The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens
Abstract
K-region epoxides of the carcinogens benz [a] anthracene, dibenz [ a , h ]anthracene, and 7-methylbenz [a] anthracene are mutagenic in strains of Salmonella typhimurium designed to detect frameshift mutagens. Parent hydrocarbons, K-region diols and phenols and some other epoxides are inactive as mutagens in these tests. Polycyclic hydrocarbon epoxides, and other presumed proximal carcinogens, are discussed as examples of intercalating agents with reactive side chains. It has been shown previously that intercalating agents with reactive side chains are potent frameshift mutagens.
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Citations
Cites
Frameshift Mutations and the Genetic Code
Streisinger, G., Okada, Y., Emrich, J., Newton, J., Tsugita, A., Terzaghi, E., & Inouye, M. (1966) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1966.031.01.014 · Cited by 1,400
Cited by
An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens
Ames, B. N., Lee, F. D., & Durston, W. E. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.3.782 · Cited by 1,532
Self-citation(1979) · Advances in Cancer Research · doi:10.1016/s0065-230x(08)60848-9 · Cited by 1,163
Identifying Environmental Chemicals Causing Mutations and Cancer
Ames, B. N. (1979) · Science · doi:10.1126/science.373122 · Cited by 586
Self-citationThe Salmonella typhimurium/mammalian microsomal assay
Kier, L. E., Brusick, D. J., Auletta, A. E., Von Halle, E. S., Brown, M. M., Simmon, V. F., Dunkel, V., McCann, J., Mortelmans, K., Prival, M., et al. (1986) · Mutation Research/Reviews in Genetic Toxicology · doi:10.1016/0165-1110(86)90002-3 · Cited by 290
Boobis, A. R., & Nebert, D. W. (1977) · Advances in Enzyme Regulation · doi:10.1016/0065-2571(77)90024-3 · Cited by 12
Metadata
- Authors
- Ames, B. N., Sims, P., & Grover, P. L.
- Venue
- Science
- Published
- 1972-04-07
- Volume
- 176
- Issue
- 4030
- Pages
- 47-49
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2038069616
- Cited by
- 222
- References
- 1
- FWCI
- 22.04
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ames, B. N., Sims, P., & Grover, P. L. (1972). Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens. Science. https://doi.org/10.1126/science.176.4030.47
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
