The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Diphosphonates Inhibit Formation of Calcium Phosphate Crystals in vitro and Pathological Calcification in vivo
Abstract
Two diphosphonates containing the P-C-P bond, CH 3 C(OH)(PO 3 HNa) 2 and H 2 C(PO 3 HNa) 2 , inhibit the crystallization of calcium phosphate in vitro and prevent aortic calcification of rats given large amounts of vitamin D 3 . The diphosphonates therefore have effects similar to those described for compounds containing the P-O-P bond but are active when administered orally.
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Citations
Cites
Effect of Pyrophosphate on Hydroxyapatite and Its Implications in Calcium Homeostasis
FLEISCH, H., RUSSELL, R. G. G., & STRAUMANN, F. (1966) · Nature · doi:10.1038/212901a0 · Cited by 517
Self-citationMechanisms of calcification: role of collagen, polyphosphates, and phosphatase
Fleish, H., & Neuman, W. F. (1961) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1961.200.6.1296 · Cited by 444
The inhibition of calcium hydroxyapatite crystal growth by polyphosphonates and polyphosphates
Francis, M. D. (1969) · Calcified Tissue Research · doi:10.1007/bf02058658 · Cited by 399
Self-citationMechanism of Calcification: Inhibitory Role of Pyrophosphate
FLEISCH, H., & BISAZ, S. (1962) · Nature · doi:10.1038/195911a0 · Cited by 278
Self-citationInhibition by pyrophosphate and polyphosphate of aortic calcification induced by vitamin D3 in rats.
Schibler, D., Russell, R. G. G., & Fleisch, H. A. (1968) · PubMed · Cited by 121
Self-citationInhibition of Aortic Calcification by means of Pyrophosphate and Polyphosphates
Fleisch, H. A., Schibler, D., Maerki, J., & FROSSARD, I. (1965) · Nature · doi:10.1038/2071300b0 · Cited by 86
Self-citationAmorphous calcium phosphatase in skeletal tissues.
Eanes, E. D., Termine, J. D., & As, P. (1967) · PubMed · Cited by 76
Inhibition of skin calcification (Calciphylaxis) by polyphosphates
Schibler, D., & Fleisch, H. A. (1966) · Cellular and Molecular Life Sciences · doi:10.1007/bf01901138 · Cited by 44
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Cited by
Bisphosphonates: Mechanisms of Action
Fleisch, H. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.1.0325 · Cited by 1,019
Self-citationBisphosphonates: An Update on Mechanisms of Action and How These Relate to Clinical Efficacy
RUSSELL, R. G. G., XIA, Z., DUNFORD, J. E., OPPERMANN, U., KWAASI, A., HULLEY, P. A., KAVANAGH, K. L., TRIFFITT, J. T., LUNDY, M. W., PHIPPS, R. J., et al. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1402.089 · Cited by 391
Phosphorus-Containing Polymers: A Great Opportunity for the Biomedical Field
Monge, S., Canniccioni, B., Graillot, A., & Robin, J.-J. (2011) · Biomacromolecules · doi:10.1021/bm2004803 · Cited by 317
Price, P. A., Faus, S. A., & Williamson, M. K. (2001) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.21.5.817 · Cited by 301
BM 21.0955, a potent new bisphosphonate to inhibit bone resorption.
Mühlbauer, R. C., Bauss, F., Schenk, R., Janner, M., Bosies, E., Strein, K., & Fleisch, H. (1991) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650060915 · Cited by 239
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Metadata
- Authors
- Francis, M. D., Graham, R., Russell, G., & Fleisch, H.
- Venue
- Science
- Published
- 1969-09-19
- Volume
- 165
- Issue
- 3899
- Pages
- 1264-1266
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2018777439
- Cited by
- 608
- References
- 8
- FWCI
- 30.40
- Type
- journal article
- Language
- en
- Open access
- closed
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- Francis, M. D., Graham, R., Russell, G., & Fleisch, H. (1969). Diphosphonates Inhibit Formation of Calcium Phosphate Crystals in vitro and Pathological Calcification in vivo. Science. https://doi.org/10.1126/science.165.3899.1264
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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