2015 · Physical Chemistry Chemical Physics
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H. Y. Vincent Ching, Florencia C. Mascali, Hélène Charlotte Bertrand, Eduardo M. Bruch, Paul Demay‐Drouhard, Rodolfo Maximiliano Rasia, Clotilde Policar, Leandro C. Tabares, Sun Un · 2016 · The Journal of Physical Chemistry Letters
Coiled-coil inspired functional inclusion bodies
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From peptides to proteins: coiled-coil tetramers to single-chain 4-helix bundles
Elise A. Naudin, Katherine I. Albanese, Abigail J. Smith, Bram Mylemans, Emily G. Baker, Orion David Weiner, David M. Andrews, Natalie J. Tigue, Nigel J. Savery, Derek N. Woolfson · 2022 · Chemical Science
The role of directional interactions in the designability of generalized heteropolymers
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RamaNet: Computational de novo helical protein backbone design using a long short-term memory generative adversarial neural network
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Haiyan Liu, Quan Chen · 2016 · Current Opinion in Structural Biology
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Florencia C. Mascali, H. Y. Vincent Ching, Rodolfo Maximiliano Rasia, Sun Un, Leandro C. Tabares · 2016 · Angewandte Chemie
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Jack W. Heal, Gail J. Bartlett, Christopher W. Wood, Andrew R. Thomson, Derek N. Woolfson · 2018 · Bioinformatics
Controlling Association and Separation of Gold Nanoparticles with Computationally Designed Zinc-Coordinating Proteins
Matthew J. Eibling, Christopher M. MacDermaid, Zhaoxia Qian, Christopher J. Lanci, So‐Jung Park, Jeffery G. Saven · 2017 · Journal of the American Chemical Society
Rational design of photosynthetic reaction center protein maquettes
Nathan M. Ennist, Steven E. Stayrook, P. Leslie Dutton, Christopher C. Moser · 2022 · Frontiers in Molecular Biosciences
Phase separation-based visualization of protein–protein interactions and kinase activities in plants
Alaeddine Safi, Wouter Smagghe, Amanda Costa Gonçalves, Wang Qing, Ke Xu, Ana Ibis Fernandez, Benjamin Cappe, Franck B. Riquet, Evelien Mylle, Dominique Eeckhout et al. · 2023 · The Plant Cell
A de novo designed coiled coil-based switch regulates the microtubule motor kinesin-1
Jessica A. Cross, William Dawson, Shivam Shukla, Johannes F. Weijman, Judith Mantell, Mark P. Dodding, Derek N. Woolfson · 2024 · Nature Chemical Biology
Computational Treatment of Metalloproteins
Michael R. Nechay, Crystal E. Valdez, Anastassia N. Alexandrova · 2015 · The Journal of Physical Chemistry B
A generic framework for hierarchical de novo protein design
Harteveld, Zander, Bonet, Jaume, Rosset, Stéphane, Yang, Che, Sesterhenn, Fabian, Correia, Bruno E. · 2022 · Proceedings of the National Academy of Sciences
A De Novo Designed Esterase with p-Nitrophenyl Acetate Hydrolysis Activity
Guanlin Li, Li Xu, Houjin Zhang, Junjun Liu, Jinyong Yan, Yunjun Yan · 2020 · Molecules
Towards descriptor of elementary functions for protein design
Igor N. Berezovsky · 2019 · Current Opinion in Structural Biology
Principles and Methods in Computational Membrane Protein Design
Anastassia Andreevna Vorobieva · 2021 · Journal of Molecular Biology
Validation of de novo designed water‐soluble and transmembrane β‐barrels by in silico folding and melting
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James T. MacDonald, Paul S. Freemont · 2016 · Biochemical Society Transactions
De novo sequence redesign of a functional Ras‐binding domain globally inverted the surface charge distribution and led to extreme thermostability
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In Silico Engineering of Synthetic Binding Proteins from Random Amino Acid Sequences
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A Photoswitchable Trivalent Cluster Mannoside to Probe the Effects of Ligand Orientation in Bacterial Adhesion
Guillaume Despras, Leonhard Möckl, Anne Sofie Busk Heitmann, Insa Stamer, Christoph Bräuchle, Thisbe K. Lindhorst · 2019 · ChemBioChem
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Pallavi Prasad, Dhanashree Selvan, Saumen Chakraborty · 2020 · Chemistry - A European Journal
Rational Construction of Compact de Novo- Designed Biliverdin-Binding Proteins
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Artur Meller, Michael D. Ward, Jonathan H. Borowsky, Jeffrey M. Lotthammer, Meghana Kshirsagar, Felipe Oviedo, Juan Lavista Ferres, Gregory R. Bowman · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
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Hallucination of closed repeat proteins containing central pockets
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