The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Thyroid Hormone Action: A Cell-Culture System Responsive to Physiological Concentrations of Thyroid Hormones
Abstract
Cells from a rat pituitary tumor cell line will respond in vitro to physiological concentrations of L-thyroxine and L-triiodothyronine. The cells are grown in a culture medium that contains serum from a hypothyroid calf. Dose-response relationships of a variety of thyronine derivatives indicate that this system has a specificity of response which is similar to that observed in vitro.
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Citations
Cites
Burton, K. (1956) · Biochemical Journal · doi:10.1042/bj0620315 · Cited by 14,090
Conversion of Thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects
Braverman, L. E., Ingbar, S. H., & Sterling, K. (1970) · Journal of Clinical Investigation · doi:10.1172/jci106304 · Cited by 485
Cited by
Replacement of serum by hormones permits growth of cells in a defined medium
HAYASHI, I., & SATO, G. H. (1976) · Nature · doi:10.1038/259132a0 · Cited by 414
[6] The growth of cells in serum-free hormone-supplemented media
Bottenstein, J., Hayashi, I., Hutchings, S., Masui, H., Mather, J., McClure, D. B., Ohasa, S., Rizzino, A., Sato, G., Serrero, G., et al. (1979) · Methods in Enzymology · doi:10.1016/s0076-6879(79)58127-0 · Cited by 321
[46] Clonal strains of hormone-producing pituitary cells
Tashjian, A. H. (1979) · Methods in Enzymology · doi:10.1016/s0076-6879(79)58167-1 · Cited by 290
Bianco, A. C., Anderson, G., Forrest, D., Galton, V. A., Gereben, B., Kim, B. W., Kopp, P. A., Liao, X. H., Obregon, M. J., Peeters, R. P., et al. (2014) · Thyroid · doi:10.1089/thy.2013.0109 · Cited by 205
Romijn, H. J., van Huizen, F., & Wolters, P. S. (1984) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(84)90055-1 · Cited by 209
Metadata
- Authors
- Samuels, H. H., Tsai, J. S., & Cintron, R.
- Venue
- Science
- Published
- 1973-09-28
- Volume
- 181
- Issue
- 4106
- Pages
- 1253-1256
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1970895519
- Cited by
- 182
- References
- 2
- FWCI
- 10.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Thyroid Hormone Action: A Cell-Culture System Responsive to Physiological Concentrations of Thyroid Hormones. https://app.cochat.ai/papers/10.1126/science.181.4106.1253
- The paper
- Samuels, H. H., Tsai, J. S., & Cintron, R. (1973). Thyroid Hormone Action: A Cell-Culture System Responsive to Physiological Concentrations of Thyroid Hormones. Science. https://doi.org/10.1126/science.181.4106.1253
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
