The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Cyclic Stretching Stimulates Synthesis of Matrix Components by Arterial Smooth Muscle Cells in Vitro
Abstract
Rabbit aortic medial cells were grown on purified elastin membranes, which were then subjected to repeated elongation and relaxation or to agitation without stretching. Cells remained attached to the membranes, and cyclic stretching resulted in a two- to fourfold increase in rates of collagen, hyaluronate, and chondroitin 6-sulfate synthesis over those in agitated or stationary preparations. Synthesis of types I and III collagen was increased to the same degree. Stretching did not increase rates of chondroitin 4-sulfate or dermatan sulfate synthesis. Differences were not attributable to differences in cell number, for DNA synthetic rates were not increased by stretching. The model system devised to demonstrate these effects provides a means for relating various modes of mechanical stimulation to cell metabolism.
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Cites
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Enzymatic Methods for the Determination of Small Quantities of Isomeric Chondroitin Sulfates
Saito, H., Yamagata, T., & Suzuki, S. (1968) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)93575-1 · Cited by 1,370
Relation of Structure to Function of the Tissues of the Wall of Blood Vessels
Burton, A. C. (1954) · Physiological Reviews · doi:10.1152/physrev.1954.34.4.619 · Cited by 798
Structural Basis for the Static Mechanical Properties of the Aortic Media
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Self-citationChung, E., & Miller, E. J. (1974) · Science · doi:10.1126/science.183.4130.1200 · Cited by 524
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Response of the Rat Aortic Media to Hypertension: Morphological and Chemical Studies
WOLINSKY, H. (1970) · Circulation Research · doi:10.1161/01.res.26.4.507 · Cited by 336
Myosin synthesis in cultures of differentiating chicken embryo skeletal muscle
Paterson, B., & Strohman, R. C. (1972) · Developmental Biology · doi:10.1016/0012-1606(72)90050-4 · Cited by 324
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Mechanotransduction and extracellular matrix homeostasis
Humphrey, J. D., Dufresne, E. R., & Schwartz, M. A. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3896 · Cited by 2,124
Sutton-Tyrrell, K., Najjar, S. S., Boudreau, R. M., Venkitachalam, L., Kupelian, V., Simonsick, E. M., Havlik, R., Lakatta, E. G., Spurgeon, H., Kritchevsky, S., et al. (2005) · Circulation · doi:10.1161/circulationaha.104.483628 · Cited by 1,249
Fuster, V (1994) · Circulation · doi:10.1161/01.cir.90.4.2126 · Cited by 848
Association Between Local Pulse Pressure, Mean Blood Pressure, and Large-Artery Remodeling
Boutouyrie, P., Bussy, C., Lacolley, P., Girerd, X., Laloux, B., & Laurent, S. (1999) · Circulation · doi:10.1161/01.cir.100.13.1387 · Cited by 451
O’Callaghan, C. J., & Williams, B. (2000) · Hypertension · doi:10.1161/01.hyp.36.3.319 · Cited by 286
Metadata
- Authors
- Leung, D. Y. M., Glagov, S., & Mathews, M. B.
- Venue
- Science
- Published
- 1976-02-06
- Volume
- 191
- Issue
- 4226
- Pages
- 475-477
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1974203601
- Cited by
- 698
- References
- 13
- FWCI
- 5.92
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
