Alteration of ethanol self-administration by naltrexone
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The endogenous opioid system plays a strong role in the development of addiction to every class of drug.
“While opiate drugs are themselves strongly addictive, the role of the endogenous opioid system in addiction is not limited to these, as this system plays a strong role in the development of addiction to every class of drug (Altshuler et al 1980; Karras and Kane 1980; De Vry et al 1989; Kuzmin et al 1997; Ismayilova and Shoaib 2010; for a review see van Ree et al, 1999).”
From The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction (2012) · cites this paper as Altshuler et al 1980
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- Authors
- Altshuler, H. L., Phillips, P. E., & Feinhandler, D. A.
- Affiliations
- Texas Medical Center (US)
- ORCID
- Phillips, Paul E.
- Venue
- Life Sciences
- Publisher
- Elsevier BV
- Published
- 1980-03
- Volume
- 26
- Issue
- 9
- Pages
- 679-688
- ISSN
- 0024-3205 (ISSN-L)
- OpenAlex
- W1977436056
- Cited by
- 397
- References
- 20
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 5 · 2020: 5 · 2019: 4 · 2018: 4 · 2017: 4 · 2016: 8 · 2015: 9 · 2014: 4 · 2013: 7 · 2012: 12
- FWCI
- 3.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Life Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Keywords
- naltrexone, ethanol self-administration, ethanol reinforcement, opioid receptor blockade, rhesus monkeys, alcoholism, dose-response relationship
- MeSH terms
- Ethanol, Animals, Haplorhini, Dose-Response Relationship, Drug, Macaca mulatta, Male, Naloxone, Naltrexone, Reinforcement, Psychology, Self Administration
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