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The Annexins and Exocytosis
Abstract
The annexins are a group of homologous proteins that bind phospholipids in the presence of calcium. They may provide a major pathway for communication between cellular membranes and their cytoplasmic environment. Annexins have a characteristic "bivalent" activity in the sense that they can draw two membranes together when activated by calcium. This has led to the hypothesis that certain members of this protein family may initiate contact and fusion between a secretory vesicle membrane and the plasma membrane during the process of exocytosis.
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Citations
Cited by
Annexins: From Structure to Function
Gerke, V., & Moss, S. E. (2002) · Physiological Reviews · doi:10.1152/physrev.00030.2001 · Cited by 2,029
Transcytosis: Crossing Cellular Barriers
TUMA, P. L., & HUBBARD, A. L. (2003) · Physiological Reviews · doi:10.1152/physrev.00001.2003 · Cited by 681
SNARE Complex Formation Is Triggered by Ca 2+ and Drives Membrane Fusion
Chen, Y. A., Scales, S. J., Patel, S. M., Doung, Y.-C., & Scheller, R. H. (1999) · Cell · doi:10.1016/s0092-8674(00)80727-8 · Cited by 417
Pierson, E. S., Miller, D. D., Callaham, D. A., Shipley, A. M., Rivers, B. A., Cresti, M., & Hepler, P. K. (1994) · The Plant Cell · doi:10.1105/tpc.6.12.1815 · Cited by 365
Multiple roles for the actin cytoskeleton during regulated exocytosis
Porat-Shliom, N., Milberg, O., Masedunskas, A., & Weigert, R. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1156-5 · Cited by 181
Metadata
- Authors
- Creutz, C. E.
- Venue
- Science
- Published
- 1992-11-06
- Volume
- 258
- Issue
- 5084
- Pages
- 924-931
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1978542181
- Cited by
- 548
- References
- 0
- FWCI
- 20.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- Creutz, C. E. (1992). The Annexins and Exocytosis. Science. https://doi.org/10.1126/science.1439804
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
