The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Isolation of an Active Human Transposable Element
Abstract
Two de novo insertions of truncated L1 elements into the factor VIII gene on the X chromosome have been identified that produced hemophilia A. A full-length L1 element that is the likely progenitor of one of these insertions was isolated by its sequence identity to the factor VIII insertion. This L1 element contains two open-reading frames and is one of at least four alleles of a locus on chromosome 22 that has been occupied by an L1 element for at least 6 million years.
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Citations
Cites
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
Origin and evolution of retroelements based upon their reverse transcriptase sequences
Xiong, Y., & Eickbush, T. H. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07536.x · Cited by 1,374
Origins and evolutionary relationships of retroviruses
Doolittle, R. F., Johnson, M. S., & McClure, M. A. (1989) · The Quarterly Review of Biology · doi:10.1086/416128 · Cited by 577
Cited by
Initial sequencing and analysis of the human genome
International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216
Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition
Feng, Q., Moran, J. V., Kazazian, H. H., & Boeke, J. D. (1996) · Cell · doi:10.1016/s0092-8674(00)81997-2 · Cited by 1,139
Self-citationHot L1s account for the bulk of retrotransposition in the human population
Brouha, B., Schustak, J., Badge, R. M., Lutz-Prigge, S., Farley, A. H., Moran, J. V., & Kazazian, H. H. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0831042100 · Cited by 1,073
Self-citationHigh frequency retrotransposition in cultured mammalian cells
Moran, J. V., Holmes, S. E., Naas, T. P., DeBerardinis, R. J., Boeke, J. D., & Kazazian, H. H. (1996) · Cell · doi:10.1016/s0092-8674(00)81998-4 · Cited by 1,022
Self-citationReverse Transcriptase Encoded by a Human Transposable Element
Mathias, S. L., Scott, A. F., Kazazian, H. H., Boeke, J. D., & Gabriel, A. (1991) · Science · doi:10.1126/science.1722352 · Cited by 773
Self-citation
Metadata
- Authors
- Dombroski, B. A., Mathias, S. L., Nanthakumar, E., Scott, A. F., & Kazazian, H. H.
- Venue
- Science
- Published
- 1991-12-20
- Volume
- 254
- Issue
- 5039
- Pages
- 1805-1808
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2080056745
- Cited by
- 443
- References
- 3
- FWCI
- 35.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dombroski, B. A., Mathias, S. L., Nanthakumar, E., Scott, A. F., & Kazazian, H. H. (1991). Isolation of an Active Human Transposable Element. Science. https://doi.org/10.1126/science.1662412
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
