The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Block of Ca 2+ Wave and Ca 2+ Oscillation by Antibody to the Inositol 1,4,5-Trisphosphate Receptor in Fertilized Hamster Eggs
Abstract
The concentration of cytoplasmic free calcium (Ca 2+ ) increases in various stimulated cells in a wave (Ca 2+ wave) and in periodic transients (Ca 2+ oscillations). These phenomena are explained by inositol 1,4,5-trisphosphate (IP 3 )-induced Ca 2+ release (IICR) and Ca 2+ -induced Ca 2+ release (CICR) from separate intracellular stores, but decisive evidence is lacking. A monoclonal antibody to the IP 3 receptor inhibited both IICR and CICR upon injection of IP 3 and Ca 2+ into hamster eggs, respectively. The antibody completely blocked sperm-induced Ca 2+ waves and Ca 2+ oscillations. The results indicate that Ca 2+ release in fertilized hamster eggs is mediated solely by the IP 3 receptor, and Ca 2+ -sensitized IICR, but not CICR, generates Ca 2+ waves and Ca 2+ oscillations.
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Cites
Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor
Takeshima, H., Nishimura, S., Matsumoto, T., Ishida, H., Kangawa, K., Minamino, N., Matsuo, H., Ueda, M., Hanaoka, M., Hirose, T., et al. (1989) · Nature · doi:10.1038/339439a0 · Cited by 1,146
Cited by
Inositol trisphosphate and calcium signalling
Berridge, M. J. (1993) · Nature · doi:10.1038/361315a0 · Cited by 6,545
The endoplasmic reticulum: structure, function and response to cellular signaling
Schwarz, D. S., & Blower, M. D. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2052-6 · Cited by 1,613
The Inositol Phosphate-Calcium Signaling System in Nonexcitable Cells
PUTNEY, J. W., & BIRD, G. S. J. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-5-610 · Cited by 502
Effects of rapid buffers on Ca2+ diffusion and Ca2+ oscillations
Wagner, J., & Keizer, J. (1994) · Biophysical Journal · doi:10.1016/s0006-3495(94)80500-4 · Cited by 477
Engineering Novel Metalloproteins: Design of Metal-Binding Sites into Native Protein Scaffolds
Lu, Y., Berry, S. M., & Pfister, T. D. (2001) · Chemical Reviews · doi:10.1021/cr0000574 · Cited by 375
Metadata
- Authors
- Miyazaki, S.-I., Yuzaki, M., Nakada, K., Shirakawa, H., Nakanishi, S., Nakade, S., & Mikoshiba, K.
- Venue
- Science
- Published
- 1992-07-10
- Volume
- 257
- Issue
- 5067
- Pages
- 251-255
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1990602082
- Cited by
- 500
- References
- 1
- FWCI
- 17.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Miyazaki, S.-I., Yuzaki, M., Nakada, K., Shirakawa, H., Nakanishi, S., Nakade, S., & Mikoshiba, K. (1992). Block of Ca 2+ Wave and Ca 2+ Oscillation by Antibody to the Inositol 1,4,5-Trisphosphate Receptor in Fertilized Hamster Eggs. Science. https://doi.org/10.1126/science.1321497
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
