The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Alcohol, Amines, and Alkaloids: A Possible Biochemical Basis for Alcohol Addiction
Abstract
Tetrahydropapaveroline is a benzyltetrahydroisoquinoline alkaloid derivative of the biogenic amine, dopamine. Alcohol, by way of its primary metabolite, acetaldehyde, competitively inhibits nicotinamide-adenine dinucleotide-linked aldehyde dehydrogenase and augments the formation of tetrahydropapaveroline in vitro. The limited capacity of brain to oxidize aldehydes may be of pharmacological importance because it facilitates the production of tetrahydropapaveroline in the presence of drugs which inhibit this enzyme.
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Cites
An Experimental Study of the Etiology of “Rum Fits” and Delirium Tremens
Isbell, H., Fraser, H. F., Wikler, A., Belleville, R. E., & Eisenman, A. J. (1955) · Quarterly Journal of Studies on Alcohol · doi:10.15288/qjsa.1955.16.001 · Cited by 520
Tissue and subcellular distribution of mammalian aldehyde-oxidizing capacity
Deltrich, R. A. (1966) · Biochemical Pharmacology · doi:10.1016/0006-2952(66)90220-6 · Cited by 238
Biochemical factors in alcoholism
Maickel, R. P. (1967) · Pergamon Press eBooks · Cited by 233
The alteration of serotonin metabolism to 5-hydroxytryptophol by ethanol ingestion in man.
Davis, V. E., Brown, H., Huff, J. A., & Cashaw, J. L. (1967) · PubMed · Cited by 189
Self-citationEthanol-induced alterations of norepinephrine metabolism in man.
Davis, V. E., Brown, H., Huff, J. A., & Cashaw, J. L. (1967) · PubMed · Cited by 131
Self-citationAcetaldehyde—an inhibitor of the enzymatic oxidation of 5-hydroxyindoleacetaldehyde
Lahti, R. A., & Majchrowicz, E. (1969) · Biochemical Pharmacology · doi:10.1016/0006-2952(69)90231-7 · Cited by 92
Raskin, N. H., & Sokoloff, L. (1968) · Science · doi:10.1126/science.162.3849.131 · Cited by 81
Biosynthesis of the Morphine Alkaloids
KIRBY, G. W. (1967) · Science · doi:10.1126/science.155.3759.170 · Cited by 80
Pharmakologie des Tetrahydropapaverolins und seine Entstehung aus Dopamin
Holtz, P., Stock, K., & Westermann, E. (1964) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/bf00246886 · Cited by 75
Inhibitory Influence of Ethanol on Serotonin Metabolism
Rosenfeld, G. (1960) · Experimental Biology and Medicine · doi:10.3181/00379727-103-25440 · Cited by 63
Cited by
Cellular and molecular mechanisms of drug dependence
Koob, G. F., & Bloom, F. E. (1988) · Science · doi:10.1126/science.2903550 · Cited by 2,070
Goldstein, A. (1976) · Science · doi:10.1126/science.959823 · Cited by 517
Alteration of ethanol self-administration by naltrexone
Altshuler, H. L., Phillips, P. E., & Feinhandler, D. A. (1980) · Life Sciences · doi:10.1016/0024-3205(80)90257-x · Cited by 397
Risk for alcoholism and individual differences in the stress-response-dampening effect of alcohol
Sher, K. J., & Levenson, R. W. (1982) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.91.5.350 · Cited by 344
Frederickson, R. C. A. (1977) · Life Sciences · doi:10.1016/0024-3205(77)90421-0 · Cited by 269
Metadata
- Authors
- Davis, V. E., & Walsh, M. J.
- Venue
- Science
- Published
- 1970-02-13
- Volume
- 167
- Issue
- 3920
- Pages
- 1005-1007
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2064489872
- Cited by
- 560
- References
- 13
- FWCI
- 23.34
- Type
- journal article
- Language
- en
- Open access
- closed
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- Davis, V. E., & Walsh, M. J. (1970). Alcohol, Amines, and Alkaloids: A Possible Biochemical Basis for Alcohol Addiction. Science. https://doi.org/10.1126/science.167.3920.1005
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
