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Cited by 403

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Participation in Normal Immune Responses of a Metastasis-Inducing Splice Variant of CD44

Arch, Robert, Wirth, Karin, Hofmann, Martin, Ponta, Helmut, Matzku, Siegfried, Herrlich, Peter, Zöller, Margot·1992·Science

Abstract

A variant of the glycoprotein CD44 (CD44v) that shares sequences with variants causally involved in metastasis formation is transiently expressed on B and T lymphocytes and macrophages after antigenic stimulation and in the postnatal period. Antibodies to the variant hinder in vivo activation of both B and T cells. The observation that a protein domain that is expressed on CD44 and required for the lymphatic spread of tumor cells can catalyze an essential step in the process of lymphocyte activation supports the idea that metastasizing tumor cells mimic lymphocyte behavior.

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Crossref · 10.1126/science.1496383

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Metadata

Authors
Arch, R., Wirth, K., Hofmann, M., Ponta, H., Matzku, S., Herrlich, P., & Zöller, M.
Venue
Science
Published
1992-07-31
Volume
257
Issue
5070
Pages
682-685
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1992072758
Cited by
403
References
18
FWCI
14.78
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Participation in Normal Immune Responses of a Metastasis-Inducing Splice Variant of CD44. https://app.cochat.ai/papers/10.1126/science.1496383
The paper
Arch, R., Wirth, K., Hofmann, M., Ponta, H., Matzku, S., Herrlich, P., & Zöller, M. (1992). Participation in Normal Immune Responses of a Metastasis-Inducing Splice Variant of CD44. Science. https://doi.org/10.1126/science.1496383

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.